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第45卷第10期                 范 亮,肖心儒,张 倩. 乙酰化脯氨酸⁃甘氨酸⁃脯氨酸与肺部疾病[J].
                 2025年10月                    南京医科大学学报(自然科学版),2025,45(10):1528-1536                      ·1535 ·


                    of exposure in users of classic cigarettes,E ⁃ cigarettes,  chronic obstructive pulmonary disease[J]. Am J Respir
                    and heated tobacco products⁃a narrative review[J]. Int J  Crit Care Med,2015,192(8):934-942
                    Mol Sci,2025,26(5):1796                      [31]O’REILLY P,JACKSON P L,NOERAGER B,et al. N⁃
               [19]HARDISON M T,BROWN M D,SNELGROVE R J,et al.         alpha⁃PGP and PGP,potential biomarkers and therapeutic
                    Cigarette smoke enhances chemotaxis via acetylation of  targets for COPD[J]. Respir Res,2009,10(1):38
                    proline⁃glycine⁃proline[J]. Front Biosci(Elite Ed),2012,  [32]SETLAKWE E L,LEMOS K R,LAVOIE⁃LAMOUREUX
                    4(7):2402-2409                                     A,et al. Airway collagen and elastic fiber content corre⁃
               [20]JACKSON P L,NOERAGER B D,JABLONSKY M J,et           lates with lung function in equine heaves[J]. Am J Physi⁃
                    al. A CXCL8 receptor antagonist based on the structure of  ol Lung Cell Mol Physiol,2014,307(3):L252-L260
                    N⁃acetyl⁃proline⁃glycine⁃proline[J]. Eur J Pharmacol,  [33] RÖHN T A,NUMAO S,OTTO H,et al. Drug discovery
                    2011,668(3):435-442                                strategies for novel leukotriene A4 hydrolase inhibitors
               [21]LAZENNEC G,RAJARATHNAM K,RICHMOND A. CX⁃           [J]. Expert Opin Drug Discov,2021,16(12):1483-1495
                    CR2 chemokine receptor⁃a master regulator in cancer and  [34] SHARMA N S,LAL C V,LI J D,et al. The neutrophil
                    physiology[J]. Trends Mol Med,2024,30(1):37-55     chemoattractant peptide proline⁃glycine⁃proline is associ⁃
               [22] XIE Y S,KUANG W B,WANG D W,et al. Expanding        ated with acute respiratory distress syndrome[J]. Am J
                    role of CXCR2 and therapeutic potential of CXCR2 antag⁃  Physiol Lung Cell Mol Physiol,2018,315(5):L653-
                    onists in inflammatory diseases and cancers[J]. Eur J  L661
                    Med Chem,2023,250:115175                     [35] LI X H,XIE M D,LU C,et al. Design and synthesis of
               [23]KIM S D,LEE H Y,SHIM J W,et al. Activation of CX⁃   leukotriene A4 hydrolase inhibitors to alleviate idiopathic
                    CR2 by extracellular matrix degradation product acetylated  pulmonary fibrosis and acute lung injury[J]. Eur J Med
                    Pro⁃Gly⁃Pro has therapeutic effects against sepsis[J]. Am  Chem,2020,203:112614
                    J Respir Crit Care Med,2011,184(2):243-251   [36]SUVEIZDYTE K,PATEL D F,PYLE C J,et al. OverZeal⁃
               [24] KWON Y W,HEO S C,LEE T W,et al. N⁃acetylated       ous degradation of collagen fragment Pro ⁃ Gly ⁃ Pro by
                    proline ⁃ glycine ⁃ proline accelerates cutaneous wound  leukotriene A4 hydrolase(LTA4H)perpetuates fibrosis in
                    healing and neovascularization by human endothelial  IPF[C]//Mechanisms of Lung Injury and Repair. Europe⁃
                    progenitor cells[J]. Sci Rep,2017,7:43057          an Respiratory Society,2022:127
               [25]PATEL D F,PEIRÓ T,SHOEMARK A,et al. An extracel⁃  [37]PROBST C K,MONTESI S B,MEDOFF B D,et al. Vas⁃
                    lular matrix fragment drives epithelial remodeling and  cular permeability in the fibrotic lung[J]. Eur Respir J,
                    airway hyperresponsiveness[J]. Sci Transl Med,2018,10  2020,56(1):1900100
                   (455):eaaq0693                                [38]KREUTER M,LEDERER D J,MOLINA⁃MOLINA M,et
               [26]RODA M A,XU X,ABDALLA T H,et al. Proline⁃glycine⁃   al. Association of angiotensin modulators with the course
                    proline peptides are critical in the development of smoke⁃  of idiopathic pulmonary fibrosis[J]. Chest,2019,156
                    induced emphysema[J]. Am J Respir Cell Mol Biol,  (4):706-714
                    2019,61(5):560-566                           [39]AWAJI M,SAXENA S,WU L Y,et al. CXCR2 signaling
               [27] LIAO S X,WANG Y W,SUN P P,et al. Prospects of      promotes secretory cancer ⁃ associated fibroblasts in
                     neutrophilic implications against pathobiology of chronic  pancreatic ductal adenocarcinoma[J]. FASEB J,2020,34
                     obstructive pulmonary disease:pharmacological insights  (7):9405-9418
                     and technological advances[J]. Int Immunopharmacol,  [40] KIM H,JANG Y,RYU J,et al. The dipeptide gly ⁃ pro
                     2025,144:113634                                  (GP),derived from Hibiscus sabdariffa,exhibits potent
               [28]CHRISTOPOULOU M E,PAPAKONSTANTINOU E,               antifibrotic effects by regulating the TGF⁃ β 1⁃ATF4⁃
                    STOLZ D. Matrix metalloproteinases in chronic obstruc⁃  serine/glycine biosynthesis pathway[J]. Int J Mol Sci,
                    tive pulmonary disease[J]. Int J Mol Sci,2023,24(4):3786  2023,24(17):13616
               [29]WELLS J M,XING D Q,VIERA L,et al. The matrikine  [41]MCKELVEY M C,BROWN R,RYAN S,et al. Proteases,
                    acetyl ⁃ proline ⁃ glycine ⁃ proline and clinical features of  mucus,and mucosal immunity in chronic lung disease[J].
                    COPD:findings from SPIROMICS[J]. Respir Res,2019,  Int J Mol Sci,2021,22(9):5018
                    20(1):254                                    [42]CWILICHOWSKA N, SWIDERSKA K W,DOBRZYN A,
               [30]WELLS J M,JACKSON P L,VIERA L,et al. A random⁃      et al.Diagnostic and therapeutic potential of protease
                    ized,placebo ⁃ controlled trial of roflumilast.effect on  inhibition[J]. Mol Aspects Med,2022,88:101144
                    proline⁃glycine⁃proline and neutrophilic inflammation in  [43]NICOLA T,WENGER N,XU X,et al. A lactobacilli ⁃
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