Page 162 - 南京医科大学自然版

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·1060 · 南 京 医 科 大 学 学 报 2025年7月

A B C
CT and MRI revealed a neoplasm in the right maxillary sinus（red arrows）. A：Bone window axial. B：Soft tissue window axial. C：T2WI coronal position.
图1 患者2019年8月术前CT及MR影像
Figure 1 Preoperative CT and MRI images of the patient in August 2019

A B C
CT and MRI showing neoplasm in the posterior wall of the right maxillary sinus near the pterygopalatine fossa（red arrows）. A：Bone window coro⁃
nal. B：Soft tissue window axial. C：T2WI coronal.
图2 患者2023年7月复诊期间CT及MR影像
Figure 2 CT and MRI images during the follow⁃up examination of the patient in July 2023

Tumor cells showed solid nested infiltrative growth，consisting of MYB breakage probe FISH assay，MYB gene breakage（white ar⁃
basal ⁃ like cells（red arrow）and epithelioid cells（green arrow），with rows）was visible in tumor cells，with a breakage rate of approximately
rounded nuclei of medium size，cytoplasmic translucency of some cells 60%.
图4
in the non⁃glandular luminal surfaces，a few nuclear divisions were seen MYB断裂探针FISH检测
（black arrow），foci accompanied by the formation of ductal⁃like struc⁃ Figure 4 FISH detection images of MYB break probe
tures，and vitreous degeneration in some areas of the extra⁃tumoral mes⁃
enchyme，and mucinous degeneration in some areas（yellow arrow，×
性肿瘤的临床表现通常不典型，包括鼻塞、鼻衄，体
200）. 积大者可引起上颌部疼痛、面部膨隆、硬腭隆起
图3 患者2023年7月术后病理检查结果（HE×200）
Figure 3 Postoperative pathology result of the patient in 等。而 ACC 的特点在于其惰性生长和非特异性的
早期症状，这导致早期诊断困难 。此外 ACC 是一
［3］
July 2023（HE ×200）
种持续生长的肿瘤，具有嗜神经侵袭性，易发生周
［1］
筛窦，蝶窦和额窦的肿瘤极为罕见。鼻腔鼻窦ACC 围侵犯和多次局部复发 。常出现神经症状如颌面
［1］
约占鼻腔鼻窦恶性肿瘤的 4%~5% 。鼻腔鼻窦恶 部麻木或疼痛，视力下降等 ［4-5］ 。本例患者早期因鼻