Page 93 - 南京医科大学学报自然科学版
P. 93
第42卷第9期 南京医科大学学报(自然科学版)
2022年9月 Journal of Nanjing Medical University(Natural Sciences) ·1287 ·
·临床研究·
6 096例健康体检教师人群甲状腺结节检出率及影响因素分析
季 明 ,张 楷 ,邹子鸣 ,郭 玲 3
1,2
1*
1,2
南京医科大学附属逸夫医院健康管理中心,江苏 南京 211100;南京医科大学康达学院临床医学系,江苏 连云港
1 2
222000;南京医科大学附属逸夫医院信息网络部,江苏 南京 211100
3
[摘 要] 目的:了解健康体检教师人群中甲状腺结节(thyroid nodule,TN)的检出率及影响因素。方法:回顾分析2018年10月
—2021年6月在南京医科大学附属逸夫医院健康教师体检人群检查项目(包括性别、年龄、职业、身高、体重等),实验室检查
13
(空腹血糖、血脂、肝功能、尿酸、C呼气检测等)及甲状腺彩超检查。应用Logistic 多因素回归分析TN的影响因素。结果:①
纳入研究的6 096例体检者中,检查发现TN 2 539例,总检出率为41.65%,其中男性TN检出率38.20%,女性TN检出率43.03%;
单发结节检出率 1 340 例(21.98%),多发结节检出率 1 199 例(19.67%);对于 TN 根据 TI⁃RADS 分级,结果表明 3 级最多,占
22.74%;年龄越大检出率越高,各年龄组之间 TN 检出率差异有统计学意义(P < 0.05);此外 TN 检出部位分别是双侧叶
(17.27%)>右侧叶(13.27%)>左侧叶(10.89%)>甲状腺峡部(0.21%);②女性教师人群以中教组检出率最高(49.44%),其中<
30岁、30~39岁和≥60岁3组内不同教师类型检出率差异有统计学意义(P < 0.05);③和非TN组相比,TN组高血压、空腹血糖
异常,高脂血症、超重肥胖发生率较高,两组差异有统计学意义(P < 0.05);④经Logistic多因素回归分析显示,女性是TN发病
的独立危险因素(OR=1.913,P < 0.05),与<30 岁相比,40~49 岁、50~59 岁、≥60 岁教师的 TN 发病风险较高(OR=1.402、2.923、
4.637,均P < 0.05),而与幼教组相比,高校教师的TN发病风险较低(OR=0.718,P < 0.05)。结论:健康体检的教师人群中TN的
检出率虽然偏高,但恶性度不高,超重肥胖、“三高”和TN密切相关,女性、年龄、中学教师是TN的危险因素,需综合关注上述指
标,提高健康管理意识。
[关键词] 教师人群;甲状腺结节;检出率;影响因素
[中图分类号] R581.3 [文献标志码] A [文章编号] 1007⁃4368(2022)09⁃1287⁃07
doi:10.7655/NYDXBNS20220914
Detection rate of thyroid nodules and analysis of influencing factors in 6 096 cases of
teacher population in healthy examination
1* 1,2 1,2 3
JI Ming ,ZHANG Kai ,ZOU Ziming ,GUO Ling
1 Health Management Center,Sir Run Run Hospital Affiliated to Nanjing Medical University,Nanjing 211100;
3
2 Department of Clinical Medicine,Kangda College,Nanjing Medical University,Lianyungang 222000;Information
Network Department,Sir Run Run Hospital Affiliated to Nanjing Medical University,Nanjing 211100,China
[Abstract] Objective: This study aims to investigate the detection rate and influencing factors of thyroid nodules(TN)among
healthy teachers. Methods:The physical examination items(including gender,age,occupation,height,weight,etc.),laboratory
13
examination(fasting blood glucose,blood lipid,liver function,uric acid,C breath test,etc.)and thyroid color ultrasound examination
of health teachers in Sir Run Run Hospital Affiliated to Nanjing Medical University from October 2018 to June 2021 were
retrospectively analyzed. Logistic regression was used to analyze the influencing factors of TN. Results:①Thyroid nodules were found
in 2 539 of 6 096 patients,with a total detection rate of 41.65%,including 38.20% male and 43.03% female. There were 1 340 single
nodules(21.98%)and 1 199 multiple nodules(19.67%). For TN classification according to TI⁃RADS,grade 3 was the most,accounting
for 22.74%. The older the age,the higher the detection rate was,and there were significant differences in the detection rate of TN
among different age groups(P < 0.05). In addition,thyroid nodules were detected in bilateral lobe(17.27%)> right lobe(13.27%)> left
lobe(10.89%)> thyroid isthmus(0.21%). ② The detection rate of female teachers in the middle school group was the highest
[基金项目] 江苏省卫健委指导性课题(Z2018042);南京医科大学重点项目专项基金(2017NJMUZD131)
∗
通信作者(Corresponding author),E⁃mail: 490853342@qq.com