Page 73 - 南京医科大学自然版

第45卷第2期 陆 遥，邵文慧，宋佳成，等. 基于多参数磁共振的影像组学特征一致性聚类与早期宫颈癌临床及
2025年2月 组织病理学特征的相关性研究［J］. 南京医科大学学报（自然科学版），2025，45（2）：208-217 ·213 ·

A B C

D E F
59⁃year⁃old woman in cluster 1 with preoperative stage IB2 cervical cancer and an MRI⁃detected tumor size of（25 mm×17 mm×17 mm）（long
2
diameter×short diameter×height）. A：Axial T2WI shows a regular lesion（arrow）. B：On DWI（b value=1 000 s/mm ），the lesion shows high signal density
（arrow）. C，D：Lesion depicts decreased values on ADC map（C）and CE⁃T1WI（D）. E：Sagittal view shows shallow cervical stromal invasion（arrow）. F：
Coronary fat⁃suppressed T2WI showes no apparent node. Postoperative pathological examination confirmed stage IB2 squamous cervical cancer with
shallow（<1/3）stromal invasion，negative LNM and a tumor size of（27 mm×12 mm×5 mm）（long diameter × short diameter × height）.
图3 组1中的肿瘤具有较低临床及组织病理高危因素的典型病例
Figure 3 Typical case of a tumor in cluster 1 with lower risk clinical and histopathological high⁃risk factors

A B C

D E F
56⁃year⁃old woman in cluster 2 with preoperative stage IB3 cervical cancer and an MRI⁃detected tumor size of（48 mm×23 mm×25 mm）（long di⁃
2
ameter × short diameter × height）. A：Axial T2WI shows an irregular lesion（arrow）. B：On DWI（b value=1 000 s/mm ），the lesion shows a high signal
density（arrow）. C，D：Lesion depicts decreased values on ADC map（C）and CE⁃T1WI（D）. E：Sagittal view shows deep cervical stromal invasion（ar⁃
row）. F：Coronary fat⁃suppressed T2WI shows the left pelvic lymph node with the short axis of 5.5 mm（arrow）. Postoperative pathological examination
confirmes stage ⅢC1p squamous cervical cancer with deep（>2/3）stromal invasion，pelvic LNM and a tumor size of（46 mm×35 mm×16 mm）（long di⁃
ameter × short diameter × height）.
图4 组2中的肿瘤具有较高临床及组织病理高危因素的典型病例
Figure 4 Typical case of a tumor in cluster 2 with higher risk clinical and histopathological high⁃risk factors

更大的肿瘤直径。基于盆腔淋巴结的无监督聚类 放射组学作为一种非侵入性方法已经逐步应
分析没有发现两组之间的差异性。 用于宫颈癌组织病理学预后因素、治疗反应、肿瘤