文章摘要
Xiaobing Ji,Zhijian Yang, Chunjian Li, Enzhi Jia, Zhuowen Xu,Sheng Zhang, Kejiang Cao,Wenzhu Ma.[J].南京医科大学学报,2008,28(4):246~249
The changes of Hs-CRP and WBC count after percutaneous coronary intervention in different types of coronary heart diseases
投稿时间:2008-04-10  
DOI:10.7655
中文关键词: 
英文关键词: high sensitive C-reactive protein(Hs-CRP)  coronary heart disease  percutaneous transluminal intervention(PCI)  WBC count
基金项目:
作者单位
Xiaobing Ji Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210020, Jiangsu Province, China 
Zhijian Yang  
Chunjian Li  
Enzhi Jia  
Zhuowen Xu  
Sheng Zhang  
Kejiang Cao  
Wenzhu Ma  
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中文摘要:
      
英文摘要:
      Objective: To investigate the regulation of High sensitive C-reactive protein(Hs-CRP) and WBC count in patients with coronary heart disease(CHD) by percutaneous transluminal intervention(PCI) and to discuss the mechanism of inflammatory reaction after coronary stenting. Methods:127 patients who received successful percutaneous transluminal coronary stenting, were divided into groups of stable angina(SAP), unstable angina(UAP), and acute myocardial infarction(AMI) according to their clinical types. Another 41 stable angina patients with more than 7o% of coronary artery tenosis who did not receive PCI served as control. Serum Hs-CRP levels and WBC count were determined before intervention, 3 days and 7 days post PCI and the data were analyzed statistically by t-test. Results: There showed no difference in clinical baseline characteristics between groups. The serum Hs-CRP level and WBC count was gradually raised in the UAP and AMI group(how about SAP group, and had no difference in CAG group and SAP group). After PCI serum Hs-CRP levels and WBC counts were significantly higher in the SAP group than in the coronary angiography group(CAG) at 3 days and had no difference at 7 days. In the UAP and AMI group, the serum Hs-CRP level at 3 days and 7 days declined obviously, however serum WBC count did not decrease apparently. Conclusion: The serum Hs-CRP level and WBC count elevate transiently after PCI. There are different inflammatory reactions in different types of coronary heart diseases after coronary stenting procedure.
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