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                   by facilitates uptake of amyloid ⁃ beta by microglia[J].  derlying inflammation in neurodegeneration[J]. Cell,
                   Neuron,2016,91(2):328-340                         2010,140(6):918-934
             [72] ULLAND T K,SONG W M,HUANG S C C,et al. TREM2  [84] VOLONTÉ C,APOLLONI S,PARISI C,et al. Purinergic
                   maintains microglial metabolic fitness in Alzheimer’s  contribution to amyotrophic lateral sclerosis[J]. Neuro⁃
                   disease[J]. Cell,2017,170(4):649-663              pharmacology,2016,104:180-193
             [73] ULLAND T K,COLONNA M. TREM2⁃a key player in mi⁃  [85] YANG F,WANG Z Y,WEI X B,et al. NLRP3 deficiency
                   croglial biology and Alzheimer disease[J]. Nat Rev Neu⁃  ameliorates neurovascular damage in experimental ische ⁃
                   rol,2018,14(11):667-675                           mic stroke[J]. J Cereb Blood Flow Metab,2014,34(4):
             [74] PIERS T M,COSKER K,MALLACH A,et al. A locked       660-667
                   immunometabolic switch underlies TREM2 R47H loss of  [86] PERERA N D,TURNER B J. AMPK signalling and defec⁃
                   function in human iPSC⁃derived microglia[J]. FASEB J,  tive energy metabolism in amyotrophic lateral sclerosis
                   2020,34(2):2436-2450                             [J]. Neurochem Res,2016,41(3):544-553
             [75] MILLS E L,KELLY B,LOGAN A,et al. Succinate dehy⁃  [87] TSAI J M,SINHA R,SEITA J,et al. Surgical adhesions
                   drogenase supports metabolic repurposing of mitochon⁃  in mice are derived from mesothelial cells and can be tar⁃
                   dria to drive inflammatory macrophages[J]. Cell,2016,  geted by antibodies against mesothelial markers[J]. Sci
                   167(2):457-470                                    Transl Med,2018,10(469):eaan6735
             [76] VENEGAS C,KUMAR S,FRANKLIN B S,et al. Microg⁃  [88] BALDWIN A G,BROUGH D,FREEMAN S. Inhibiting
                   lia⁃derived ASC specks cross⁃seed amyloid⁃β in Alzhei⁃  the inflammasome:a chemical perspective[J]. J Med
                   mer’s disease[J]. Nature,2017,552(7685):355-361   Chem,2016,59(5):1691-1710
             [77] GOMEZ PERDIGUERO E,KLAPPROTH K,SCHULZ C,      [89] MEISSNER F,MOLAWI K,ZYCHLINSKY A. Mutant su⁃
                   et al. Tissue⁃resident macrophages originate from yolk⁃sac⁃  peroxide dismutase 1⁃induced IL⁃1beta accelerates ALS
                   derived erythro ⁃ myeloid progenitors[J]. Nature,2015,  pathogenesis[J]. Proc Natl Acad Sci USA,2010,107
                   518(7540):547-551                                (29):13046-13050
             [78] NAKAHIRA K,HASPEL J A,RATHINAM V A K,et al.   [90] MARTINEZ J,ALMENDINGER J,OBERST A,et al. Mi⁃
                   Autophagy proteins regulate innate immune responses by  crotubule⁃associated protein 1 light chain 3 alpha(LC3)⁃
                   inhibiting the release of mitochondrial DNA mediated by  associated phagocytosis is required for the efficient clea⁃
                   the NALP3 inflammasome[J]. Nat Immunol,2011,12    rance of dead cells[J]. Proc Natl Acad Sci U S A,2011,
                  (3):222-230                                        108(42):17396-17401
             [79] ROSTAMI J,HOLMQVIST S,LINDSTRÖM V,et al. Hu⁃  [91] VAN DEN BOSSCHE J,BAARDMAN J,OTTO N A,et
                   man astrocytes transfer aggregated alpha ⁃ synuclein via  al. Mitochondrial dysfunction prevents repolarization of
                   tunneling nanotubes[J]. J Neurosci,2017,37(49):   inflammatory macrophages[J]. Cell Rep,2016,17(3):
                   11835-11853                                       684-696
             [80] QIAO H F,HE X J,ZHANG Q J,et al. Alpha⁃synuclein  [92] PARK J,CHOI H,MIN J S,et al. Loss of mitofusin 2
                   induces microglial migration via PKM2⁃dependent glyco⁃  links beta⁃amyloid⁃mediated mitochondrial fragmentation
                   lysis[J]. Int J Biol Macromol,2019,129:601-607    and Cdk5⁃induced oxidative stress in neuron cells[J]. J
             [81] HUANG Y,XU Z,XIONG S,et al. Repopulated microglia  Neurochem,2015,132(6):687-702
                   are solely derived from the proliferation of residual mi⁃  [93] DU L,ZHANG Y,CHEN Y,et al. Role of microglia in
                   croglia after acute depletion[J]. Nat Neurosci,2018,21  neurological disorders and their potentials as a therapeu⁃
                  (4):530-540                                        tic target[J]. Mol Neurobiol,2017,54(10):7567-7584
             [82] LIANG J,LUO W,YU K,et al. Multi⁃omics revealing the  [94] GAO H M,HONG J S. Gene⁃environment interactions:
                   response patterns of symbiotic microorganisms and host  key to unraveling the mystery of Parkinson’s disease[J].
                   metabolism in scleractinian coral Pavona minuta to tem⁃  Prog Neurobiol,2011,94(1):1-19
                   perature stresses[J]. Metabolites,2021,12(1):18                        [收稿日期] 2023-07-25
             [83] GLASS C K,SAIJO K,WINNER B,et al. Mechanisms un⁃                             (本文编辑:蒋      莉)
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