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第42卷第9期              周   滢,娄宇轩,孙 伟,等. 线粒体离子通道在心血管疾病中的研究进展[J].
                  2022年9月                    南京医科大学学报(自然科学版),2022,42(09):1322-1334                      ·1333 ·


                    registry for pulmonary arterial hypertension:1982 ⁃ 2006  [144]ALTSCHAFL B A,BEUTNER G,SHARMA V K,et al.
                    [J]. Eur Respir J,2007,30(6):1103-1110             The mitochondrial ryanodine receptor in rat heart:a phar⁃
               [132]SNOW J B,NORTON C E,SANDS M A,et al. Intermit⁃     maco ⁃ kinetic profile[J]. Biochim Biophys Acta,2007,
                    tent hypoxia augments pulmonary vasoconstrictor reactivity  1768(7):1784-1795
                    through PKCbeta/mitochondrial oxidant signaling[J]. Am  [145]GRIFFITHS E J,HALESTRAP A P. Protection by cyclo⁃
                    J Respir Cell Mol Biol,2020,62(6):732-746          sporin A of ischemia/reperfusion⁃induced damage in iso⁃
               [133]HU H L,ZHANG Z X,CHEN C S,et al. Effects of mito⁃  lated rat hearts[J]. J Mol Cell Cardiol,1993,25(12):
                    chondrial potassium channel and membrane potential on  1461-1469
                    hypoxic human pulmonary artery smooth muscle cells[J].  [146]DUCHEN M R,MCGUINNESS O,BROWN L A,et al. On
                    Am J Respir Cell Mol Biol,2010,42(6):661-666       the involvement of a cyclosporin A sensitive mitochondrial
               [134]JURASZ P,COURTMAN D,BABAIE S,et al. Role of        pore in myocardial reperfusion injury[J]. Cardiovasc Res,
                    apoptosis in pulmonary hypertension:from experimental  1993,27(10):1790-1794
                    models to clinical trials[J]. Pharmacol Ther,2010,126  [147]WEINBRENNER C,LIU G S,DOWNEY J M,et al. Cy⁃
                    (1):1-8                                            closporine A limits myocardial infarct size even when ad⁃
               [135]WANG H,ZUO X,WANG Q,et al. Nicorandil inhibits hy⁃  ministered after onset of ischemia[J]. Cardiovasc Res,
                    poxia⁃induced apoptosis in human pulmonary artery endo⁃  1998,38(3):676-684
                    thelial cells through activation of mitoKATP and regula⁃  [148]SKYSCHALLY A,SCHULZ R,HEUSCH G. Cyclosporine
                    tion of eNOS and the NF⁃kappaB pathway[J]. Int J Mol  A at reperfusion reduces infarct size in pigs[J]. Cardio⁃
                    Med,2013,32(1):187-194                             vasc Drugs Ther,2010,24(1):85-87
               [136]ZHANG Y Q,TIAN F,ZHOU Y,et al. Nicorandil attenu⁃  [149]WALDMEIER P C,FELDTRAUER J J,QIAN T,et al. In⁃
                    ates carotid intimal hyperplasia after balloon catheter injury  hibition of the mitochondrial permeability transition by
                    in diabetic rats[J]. Cardiovasc Diabetol,2016,15:62  the nonimmunosuppressive cyclosporin derivative NIM811
               [137]DONG L,LI Y,HU H,et al. Potential therapeutic targets  [J]. Mol Pharmacol,2002,62(1):22-29
                    for hypoxia⁃induced pulmonary artery hypertension[J]. J  [150]GROVER G J,GARLID K D. ATP ⁃ sensitive potassium
                    Transl Med,2014,12:39                              channels:a review of their cardioprotective pharmacology
               [138]HONG Z,CHEN K H,DASGUPTA A,et al. MicroRNA⁃       [J]. J Mol Cell Cardiol,2000,32(4):677-695
                    138 and microRNA⁃25 down⁃regulate mitochondrial calci⁃  [151]GARLID K D,PAUCEK P,YAROV⁃YAROVOY V,et al.
                    um uniporter,causing the pulmonary arterial hypertension  Cardioprotective effect of diazoxide and its interaction
                    cancer phenotype[J]. Am J Respir Crit Care Med,2017,  with mitochondrial ATP ⁃ sensitive K channels. possible
                                                                                                  +
                    195(4):515-529                                     mechanism of cardioprotection[J]. Circ Res,1997,81
               [139]BAUGHMAN J M,PEROCCHI F,GIRGIS H S,et al. In⁃     (6):1072-1082
                    tegrative genomics identifies MCU as an essential compo⁃  [152]GROVER G J,D’ALONZO A J,GARLID K D,et al.
                    nent of the mitochondrial calcium uniporter[J]. Nature,  Pharmacologic characterization of BMS⁃ 191095,a mito⁃
                    2011,476(7360):341-345                             chondrial K(ATP)opener with no peripheral vasodilator
               [140]WOODS J J,NEMANI N,SHANMUGHAPRIYA S,et al.         or cardiac action potential shortening activity[J]. J Phar⁃
                    A Selective and cell ⁃ permeable mitochondrial calcium  macol Exp Ther,2001,297(3):1184-1192
                    uniporter(MCU)inhibitor preserves mitochondrial bioener  [153]LEE S,YI K Y,KIM S K,et al. Cardioselective anti⁃ische⁃
                    ⁃ getics after hypoxia/reoxygenation injury[J]. ACS Cent  mic ATP ⁃ sensitive potassium channel(KATP)openers:
                    Sci,2019,5(1):153-166                              benzopyranyl indoline and indole analogues[J]. Eur J
               [141]KON N,MURAKOSHI M,ISOBE A,et al. DS16570511        Med Chem,2003,38(5):459-471
                    is a small⁃molecule inhibitor of the mitochondrial calcium  [154]DAS B,SARKAR C. Is the sarcolemmal or mitochondrial
                    uniporter[J]. Cell Death Discov,2017,3:17045       K(ATP)channel activation important in the antiarrhyth⁃
               [142]ARDUINO D M,WETTMARSHAUSEN J,VAIS H,et al.         mic and cardioprotective effects during acute ischemia/re⁃
                    Systematic identification of mcu modulators by orthogonal  perfusion in the intact anesthetized rabbit model?[J].
                    interspecies chemical screening[J]. Mol Cell,2017,67  Life Sci,2005,77(11):1226-1248
                    (4):711-723 e717                             [155]GROSS G J,AUCHAMPACH J A. Blockade of ATP⁃sen⁃
               [143]DI MARCO G,VALLESE F,JOURDE B,et al. A High⁃       sitive potassium channels prevents myocardial precondi⁃
                    throughput screening identifies MICU1 targeting com⁃  tioning in dogs[J]. Circ Res,1992,70(2):223-233
                    pounds[J]. Cell Rep,2020,30(7):2321-2331     [156]SATO T,SASAKI N,O’ROURKE B,et al. Nicorandil,a
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