文章摘要
Cunming Liu,Guolou Zhang,Mei Gao,Zhongyun Wang,Qianqing Wang,Chuanbao Han,Xiufeng Hao.[J].南京医科大学学报,2006,20(5):316~318
A clinical investigation of the relationship between different sedation depths and the restlessness after using midazolam as an adjuvant during regional anesthesia
  
DOI:10.7655
中文关键词: 
英文关键词: midazolam%sedation%regional anesthesia%restlessness
基金项目:
Cunming Liu  Guolou Zhang  Mei Gao  Zhongyun Wang  Qianqing Wang  Chuanbao Han  Xiufeng Hao
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中文摘要:
      
英文摘要:
      Objective: To investigate the relationship between different sedation depth and the restlessness after using midazolam as an adjuvant during regional anesthesia. Methods: One hundred and fifty patients undergoing regional anesthesia were randomly divided into three groups. In group A, the patients were sedated at the level of OAA/S Ⅳ with midazolam during regional anesthesia. In group B and C, the sedation depths were kept at the levels of Ⅲ and Ⅱ respectively. The changes of BP, HR and SpO2 were recorded before and after midazolam.The rate of restlessness was also evaluated. Results: Blood pressures decreased in certain degree at 5 and 10 min after midazolam compared with those before in all three groups. BP decreased over 20﹪ of the baseline in 4 cases in group A, in 5 cases in group B, and in 5 cases in group C. There was no significant difference in BP dropping among three groups. Compared with group B and C SpO2 dropped significantly at 3 and 5 min after midazolam in group C, in which SpO2 was less than 93﹪ in 8 cases. The restlessness rate in group C was 22﹪, which was significantly higher than those in group A (2﹪ ,P<0.01) and group B(4﹪ ,P<0.05). Conclusion: The sedation depth is related to the rate of restlessness when midazolam is used as an adjuvant during regional anesthesia. It is suggested that the appropriate sedation depth for the patients under regional anesthesia is OAA/S Ⅲ.
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