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第42卷第4期 蒋日月，邓 倾，周 青. 间充质干细胞来源外泌体治疗心肌梗死的研究进展［J］.
2022年4月 南京医科大学学报（自然科学版），2022，42（4）：588-594 ·593 ·

［23］ LIU B，LEE B W，NAKANISHI K，et al. Cardiac recovery ization［J］. Cardiovasc Res，2019，115（7）：1205-1216
via extended cell⁃free delivery of extracellular vesicles se⁃ ［34］ LUO Q，GUO D，LIU G，et al. Exosomes from MiR⁃126⁃
creted by cardiomyocytes derived from induced pluripo⁃ overexpressing adscs are therapeutic in relieving acute
tent stem cells［J］. Nat Biomed Eng，2018，2（5）：293-303 myocardial ischaemic injury［J］. Cell Physiol Biochem，
［24］ HUANG L，YANG L，DING Y，et al. Human umbilical 2017，44（6）：2105-2116
cord mesenchymal stem cells⁃derived exosomes transfers ［35］ DENG S，ZHOU X，GE Z，et al. Exosomes from adipose⁃
microRNA⁃19a to protect cardiomyocytes from acute myo⁃ derived mesenchymal stem cells ameliorate cardiac dam⁃
cardial infarction by targeting SOX6［J］. Cell Cycle， age after myocardial infarction by activating S1P/SK1/
2020，19（3）：339-353 S1PR1 signaling and promoting macrophage M2 polariza⁃
［25］ SUN X H，WANG X，ZHANG Y，et al. Exosomes of bone⁃ tion［J］. Int J Biochem Cell Biol，2019，114：105564
marrow stromal cells inhibit cardiomyocyte apoptosis un⁃ ［36］ XU R，ZHANG F，CHAI R，et al. Exosomes derived from
der ischemic and hypoxic conditions via miR⁃486⁃5p tar⁃ pro ⁃ inflammatory bone marrow ⁃ derived mesenchymal
geting the PTEN/PI3K/AKT signaling pathway ［J］. stem cells reduce inflammation and myocardial injury via
Thromb Res，2019，177：23-32 mediating macrophage polarization［J］. J Cell Mol Med，
［26］ SHI B，WANG Y，ZHAO R，et al. Bone marrow mesenchy⁃ 2019，23（11）：7617-7631
mal stem cell⁃derived exosomal miR⁃21 protects C⁃kit+ ［37］ CHAI H T，SHEU J J，CHIANG J Y，et al. Early adminis⁃
cardiac stem cells from oxidative injury through the tration of cold water and adipose derived mesenchymal
PTEN/PI3K/Akt axis［J］. PLoS One，2018，13（2）： stem cell derived exosome effectively protects the heart
e0191616 from ischemia⁃reperfusion injury［J］. Am J Transl Res，
［27］ WEN Z，MAI Z，ZHU X，et al. Mesenchymal stem cell⁃de⁃ 2019，11（9）：5375-5389
rived exosomes ameliorate cardiomyocyte apoptosis in hy⁃ ［38］ LOPATINA T，BRUNO S，TETTA C，et al. Platelet⁃de⁃
poxic conditions through microRNA144 by targeting the rived growth factor regulates the secretion of extracellular
PTEN/AKT pathway［J］. Stem Cell Res Ther，2020，11 vesicles by adipose mesenchymal stem cells and enhanc⁃
（1）：36 es their angiogenic potential［J］. Cell Commun Signal，
［28］ LIU L，JIN X，HU C F，et al. Exosomes derived from mes⁃ 2014，12：26
enchymal stem cells rescue myocardial ischaemia/reperfu⁃ ［39］ BIAN S，ZHANG L，DUAN L，et al. Extracellular vesicles
sion injury by inducing cardiomyocyte autophagy via derived from human bone marrow mesenchymal stem
AMPK and Akt pathways［J］. Cell Physiol Biochem， cells promote angiogenesis in a rat myocardial infarction
2017，43（1）：52-68 model［J］. J Mol Med（Berl），2014，92（4）：387-397
［29］ MAO Q，LIANG X L，ZHANG C L，et al. LncRNA KLF3⁃ ［40］ HUANG P，WANG L，LI Q，et al. Atorvastatin enhances
AS1 in human mesenchymal stem cell⁃derived exosomes the therapeutic efficacy of mesenchymal stem cells ⁃ de⁃
ameliorates pyroptosis of cardiomyocytes and myocardial rived exosomes in acute myocardial infarction via up⁃regu⁃
infarction through miR⁃138⁃5p/Sirt1 axis［J］. Stem Cell lating long non ⁃ coding RNA H19［J］. Cardiovasc Res，
Res Ther，2019，10（1）：393 2020，116（2）：353-367
［30］ PENG Y，ZHAO J L，PENG Z Y，et al. Exosomal miR⁃25⁃ ［41］ CHEN T，YAO L Q，SHI Q，et al. MicroRNA⁃31 contrib⁃
3p from mesenchymal stem cells alleviates myocardial in⁃ utes to colorectal cancer development by targeting factor
farction by targeting pro⁃apoptotic proteins and EZH2［J］. inhibiting HIF ⁃ 1alpha（FIH ⁃ 1）［J］. Cancer Biol Ther，
Cell Death Dis，2020，11（5）：317 2014，15（5）：516-523
［31］ CHENG H，CHANG S，XU R，et al. Hypoxia⁃challenged ［42］ BARILE L，LIONETTI V，CERVIO E，et al. Extracellular
MSC⁃derived exosomes deliver miR⁃210 to attenuate post⁃ vesicles from human cardiac progenitor cells inhibit car⁃
infarction cardiac apoptosis［J］. Stem Cell Res Ther， diomyocyte apoptosis and improve cardiac function after
2020，11（1）：224 myocardial infarction［J］. Cardiovasc Res，2014，103（4）：
［32］ FU D L，JIANG H，LI C Y，et al. MicroRNA⁃338 in MSCs⁃ 530-541
derived exosomes inhibits cardiomyocyte apoptosis in ［43］ ANAND S，MAJETI B K，ACEVEDO L M，et al. MicroR⁃
myocardial infarction［J］. Eur Rev Med Pharmacol Sci， NA⁃132⁃mediated loss of p120RasGAP activates the en⁃
2020，24（19）：10107-10117 dothelium to facilitate pathological angiogenesis［J］. Nat
［33］ ZHAO J，LI X，HU J，et al. Mesenchymal stromal cell⁃de⁃ Med，2010，16（8）：909-914
rived exosomes attenuate myocardial ischaemia ⁃ reperfu⁃ ［44］ RAU C S，YANG J C，CHEN Y C，et al. Lipopolysaccha⁃
sion injury through miR⁃182⁃regulated macrophage polar⁃ ride⁃induced microRNA⁃146a targets CARD10 and regu⁃