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［33］ WON E J，PARK H，YOON T J，et al. Genetherapy using ［44］ HE W J，YU Y，HUANG W，et al. The pseudogene
nanocarriers for pancreatic ductal adenocarcinoma：appli⁃ DUXAP8 promotes colorectal cancer cell proliferation，in⁃
cations and challenges in cancer therapeutics［J］. Pharma⁃ vasion，and migration by inducing epithelial ⁃ mesenchy⁃
ceutics，2022，14（1）：137 mal transition through interacting with EZH2 and
［34］ YANAGISAWA R，KOIZUMI T，KOYA T，et al. WT1 ⁃ H3K27me3［J］. Onco Targets Ther，2020，13：11059-
pulsed dendritic cell vaccine combined with chemothera⁃ 11070
py for resected pancreatic cancer in a phase Ⅰ study［J］. ［45］ FANG S，GAO H Y，TONG Y，et al. Long noncoding RNA
Anticancer Res，2018，38（4）：2217-2225 ⁃HOTAIR affects chemoresistance by regulating HOXA1
［35］ CHEN S，CHEN J Z，ZHAN Q，et al. H2AK119Ub1 and methylation in small cell lung cancer cells［J］. Lab In⁃
H3K27Me3 in molecular staging for survival prediction of vest，2016，96（1）：60-68
patients with pancreatic ductal adenocarcinoma［J］. Onco⁃ ［46］ FANG S，SHEN Y F，CHEN B，et al. H3K27me3 induces
target，2014，5（21）：10421-10433 multidrug resistance in small cell lung cancer by affecting
［36］ ZHOU X，GAO W，HUA H H，et al. LncRNA⁃BLACAT1 HOXA1 DNA methylation via regulation of the lncRNA
facilitates proliferation，migration and aerobic glycolysis HOTAIR［J］. Ann Transl Med，2018，6（22）：440
of pancreatic cancer cells by repressing CDKN1C via ［47］ LI J，LIAN Y F，YAN C S，et al. Long non⁃coding RNA
EZH2 ⁃ induced H3K27me3［J］. Front Oncol，2020，10： FOXP4⁃AS1 is an unfavourable prognostic factor and regu⁃
539805 lates proliferation and apoptosis in colorectal cancer［J］.
［37］ LÓPEZ J，AÑAZCO⁃GUENKOVA A M，MONTEAGUDO⁃ Cell Prolif，2017，50（1）：e12312
GARCÍA Ó，et al. Epigenetic and epitranscriptomiccon⁃ ［48］ CHEN R Y，JU Q，FENG L M，et al. The carcinogenic com⁃
trol in prostate cancer［J］. Genes，2022，13（2）：378 plex lncRNA FOXP4⁃AS1/EZH2/LSD1 accelerates proli⁃
［38］ NGOLLO M，LEBERT A，DAGDEMIR A，et al. The asso⁃ feration，migration and invasion of gastric cancer［J］. Eur
ciation between histone 3 lysine 27 trimethylation Rev Med Pharmacol Sci，2019，23（19）：8371-8376
（H3K27me3）and prostate cancer：relationship with clini⁃ ［49］ WU X C，XIAO Y，ZHOU Y，et al. LncRNA FOXP4⁃AS1
copathological parameters［J］. BMC Cancer，2014，14： is activated by PAX5 and promotes the growth of prostate
994 cancer by sequestering miR ⁃ 3184 ⁃ 5p to upregulate
［39］ CAO Z，SHI X L，TIAN F，et al. KDM6B is an androgen FOXP4［J］. Cell Death Dis，2019，10（7）：472
regulated gene and plays oncogenic roles by demethylat⁃ ［50］ WANG D，BAI T，CHEN G Y，et al. Upregulation of long
ing H3K27me3 at cyclin D1 promoter in prostate cancer non⁃coding RNA FOXP4⁃AS1 and its regulatory network
［J］. Cell Death Dis，2021，12（1）：2 in hepatocellular carcinoma［J］. Onco Targets Ther，
［40］ WANG Q，CHEN X，JIANG Y H，et al. Elevating 2019，12：7025-7038
H3K27me3 level sensitizes colorectal cancer to oxaliplatin ［51］ YE J F，FU Y，WANG Z F，et al. Long non⁃coding RNA
［J］. J Mol Cell Biol，2020，12（2）：125-137 FOXP4⁃AS1 facilitates the biological functions of hepato⁃
［41］ LEE Y M，KIM S H，KIM M S，et al. Epigeneticrole of his⁃ cellular carcinoma cells via downregulating ZC3H12D by
tone lysine methyltransferase and demethylase on the ex⁃ mediating H3K27me3 through recruitment of EZH2［J/
pression of transcription factors associated with the epi⁃ OL］. Cell Biol Toxicol，2021，2021. doi：10.1007/s10565-
thelial⁃to⁃mesenchymal transition of lung adenocarcinoma 021-09642-9
metastasis to the brain［J］. Cancers，2020，12（12）：3632 ［52］ HE L J，CAI M Y，XU G L，et al. Prognostic significance of
［42］ URBANOVA M，BUOCIKOVA V，TRNKOVA L，et al. overexpression of EZH2 and H3k27me3 proteins in gas⁃
DNA methylation mediates EMT gene expression in hu⁃ tric cancer［J］. Asian Pac J Cancer Prev，2012，13（7）：
man pancreatic ductal adenocarcinoma cell lines［J］. Int J 3173-3178
Mol Sci，2022，23（4）：2117 ［53］ 崔 黎，崔 莹，张红燕，等. 脑膜瘤组织中H3K27me3
［43］ JARROUX J，FORETEK D，BERTRAND C，et al. HO⁃ 的表达及临床意义［J］. 新乡医学院学报，2021，38（6）：
TAIR lncRNA promotes epithelial ⁃ mesenchymal transi⁃ 555-558
tion by redistributing LSD1 at regulatory chromatin re⁃ ［收稿日期］ 2022-02-20
gions［J］. EMBO Rep，2021，22（7）：e50193 （本文编辑：陈汐敏）