To understand the status of cognition，attitude and its influencing factorstoward hospice care of undergraduate students in a medical university， and provide reference for improving hospice careeducation of medical students in China. In this study， 520 undergraduate students from the medical university were selected for questionnaire survey. The results of the analysis indicated that cognition and attitude of the medical university were positively correlated（r=0.430，P<0.001）. The past hospice care education situation，perceived social support，meaning in life were the influencing factors of hospice care attitude. The interaction between social support and meaning in life wasmay affected attitude towards hospice care attitude and indirectly affects hospice care cognition（all P<0.05）. It is suggested that the comprehensive hospice education， comprehension of social support and sense of life will be taken as the focus of medical undergraduate hospice education to improve the cognition and attitude of medical undergraduates on hospice care.