Page 122 - 南京医科大学学报自然科学版
P. 122
第42卷第6期
·874 · 南 京 医 科 大 学 学 报 2022年6月
后恢复的作用。 tourniquet:pathophysiological consequences and anaes⁃
本研究也存在一些局限。第一,未对利多卡因 thetic implications[J]. Anaesthesia,2001,56(6):534-
的血浆浓度进行动态监测。但根据一项静脉内应 545
用利多卡因的国际共识声明 [18] ,本研究使用的利多 [10] VALLI H,ROSENBERG P H,KYTTÄ J,et al. Arterial
卡因剂量引起局麻药中毒的可能性较小。第二,研 hypertension associated with the use of a tourniquet with
either general or regional anaesthesia[J]. Acta Anaesthe⁃
究中发现实验组的患者在术中仍然存在 TIH 现象,
siol Scand,1987,31(4):279-283
因此后续会继续探讨利多卡因在TIH预防和治疗中
[11] GUPTA K,AGGARWAL N,RAO M,et al. Re⁃emphasiz⁃
的最佳剂量。
ing the importance of tourniquet time:severe myocardial
随着日间手术的发展以及快速康复外科的成
depression following tourniquet deflation[J]. Acta Anaes⁃
熟,静脉内应用利多卡因可以发挥关键作用。本研
thesiol Scand,2008,52(6):873
究表明在使用止血带的膝关节镜手术中,静脉持续 [12] BEAUSSIER M,DELBOS A,MAURICE⁃SZAMBURSKI
输注低剂量利多卡因可以有效预防TIH。 A,et al. Perioperative use of intravenous lidocaine[J].
[参考文献] Drugs,2018,78(12):1229-1246
[13] ALLEE J,MUZAFFAR A R,TOBIAS J D. Dexmedetomi⁃
[1] SMITH T O,HING C B. Is a tourniquet beneficial in total
dine controls the hemodynamic manifestations of tourni⁃
knee replacement surgery?A meta⁃analysis and systematic
quet pain[J]. Am J Ther,2011,18(2):e35-e39
review[J]. Knee,2010,17(2):141-147
[14] HONARMAND A,SAFAVI M R. Preoperative oral dextro⁃
[2] KUMAR K,RAILTON C,TAWFIC Q. Tourniquet appli⁃
methorphan vs. clonidine to prevent tourniquet ⁃ induced
cation during anesthesia:“What we need to know?”[J]. J
cardiovascular responses in orthopaedic patients under
Anaesthesiol Clin Pharmacol,2016,32(4):424-430
general anaesthesia[J]. Eur J Anaesthesiol,2007,24(6):
[3] 刘元雪,李 峰,王艺丹,等. 无阿片药麻醉临床应用进
511-515
展[J]. 国际麻醉学与复苏杂志,2021,42(5):505-509
[15] YARDENI I Z,BEILIN B,MAYBURD E,et al. The effect
[4] SATSUMAE T,YAMAGUCHI H,SAKAGUCHI M,et al.
of perioperative intravenous lidocaine on postoperative
Preoperative small⁃dose ketamine prevented tourniquet⁃
pain and immune function[J]. Anesth Analg,2009,109
induced arterial pressure increase in orthopedic patients
under general anesthesia[J]. Anesth Analg,2001,92(5): (5):1464-1469
[16] LIU Y,ZHANG J,ZAN J,et al. Lidocaine improves cere⁃
1286-1289
[5] 王瑞玉,刘 尧,赵 伟,等. 硫酸镁对全麻下止血带相 bral ischemia ⁃ reperfusion injury in rats through cAMP/
PKA signaling pathway[J]. Exp Ther Med,2020,20(1):
关高血压和术后疼痛的影响[J]. 临床麻醉学杂志,
495-499
2019,35(7):676-679
[17] ARSYAD A,DOBSON G P. Lidocaine relaxation in isolat⁃
[6] HAMILL J F,BEDFORD R F,WEAVER D C,et al. Lido⁃
ed rat aortic rings is enhanced by endothelial removal:
caine before endotracheal intubation:intravenous or laryn⁃
possible role of K v,KATP channels and A2a receptor cross⁃
gotracheal?[J]. Anesthesiology,1981,55(5):578-581
[7] FOO I,MACFARLANE A J R,SRIVASTAVA D,et al. talk[J]. BMC Anesthesiol,2016,16(1):121
The use of intravenous lidocaine for postoperative pain [18] YAO Y,JIANG J,LIN W,et al. Efficacy of systemic lido⁃
and recovery:international consensus statement on efficacy caine on postoperative quality of recovery and analgesia
and safety[J]. Anaesthesia,2021,76(2):238-250 after video ⁃ assisted thoracic surgery:a randomized con⁃
[8] KAUFMAN R D,WALTS L F. Tourniquet⁃induced hyper⁃ trolled trial[J]. J Clin Anesth,2021,71:110223
tension[J]. Br J Anaesth,1982,54(3):333-336 [收稿日期] 2021-11-12
[9] KAM P C,KAVANAGH R,YOONG F F. The arterial (本文编辑:陈汐敏)