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第42卷第11期
               ·1614 ·                           南 京    医 科 大 学 学         报                        2022年11月


             ·公共卫生与预防医学研究·

              江苏省 SARS⁃CoV⁃2 Omicron 变异株引起的新型冠状病毒肺炎

              流行病学特征分析



              何 薇 ,俞飞超 ,魏艳秋 ,孙             伟 ,任登华 ,吴桢珍 ,冯旰珠 ,吉宁飞 ,王新民 ,黄 茂                    1*
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               南京医科大学第一附属医院呼吸与危重症医学科,江苏                     南京    210029;无锡市锡山人民医院呼吸与危重症医学科,江苏
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              无锡    214105;南京医科大学第二附属医院呼吸与危重症医学科,江苏                     南京    210003;沭阳县中医院呼吸与危重症医学
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              科,江苏 宿迁 223699
             [摘    要] 目的:分析江苏省由新型冠状病毒即严重急性呼吸综合征冠状病毒2型(severe acute respiratory syndrome coronavi⁃
              rus 2,SARS⁃CoV⁃2)Omicron变异株引起的新型冠状病毒肺炎(coronavirus disease 2019,COVID⁃19)的流行病学特征,为后续疫
              情的防控措施提供数据支持。方法:收集江苏省卫生健康委员会官网以及各市政府官方通报(2022年2月13日—4月9日)的
              COVID⁃19病例数据并进行流行病学调查研究。结果:截至2022年4月9日,江苏省SARS⁃CoV⁃2 Omicron变异株引起的COVID
              ⁃19疫情蔓延势头初步遏制,累积发病率为0.48/10万,病死率为0。无症状感染者比例高(76.3%),确诊病例中以轻型为主。发病
              中位年龄为42岁,<20岁感染者占16.9%。OmicronBA.1变异株中位潜伏期为5.0(4.5,6.0)d,BA.2变异株中位潜伏期为3.0(2.8,
              3.5)d,两组潜伏期差异有统计学意义(P<0.05)。聚集性病例比例较高(81.6%),主要来自家庭聚集。结论:Omicron变异株传染
              性强,潜伏期短,毒力减弱,该阶段江苏省Omicron感染病死率为0,江苏省实施的精准防控成果显著。
             [关键词] Omicron变异株;新型冠状病毒肺炎;江苏省;流行病学特征
             [中图分类号] R181.8                   [文献标志码] A                       [文章编号] 1007⁃4368(2022)11⁃1614⁃07
              doi:10.7655/NYDXBNS20221119


              Epidemiology of infections with SARS⁃CoV⁃2 Omicron variant in Jiangsu Province,China

              HE Wei ,YU Feichao ,WEI Yanqiu ,SUN Wei ,REN Denghua ,WU Zhenzhen ,FENG Ganzhu ,JI Ningfei ,
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              WANG Xinmin ,HUANG Mao
              1 Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Nanjing Medical University,
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              Nanjing 210029;Department of Respiratory and Critical Care Medicine,Xishan People’s Hospital of Wuxi City,
              Wuxi 214105;Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital of Nanjing
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              Medical University,Nanjing 210003;Department of Respiratory and Critical Care Medicine,Shuyang Hospital of
              Traditional Chinese Medicine,Suqian 223699,China
             [Abstract] Objective:This study aims to analyze the epidemiological characteristics of coronavirus disease 2019(COVID ⁃ 19)
              caused by severe acute respiratory syndrome coronavirus 2(SARS⁃CoV⁃2)Omicron variant and provide data support for prevention and
              control measures followed. Methods:The COVID⁃19 data during February 13,2022 to April 9,2022 were obtained from official website
              of Jiangsu Province Health Commission and municipal governments. Descriptive epidemiological methods were used to analyze the
              characteristics of cases. Results:As of April 9,2022,the spread of COVID⁃19 caused by SARS⁃CoV⁃2 Omicron variant in Jiangsu
              Province has been initially contained,with a cumulative incidence of 0.48/100 000 and a fatality rate of 0. It was characterized by a high
              proportion(76.3%)of asymptomatic patients,and most of the confirmed cases were mild. The median age was 42 years,and 16.9%
              infected individuals were under 20 years old. The median incubation period of Omicron BA.1 variant was 5.0(4.5,6.0)days,and that of
              BA.2 variant was 3.0(2.8,3.5)days,with significant difference(P<0.05). There was a high proportion of cluster cases(81.6%). Among
              them,the main type was family cluster. Conclusion:Omicron variant is highly infectious,with short incubation period and weakened


             [基金项目] 江苏省重点研发计划(BE2020616);宿迁市指导性科技计划(Z2021011)
              ∗
              通信作者(Corresponding author),E⁃mail:aaawxm110@163.com;hm6114@126.com
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