文章摘要
Yefei Zhu, Zhongmin Tan,Lingyang Zhu,Hongxing Pan,Xuejun Zhang, Lei Xu,Huimin Qian,Ling Gu,Xun Ye,Chen Dong, Changjun Bao,Rongqiang Zhu,Fengcai Zhu, Hua Wang.[J].南京医科大学学报,2008,28(5):313~316
A Streptococcus suis serotype 2 caused streptococcal toxic shock syndrome(STSS) in a patient
投稿时间:2008-07-14  
DOI:10.7655
中文关键词: 
英文关键词: Streptococcus suis  streptococcal toxic shock syndrome  PCR
基金项目:
作者单位
Yefei Zhu Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Zhongmin Tan Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Lingyang Zhu Lianyungang Center for Disease Control and Prevention, Lianyungang 222003, Jiangsu Province, China 
Hongxing Pan Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Xuejun Zhang Lianyungang Center for Disease Control and Prevention, Lianyungang 222003, Jiangsu Province, China 
Lei Xu Lianyungang Center for Disease Control and Prevention, Lianyungang 222003, Jiangsu Province, China 
Huimin Qian Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Ling Gu Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Xun Ye Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Chen Dong Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Changjun Bao Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Rongqiang Zhu Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Fengcai Zhu Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
Hua Wang Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, Jiangsu Province,China 
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中文摘要:
      
英文摘要:
      Streptococcus suis (S. suis) is a Gram-positive, facultatively anaerobic coccus that has been implicated as the cause of a wide range of clinical disease syndromes in swine and other domestic animals. S. suis has also been implicated in disease in humans, especially among abattoir workers, swine and pork handlers. Here we report a case of streptococcal toxic shock syndrome(STSS) caused by S. suis in a 59-year-old man. Despite of intensive treatment, the patient died of shock with multiple organ failure 14 h after admission. One bacterial isolate obtained from blood culture was identified to the species level by biochemical tests and serological tests as S. suis serotype 2. Identification was confirmed by PCR amplification of genes encoding 16sRNA of S. suis and the capsule of S. suis serotype 2(cps 2J). Genes encoding virulence factors were also detected. An investigation to identify the source of S. suis revealed that several days before admission the affected man had been handling sick pigs or their meat. Transmission may occur through breaks in the skin of feet with tinea due to that no measures for personal protection was taken. This case should highten awareness of the potential for occupational exposure and human infection with S. suis.
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