Page 64 - 南京医科大学自然版
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第44卷第10期
·1380 · 南 京 医 科 大 学 学 报 2024年10月
表2 基于心脏MRI的室间隔各区域的瘢痕特征
Table 2 Characteristics of ventricular septal scars based on cardiac MRI [M(P25,P75)]
Scar burden(%) Scar quality(g) Scar scores
Success Failure Success Failure Success Failure
AHA segments
group group P group group P group group P
(n=44) (n=8) (n=44) (n=8) (n=44) (n=8)
Basal superior ventricular septum 6.50 22.50 0.21 0.00 1.50 0.39 0.5 0.75 0.06
(AHA 2) (0,1.00) (0.50,40.75) (0,1.0) (1.5,2.0) (0.5,0.5) (0.5,1.0)
Basal inferior ventricular septum 4.50 8.5 0.04 0.00 0.00 0.74 0.5 0.50 0.48
(AHA 3) (1.0,10.0)(0.75,19.25) (0.0,0.0) (0.0,0.75) (0.5,0.5) (0.5,1.25)
Middle superior ventricular septum 3.50 9.5 0.08 0.00 0.50 0.11 0.5 0.50 0.15
(AHA 8) (1.25,8.0) (2.25,22.0) (0.0,0.0)(0.00,0.89) (0.5,0.5) (0.5,0.5)
Middle inferior ventricular septum 4.00 5.0 0.26 0.00 0.00 0.59 0.0 0.50 0.04
(AHA 9) (0.25,10.75)(3.0,24.75) (0.0,1.0) (0.0,1.75) (0.5,0.5)(0.5,0.875)
Apical interventricular septum 0.00 9.5 0.10 0.00 1.00 0.30 0.5 0.50 0.23
(AHA 14) (0.0,7.75)(0.25,18.75) (0.0,1.0) (0.0,2.75) (0.0,0.5) (0.5,0.5)
Basal interventricular septum 6.84 16.12 0.25 0.39 0.84 0.73 1.0 1.25 0.13
(AHA 2+3) (1.98,13.93)(1.11,38.50) (0.14,1.05)(0.07,1.47) (1.0,1.0)(1.0,1.875)
Middle ventricular septum 4.75 06.84 0.13 0.53 0.70 0.19 1.0 1.00 0.06
(AHA 8+9) (0.99,8.67)(2.92,24.00) (0.22,1.00)(0.35,2.26) (1.0,1.0)(1.0,1.375)
Upper ventricular septum 6.76 16.24 0.06 0.58 1.20 0.13 1.0 1.50 0.05
(AHA 2+8) (2.51,11.16)(4.12,29.42) (0.19,1.15)(0.36,1.99) (0.625,1.0)(1.0,1.5)
Inferior ventricular septum 4.58 07.10 0.19 0.52 0.66 0.39 1.0 1.00 0.18
(AHA 3+9) (2.44,9.98)(4.83,16.99) (0.22,1.09)(0.31,1.84) (1.0,1.0) (1.0,1.0)
Septum except apex 6.50 12.00 0.08 1.00 2.00 0.18 2.0 2.50 0.06
(AHA 2+8+3+9) (2.0,10.75)(4.25,28.40) (0.25,2.0)(1.0,3.75) (1.5,2.0)(2.0,2.875)
Septum 5.85 07.19 0.45 1.63 2.23 0.76 1.0 0.80 0.08
(AHA 2+8+3+9+14) (1.1,8.91)(3.28,10.66) (0.79,4.89)(0.37,8.59) (1.0,1.0) (0.15,1.0)
Scoring criteria:scar scores for various parts of the interventricular septum were calculated using a 5⁃point scale(0:no LGE;1:1%-25% LGE;2:
26%-50% LGE;3:51%-75% LGE;4:76%-100% LGE);Calculate the average score for multiple segments(with a maximum score of 4).
表3 左心室功能参数及瘢痕评分单因素及多因素回归结果
Table 3 Univariate and multivariate regression results of functional parameters and scar scores in different segments of the
ventricular septum
Univariate Multivariate
Left ventricular functional parameters
OR 95%CI P OR 95%CI P
SVI(mL/m ) 0.877 0.796-0.966 0.01 - - -
2
2
CI[L/(min∙m )]AHA segments 0.181 0.041-0.809 0.03 - - -
Basal superior ventricular septum(AHA 2) 2.840 0.985-8.188 0.05 - - -
Middle inferior ventricular septum(AHA 9) 3.312 0.793-13.832 0.09 - - -
Middle ventricular septum(AHA 8+9) 1.819 0.888-3.727 0.10 - - -
Upper ventricular septum(AHA 2+8) 3.056 1.121-8.328 0.03 3.056 1.121-8.328 0.03
Septum except apex(AHA 2+8+3+9) 1.768 0.940-3.325 0.08 - - -
Septum(AHA 2+8+3+9+14) 0.189 0.030-1.169 0.07 - - -
For the sake of brevity,the univariate regression analysis in the table only listed the parameters of P≤0.01,and multivariate regression analysis
was performed based on this result.
负荷以及瘢痕评分进行评估。LGE 作为评判心肌 评估后可以根据纤维化程度筛选出适合LBBP的患
纤维化的金标准,在对心肌瘢痕进行准确的定位与 者 [12-13] 。既往研究表明,通过 CMR 评估心肌瘢痕质

