文章摘要
Dandan Liu,Zheng Hu,Zhigang Liu,Bo Yang,Wenjuan Tu,Liang Li.[J].南京医科大学学报,2009,29(3):168~172
Chemical composition and antimicrobial activity of essential oil isolated from the cultured mycelia of Ganoderma japonicum
投稿时间:2009-01-25  
DOI:10.7655
中文关键词: 
英文关键词: Ganoderma japonicum  essential oil  antimicrobial activity  clinical pathogens
基金项目:
作者单位
Dandan Liu The Key Laboratory of Industrial Microbiology of Hubei Province, Hubei University of Technology, Wuhan 430068, China 
Zheng Hu The Key Laboratory of Industrial Microbiology of Hubei Province, Hubei University of Technology, Wuhan 430068, China 
Zhigang Liu The Key Laboratory of Industrial Microbiology of Hubei Province, Hubei University of Technology, Wuhan 430068, China 
Bo Yang The Key Laboratory of Industrial Microbiology of Hubei Province, Hubei University of Technology, Wuhan 430068, China 
Wenjuan Tu School of Biochemistry and Molecular Biology of Australian National University, Canberra, Australia 0200 
Liang Li The Key Laboratory of Industrial Microbiology of Hubei Province, Hubei University of Technology, Wuhan 430068, China 
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中文摘要:
      
英文摘要:
      Objective:To explore a new natural antibiotic. Methods:The chemical composition of the essential oil from Ganoderma japonicum (G. japonicum) mycelia was analyzed by gas chromatography-mass spectrometry(GC-MS). The antimicrobial activity of the oil was evaluated against eighteen microorganisms, including bacteria, mildew and yeast by using a disc diffusion method. Furthermore, the minimum inhibitory concentrations(MIC) and the minimum bactericidal concentrations(MBC) of the essential oil against twelve clinical pathogens were determined. Results:The main components of the oil were nerolidol, decadienal, linalool and benzyl alcohol. The antimicrobial results indicated that the oil inhibited all the tested bacterium, especially Methicillin-resistant Staphylococcus aureus (MRSA) in which the antibacterial activity exhibited a MBC of 1.03 mg/ml. Conclusion: The essential oil of G. japonicum mycelium has significant inhibitory activity. It is a potential medicinal resource that can be used as a natural antibiotic.
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