Page 141 - 南京医科大学学报自然科学版

第41卷第2期 鲁婕雨，石文翔，孔祥清. 高血压代谢组学研究进展［J］.
2021年2月 南京医科大学学报（自然科学版），2021，41（02）：286-291 ·291 ·

gy，2019，92（16）：e1890-e1898 fects of four different antihypertensive drugs on plasma
［45］ YU B，LI A H，METCALF G A，et al. Loss⁃of⁃function metabolomic profiles in patients with essential hyperten⁃
variants influence the human serum metabolome［J］. Sci sion［J］. PLoS One，2017：12，e187729
Adv，2016，2（8）：e1600800 ［55］ ALTMAIER E，FOBO G，HEIER M，et al. Metabolomics
［46］ KHAN A，SHIN M，JEE S H，et al. Global metabolomics approach reveals effects of antihypertensives and lipid ⁃
analysis of serum from humans at risk of thrombotic stroke lowering drugs［J］. Eur J Epidemiol，2014，29（5）：325-336
［J］. Analyst，2020，145（5）：1695-1705 ［56］ ALTMAIER E，MENNI C，HEIER M，et al. The pharma⁃
［47］ ZHU N，JIANG W，WANG Y，et al. Plasma levels of free cogenetic footprint of ace inhibition：a population⁃based
fatty acid differ in patients with left ventricular preserved， metabolomics［J］. PloS One，2016，11（4）：e153163
mid⁃range，and reduced ejection fraction［J］. BMC Cardio⁃ ［57］ SONN B J，SABEN J L，MCWILLIAMS G，et al. Predict⁃
vasc Disord，2018，18：104 ing response to lisinopril in treating hypertension：a pilot
［48］ SANTIAGO⁃HERNANDEZ A，MARTINEZ P J，MARTIN⁃ study［J］. Metabolomics，2019，15（10）：133
LORENZO M，et al. Differential metabolic profile associ⁃ ［58］ FLATEN H K，MONTE A A. The pharmacogenomic and
ated with the condition of normoalbuminuria in the hyper⁃ metabolomic predictors of ACE inhibitor and angiotensin
tensive population［J］. Nefrologia，2020，40（4）：440- Ⅱ［J］. Cardiovasc Drugs Ther，2017，31（4）：471-482
445 ［59］ CHENG S，SHAH S H，CORWIN E J，et al. Potential im⁃
［49］ POLONIS K，WAWRZYNIAK R，DAGHIR⁃WOJTKOWI⁃ pact and study considerations of metabolomics in cardio⁃
AK E，et al. Metabolomic signature of early vascular aging vascular health and disease：a scientific statement from
（EVA）in hypertension［J］. Front mol biosci，2020，7：12 the American Heart Association［J］. Circ Cardiovas Gen⁃
［50］REBHOLZ C M，LICHTENSTEIN A H，ZHENG Z，et al. et，2017，10（2）：. e000032
Serum untargeted metabolomic profile of the dietary ap⁃ ［60］ CHEN D，ZHAO X，SUI Z，et al. A multi⁃omics investiga⁃
proaches to stop hypertension［J］. Am J Clin Nutr，2018， tion of the molecular characteristics and classification of
108（2）：243-255 six metabolic syndrome relevant diseases［J］. Theranos⁃
［51］ JABLONSKI K L，KLAWITTER J，CHONCHOL M，et al. tics，2020，10（5）：2029-2046
Effect of dietary sodium restriction on human urinary me⁃ ［61］ STAMLER J，BROWN I J，YAP I K S，et al. Dietary and
tabolomic profiles［J］. Clin j Am Soc Nephrol，2015，10 urinary metabonomic factors possibly accounting for high⁃
（7）：1227-1234 er blood pressure of black compared with white Ameri⁃
［52］ DERKACH A，SAMPSON J，JOSEPH J，et al. Effects of cans：results of International Collaborative Study on macro
dietary sodium on metabolites：the dietary approaches to ⁃/micronutrients and blood pressure［J］. Hypertension，
stop［J］. Am J Clin Nutr，2017，106（4）：1131-1141 2013，62（6）：1074-1080
［53］ LIU X，WANG Y，GAO R，et al. Serum metabolomic re⁃ ［62］ GOÏTA Y，CHAO DE LA BARCA J M，KEÏTA A，et al.
sponse to exercise training in spontaneously hypertensive Sexual dimorphism of metabolomic profile in arterial hy⁃
rats［J］. J Am Soc Hyperten，2017，11（7）：428-436 pertension［J］. Sci Rep，2020，10（1）：7517
［54］ HILTUNEN T P，RIMPELÄ J M，MOHNEY R P，et al. Ef⁃ ［收稿日期］ 2020-10-29