Page 136 - 南京医科大学学报自然科学版
P. 136
第42卷第9期
·1330 · 南 京 医 科 大 学 学 报 2022年9月
489 e417 of mitochondrial calcium revealed by mice lacking the mi⁃
[54] MASTROTOTARO L,SMORODCHENKO A,ASCHEN⁃ tochondrial calcium uniporter[J]. Nat Cell Biol,2013,15
BACH J R,et al. Solute carrier 41A3 encodes for a mito⁃ (12):1464-1472
chondrial Mg(2 +)efflux system[J]. Sci Rep,2016,6: [68] DE STEFANI D,RIZZUTO R,POZZAN T. Enjoy the trip:
27999 calcium in mitochondria back and forth[J]. Annu Rev
[55] CUI Y,ZHAO S,WANG X,et al. A novel Drosophila mi⁃ Biochem,2016,85:161-192
tochondrial carrier protein acts as a Mg(2+)exporter in [69] BAUER TM,MURPHY E. Role of mitochondrial calcium
fine⁃tuning mitochondrial Mg(2+)homeostasis[J]. Bio⁃ and the permeability transition pore in regulating cell
chim Biophys Acta,2016,1863(1):30-39 death[J]. Circ Res,2020,126(2):280-293
[56] KOLISEK M,ZSURKA G,SAMAJ J,et al. Mrs2p is an es⁃ [70] XU S,WANG P,ZHANG H,et al. CaMKⅡ induces per⁃
sential component of the major electrophoretic Mg2+ in⁃ meability transition through DRP1 phosphorylation dur⁃
flux system in mitochondria[J]. EMBO J,2003,22(6): ing chronic beta⁃AR stimulation[J]. Nat Commun,2016,
1235-1244 7:13189
[57] JI S G,MEDVEDEVA Y V,WEISS J H. Zn(2+)entry [71] DESPA S,ISLAM M A,WEBER C R,et al. Intracellular
through the mitochondrial calcium uniporter is a critical Na(+)concentration is elevated in heart failure but Na/K
contributor to mitochondrial dysfunction and neurodegen⁃ pump function is unchanged[J]. Circulation,2002,105
eration[J]. Exp Neurol,2020,325:113161 (21):2543-2548
2+
[58] MCDONAGH TA,METRA M,ADAMO M,et al. 2021 [72] LIU T,O’ROURKE B. Enhancing mitochondrial Ca up⁃
ESC guidelines for the diagnosis and treatment of acute take in myocytes from failing hearts restores energy sup⁃
and chronic heart failure[J]. Eur Heart J,2021,42(36): ply and demand matching[J]. Circ Res,2008,103(3):
3599-3726 279-288
[59] WU C,ZHANG Z,ZHANG W,et al. Mitochondrial dys⁃ [73] AKSENTIJEVIC D,KARLSTAEDT A,BASALAY M V,
function and mitochondrial therapies in heart failure[J]. et al. Intracellular sodium elevation reprograms cardiac
Pharmacol Res,2022,175:106038 metabolism[J]. Nat Commun,2020,11(1):4337
[60] HAUSENLOY D J,SCHULZ R,GIRAO H,et al. Mito⁃ [74] LIU T,TAKIMOTO E,DIMAANO V L,et al. Inhibiting mi⁃
+
2+
chondrial ion channels as targets for cardioprotection[J]. tochondrial Na /Ca exchange prevents sudden death in a
J Cell Mol Med,2020,24(13):7102-7114 Guinea pig model of heart failure[J]. Circ Res,2014,115
[61] XU H X,CUI S M,ZHANG Y M,et al. Mitochondrial (1):44-54
Ca(2+)regulation in the etiology of heart failure:physio⁃ [75] TUNCAY E,BITIRIM CV,OLGAR Y,et al. Zn(2 +)⁃
logical and pathophysiological implications [J]. Acta transporters ZIP7 and ZnT7 play important role in pro⁃
Pharmacol Sin,2020,41(10):1301-1309 gression of cardiac dysfunction via affecting sarco(endo)
[62] BERTERO E,MAACK C. Metabolic remodelling in heart plasmic reticulum ⁃ mitochondria coupling in hyperglyce⁃
failure[J]. Nat Rev Cardiol,2018,15(8):457-470 mic cardiomyocytes[J]. Mitochondrion,2019,44:41-52
[63] KLAPPER⁃GOLDSTEIN H,VERMA A,ELYAGON S,et [76] MAACK C,LEHRKE M,BACKS J,et al. Heart failure
al. VDAC1 in the diseased myocardium and the effect of and diabetes:metabolic alterations and therapeutic inter⁃
VDAC1⁃interacting compound on atrial fibrosis induced ventions:a state⁃of⁃the⁃art review from the translational
by hyperaldosteronism[J]. Sci Rep,2020,10(1):22101 research committee of the heart failure association⁃europe⁃
[64] WU Y,RASMUSSEN T P,KOVAL O M,et al. The mito⁃ an society of cardiology[J]. Eur Heart J,2018,39(48):
chondrial uniporter controls fight or flight heart rate in⁃ 4243-4254
creases[J]. Nat Commun,2015,6:6081 [77] WESTERMEIER F,RIQUELME J A,PAVEZ M,et al.
[65] LUONGO T S,LAMBERT J P,YUAN A,et al. The mito⁃ New molecular insights of insulin in diabetic cardiomyo⁃
chondrial calcium uniporter matches energetic supply pathy[J]. Front Physiol,2016,7:125
with cardiac workload during stress and modulates perme⁃ [78] HEGYI B,BERS D M,BOSSUYT J. CaMKⅡ signaling in
ability transition[J]. Cell Rep,2015,12(1):23-34 heart diseases:emerging role in diabetic cardiomyopathy
[66] KWONG J Q,LU X,CORRELL R N,et al. The mitochon⁃ [J]. J Mol Cell Cardiol,2019,127:246-259
drial calcium uniporter selectively matches metabolic out⁃ [79] DESPA S. Myocyte[Na(+)] i dysregulation in heart fail⁃
put to acute contractile stress in the heart[J]. Cell Rep, ure and diabetic cardiomyopathy[J]. Front Physiol,2018,
2015,12(1):15-22 9:1303
[67] PAN X,LIU J,NGUYEN T,et al. The physiological role [80] ZHENG H,ZHU H,LIU X,et al. Mitophagy in diabetic