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Journal of Nanjing Medical University
（Natural Sciences）
Contents of Main Articles
No.8 Vol.42 Aug. 2022
The optimized strategies for detecting interactions between membrane receptor and extracellular ligand using
fluorescence resonance energy transfer（FRET）technology
…………………………………………… MA Tingzheng，CAO Pingping，WANG Xuchun，SUN Yujie（1049）
Shikonin exerts neuroprotective effects by anti⁃oxidative stress and inhibiting inflammation after brain trauma
……………………ZHU Haiyan，ZHAO Xiaojing，SONG Jingjing，ZHANG Zhiyuan，WANG Xiaoliang（1055）
Whole genome sequencing and comparative genomics analysis of Escherichia coli J2_5
………………………………………………………ZHI Yaru，ZHANG Ying，YU xinyan，LIU Xiaoqiu（1065）
Identification of nuclear localization signal of vitamin D receptor（VDR） ……… MA Zemeng，CHEN Yunzi（1073）
Protective effect of TIR/BB⁃loop mimetic AS⁃1 on renal ischemia/reperfusion injury in mice
………………… DIAO Aiqin，ZHANG Guangji，WANG Hui，PAN Aiping，YUAN Haijian，LI Jiantao（1080）
STAT3⁃activated thrombospondin⁃4 induces apoptosis and inflammatory response in podocytes
……………………………………………………………ZHUANG Yibo，YANG Yong，NING Jingjing（1087）
Neurotoxicity of methamphetamine：a proteomic study of targeted synaptic damage
…………………………………………………… PENG Peng，XIE Cuiwei，WANG Jun，XIAO Hang（1093）
Prelimnary study one the role of lncRNA in osteoporosis
………………………………… LI Beichen，XU Fangrong，YANG Chongzheng，LIU Heng，SUN Qiang（1100）
Establishment and preliminary application of the immune⁃deficient mice models with Prkdc/Il2rg knockout
……………… YIN Yuan，ZENG Wentao，ZHOU Jianli，MEI Yun，WANG Ying，LI Jianmin，LAI Yana（1107）
The expression of circular RNA hsa_circ_0005579 in the placenta of patients with preeclampsia and its effect on
the proliferation，migration and invasion of trophoblast cells
…………………………………… GAO Mingming，YU Zhaoer，YAO Dan，ZHONG Hong，JIA Ruizhe（1112）
Detection of tumor driver gene TP53 R248W by CRISPR/Cas13a
……………………… KUANG Zhenzhan，XIAO Bin，SUN Zhaohui，LUO Rong，HE Jiewen，LI Linhai（1119）
The study of clinical features and gut microbiome of newly diagnosed type 2 diabetes patients with hyperuricemia
……………………… CHEN Rourou，LI Na，HE Rongbo，ZOU Jing，LIU Qing，ZHANG Ying，LIU Yu（1125）
