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               ·482 ·                            南 京    医 科 大 学 学         报                        2025年4月


                A                                     B                          D
                       Sagittal view    Axial view        12 000 HU=2 031+10.61×ρ    500  *** ***  ***  ***  ***
                                                                 2
                                1 mm            1 mm            R =0.998 1          (μm)  400
                                                           9 000 P < 0.001
                   0 d                                                               300
                                                         HU  6 000                  Tooth movement  200
                   3 d                                     3 000                     100 0

                                                             0
                                                               0  200 400 600 800         0 3  7  14  21  28
                                                                          3
                   7 d                                           Density(mg/cm )                Time(d)
                A                                     C                          E
                                                             Posterior palatine foramen
                   d                                                  Palatal plane
                   14                                    M2        z                    M1     M2      1 mm
                                                                                                       z
                                                        M1
                   d                                               O                      C1     C2
                   21                                                    y
                                                                  x                           D
                                                                                              x
                                                                                                    O
                   d
                   28
                                                                                                        y
                 A:Sagittal and axial views of 3D reconstruction of orthodontic tooth movement at various time points(scale bar=1 mm). B:Linear fit curve of densi⁃
              ty⁃CT value relationship. C:Schematic diagram of centroid distance measurement:M1 represents the first molar,M2 represents the second molar,C1 is
              the centroid of the first molar,C2 is the centroid of the second molar,and vector D  is the directed line segment from C2 to C1. D:Trend of tooth move⁃
                            ***
              ment distance change, P < 0.001(n=5).
                                                  图3 牙齿移动距离的变化趋势
                                            Figure 3 Trends in orthodontic tooth movement
                         A               Sagittal view                      Axial view
                                          M1
                                                                                          M1
                                 M2


                                                                             p
                                               p
                                          t                             t
                                                          1 mm                              1 mm

                         B

                                                       Pore                Section at the
                               ROI 3D
                             reconstruction
                                                      coloring               midpoint
                                   0 d         3 d        7 d        14 d        21 d       28 d



                          ROI⁃p





                           ROI⁃t



                 A:Sagittal and axial CT sections. ROI⁃p represents the pressure zone,ROI⁃t represents the tension zone,M1 is the first molar,and M2 is the sec⁃
              ond molar(scale bar=1 mm). B:3D reconstruction of ROIs in tension and pressure zones. Blue regions indicate pore areas,while gray regions indicate
              bone tissue areas.
                                                    图4 ROI三维重建截面图
                                         Figure 4  3D reconstructed cross⁃sectional image of ROI
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