Page 100 - 《南京医科大学学报》自然科学版2026年第2期
P. 100
南京医科大学学报(自然科学版) 第46卷第2期
·256 · Journal of Nanjing Medical University(Natural Sciences) 2026年2月
·临床研究·
胆囊十二指肠瘘伴胆石性肠梗阻19例诊治分析
李 番 ,王一鸣 ,周浩明 ,饶建华 ,姚爱华 ,成 峰 ,倪 鸣 ,吕 凌 1*
1
1
2
1
1
1
1
南京医科大学第一附属医院肝胆中心,江苏 南京 210029;北京协和医院肝胆外科,北京 100032
1 2
[摘 要] 目的:探讨胆囊十二指肠瘘合并胆石性肠梗阻的诊断、治疗及预后。方法:回顾性分析南京医科大学第一附属医院
2019年10月—2024年10月收治的19例胆囊十二指肠瘘合并胆石性肠梗阻患者的临床资料。结果:19例患者中男9例,女10例,
中位年龄76岁,均因腹部胀痛就诊,既往均有胆石症病史数年。所有患者经影像学确诊后根据结石及患者情况采取肠道切开
取石术以及一期或二期胆囊切除和胆囊十二指肠瘘修补术。术后2例出现切口感染,其余均治愈出院,无死亡病例发生。结
论:胆囊十二指肠瘘合并胆石性肠梗阻较为罕见,临床表现复杂,常合并多种并发症,围手术期风险较高,应根据患者病情选择
个性化的治疗方案。
[关键词] 胆囊十二指肠瘘;胆石性肠梗阻;诊断;个性化治疗
[中图分类号] R656.64 [文献标志码] A [文章编号] 1007⁃4368(2026)02⁃256⁃06
doi:10.7655/NYDXBNSN251004
Diagnosis and treatment analysis of 19 cases of cholecystoduodenal fistula with gallstone
ileus
1
1
1
1
1
1
2
LI Fan ,WANG Yiming ,ZHOU Haoming ,RAO Jianhua ,YAO Aihua ,CHENG Feng ,NI Ming ,LÜ Ling 1*
1 Hepatobiliary Center,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029;Department of
2
Liver Surgery,Peking Union Medical College Hospital,Beijing 100032,China
[Abstract] Objective:To investigate the diagnosis,treatment,and prognosis of cholecystoduodenal fistula complicated with
gallstone ileus. Methods:This study retrospectively analyzed clinical data from 19 patients with cholecystoduodenal fistula and
gallstone ileus treated at the First Affiliated Hospital of Nanjing Medical University from October 2019 to October 2024. Results:
Among the 19 patients,9 were male and 10 were female,with a median age of 76 years. All patients presented with abdominal
distension and pain,with a history of cholelithiasis spanning several years. After imaging confirmation,individualized surgical
approaches—including enterolithotomy,single ⁃ or two ⁃ stage cholecystectomy,and fistula repair—were performed based on stone
characteristics and patient status. Postoperatively,two cases developed incision infections,while all others recovered and were
discharged without mortality. Conclusion:Cholecystoduodenal fistula with gallstone ileus is relatively rare,manifests with complex
presentations,often involves multiple complications,and carries high perioperative risks. Personalized treatment strategies should be
tailored to individual patient conditions.
[Key words] cholecystoduodenal fistula;gallstone ileus;diagnosis;individualized treatment
[J Nanjing Med Univ,2026,46(02):256⁃261]
胆囊肠瘘是慢性胆囊炎伴胆囊结石相对罕见 石性肠梗阻是胆道结石通过胆囊肠瘘进入肠道引
[1]
的并发症,其中胆囊十二指肠瘘占75%~80% 。胆 起的,是机械性肠梗阻中的罕见类型,然而病死率
却很高(12%~27%),远高于其他类型 。胆囊十二
[2]
指肠瘘合并胆石性肠梗阻患者多为老年人且合并
[基金项目] 中国医学科学院创新单元项目(2019⁃I2M⁃5⁃035)
多种并发症,围手术期风险较高,应根据患者的病
∗
通信作者(Corresponding author),E⁃mail:lvling@njmu.edu.cn
(ORCID:0000⁃0002⁃4983⁃5557) 情选择合适的治疗方式。本研究回顾性分析南京

