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Cluster period： N
2020/1/1—2020/12/31
P < 0.001 Ganyu
Fengxian
Peixian
Cluster period：
Haizhou
Donghai Lianyun
2010/1/1—2012/6/30
Jiawang Pizhou P < 0.001
Guanyun
Gulou
Quanshan Xinyi
Yunlong Xiangshui
Tongshan Shuyang Guannan
Binhai
Suyu
Suining
Lianshui
Sucheng Sheyang
Siyang Huaiyin Funing
Cluster period：
2012/8/1—2017/2/28 Qingjiangpu Huaian Jianhu
P < 0.001 Sihong Tinghu
Yandu
Hongze Baoying
Dafeng
Cluster period：
Jinhu
Xinghua 2014/11/1—2019/12/31
Xuyu P < 0.001
Gaoyou Dongtai
No cluster
First cluster
Jiangdu Haian
Second cluster⁃1 Hanjiang HailingJiangyan
Liuhe Rudong
Second cluster⁃2 Yizheng Guangling Gaogang
Rugao
Second cluster⁃3 Runzhou Dantu Taixing
Qixia Jingkou Yangzhong
Gulou Runzhou Tongzhou
Second cluster⁃4 Pukou Eant
Jianye Xtianwu Jingjiang Chongchuan
Second cluster⁃5 Yuhuatni Jurong Danyang Xinbei Zhangjiagang Haimen
Jiangning Jiangyin Qidong
Zhonglou Tianning
Jintan
Wujin Huishan Xishan Changshu
Lishui Liangxi
Cluster period： Xinwn Taicang
Liyang Binhu Xiangcheng
2020/7/1—2020/12/31
0 30 60 120 miles Yixing Huqiu Gusn Kunshan
P < 0.001 Gaochun Cluster period：
HuqruHuaiu
Wuzhong 2017/3/1—2019/3/31
Wujiang P < 0.001
图4 江苏省13个设区市2010—2024年HBV⁃ASIR的时空分布
Figure 4 Spatiotemporal distribution of HBV⁃ASIR in Jiangsu from 2010 to 2024
000） 60 All age Male 000） 60 <30 years Male 000） 60 30-<50 years Male
50
50
50
Female
Female
Female
All
All
All
40
40
40
ASIR （1/100 30 ASIR （1/100 30 ASIR （1/100 30
20
20
20
10
0 10 0 10 0
2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Year Year Year
000） 60 50-<70 years Male 000） 60 ≥70 years Male
50
50
Female
Female
All
All
40
40
ASIR （1/100 30 ASIR （1/100 30
20
20
10
0 10 0
2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Year Year
图5 2010—2024年江苏省全人群及4个年龄组（<30岁、30~<50岁、50~<70岁和≥70岁）HBV⁃ASIR的时间趋势
Figure 5 Temporal trends of HBV⁃ASIR for all ages and four age groups（<30，30-<50，50-<70 and ≥70 years）in Jiangsu
from 2010 to 2024