文章摘要
Chuncai Xue,Yigang Li.[J].南京医科大学学报,2007,(2):86~88
Value of D-Dimers in patients with acute aortic dissection
投稿时间:2006-11-06  
DOI:10.7655
中文关键词: 
英文关键词: D-dimer  aorta  dissection  coagulation
基金项目:
作者单位
Chuncai Xue Department of Cardiology, the People's Hospital of Binzhou, Binzhou 256610, China 
Yigang Li Department of Cardiology, Xinhua hospital, Shanghai JiaoTong university, Shanghai 200092, China 
摘要点击次数: 1115
全文下载次数: 945
中文摘要:
      
英文摘要:
       Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimers were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ ml, P < 0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.
查看全文   查看/发表评论  下载PDF阅读器
关闭