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南京医科大学学报(自然科学版) 第42卷第10期
·1394 · Journal of Nanjing Medical University(Natural Sciences) 2022年10月
·基础医学·
模拟过氧化微环境中的钛表面特性及其腐蚀行为研究
高红媛 ,周以恒 ,邱 憬 1*
1
1,2
南京医科大学附属口腔医院种植科,江苏省口腔疾病研究重点实验室,江苏省口腔转化医学工程研究中心,江苏 南京 210029;
1
泰州市口腔医院修复科,江苏 泰州 225300
2
[摘 要] 目的:研究模拟过氧化微环境对钛表面特性及其腐蚀行为的影响。方法:将纯钛试件浸泡于不同模拟体液中,分为
Hanks’平衡盐溶液(HBSS)组、HBSS+牛血清白蛋白(BSA)组、HBSS+过氧化氢(H2O2 )组、HBSS+BSA+H2O2组。收集浸泡7 d后
的试件及浸提液,采用扫描电镜(scanning electron microscopy,SEM)、X 射线光电子能谱仪(X⁃ray photoelectron spectroscopy,
XPS)分析钛表面特性;采用电化学工作站检测不同模拟体液中纯钛试件的腐蚀行为;采用电感耦合等离子体发射光谱仪
(inductively coupled plasma optical emission spectrometer,ICP⁃OES)检测各组浸提液中的钛离子释放量。结果:SEM和XPS分析
结果显示,HBSS+H2O2组钛表面微形貌变化明显,钛和氧元素含量显著升高,其余各组无明显差异。电化学测试获得的奈奎斯
特图(Nyquist)、波特阻抗图、波特相位图以及等效电路拟合数据显示,HBSS+H2O2组钛表面氧化膜的腐蚀阻抗最小,HBSS+
BSA+H2O2组次之,HBSS+BSA 组和 HBSS 组最高。ICP⁃OES 检测发现,HBSS+H2O2组的钛离子释放量较其余各组显著增加。
结论:模拟过氧化微环境中H2O2会破坏钛表面氧化膜,加剧钛腐蚀行为,引发钛离子释放,而BSA和H2O2共同作用时,BSA可
抑制H2O2对钛表面的腐蚀。
[关键词] 钛;腐蚀;过氧化氢;牛血清白蛋白
[中图分类号] R783.1 [文献标志码] A [文章编号] 1007⁃4368(2022)10⁃1394⁃08
doi:10.7655/NYDXBNS20221007
Study of surface property and corrosion behavior of pure titanium in a simulated peroxidation
microenvironment
1,2 1 1*
GAO Hongyuan ,ZHOU Yiheng ,QIU Jing
Department of Oral Implantology,Affiliated Stomatological Hospital of Nanjing Medical University,Jiangsu
1
Province Key Laboratory of Oral Diseases,Jiangsu Privince Engineering Research Center of Stomatological
2
Trarslational Medicine,Nanjing 210029;Department of Prosthodontics,Taizhou Stomatological Hospital,Taizhou
225300,China
[Abstract] Objective:To study the effects of surface property and corrosion behavior of pure titanium in a simulated peroxidation
microenvironment. Methods:The pure titanium specimens were immersed in different simulated body fluids and divided into Hanks’
balanced salt solution(HBSS)group,HBSS+ bovine serum albumin(BSA)group,HBSS+hydrogen peroxide(H2O2 )group and HBSS+
BSA+H2O2 group. The test samples and soaking solutions after 7 days of immersion were collected,and the titanium surface properties
were analyzed by scanning electron microscopy(SEM)and X⁃ray photoelectron spectroscopy(XPS). An electrochemical potentiostat
was used to investigate the corrosion behaviors of pure titanium specimens in different simulated body fluids. The quantities of titanium
ion release in soaking solutions of different groups were detected by inductively coupled plasma optical emission spectrometer(ICP⁃
OES). Results:SEM and XPS analysis results demonstrated that the micro ⁃ morphology of titanium surface in HBSS + H 2O2 group
changed obviously with significant increases in the contents of titanium and oxygen,whereas there were no remarkable differences in
other groups. The Nyquist plots,Bode |Z| diagrams,Bode⁃phase diagrams and equivalent circuit fitting data obtained by electrochemical
[基金项目] 国家自然科学基金(81870799);江苏省重点研发计划(社会发展)项目(BE2019728);江苏高校优势学科建设工
程资助项目(2018-87)
∗
通信作者(Corresponding author),E⁃mail:qiujing@njmu.edu.cn