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南京医科大学学报(自然科学版) 第44卷第8期
·1146 · Journal of Nanjing Medical University(Natural Sciences) 2024年8月
·流行病学研究·
江苏省2004—2022年传染病突发公共卫生事件趋势分析
陈紫颖 ,刘 鑫 ,刘文东 ,沈文琪 ,吴 莹 ,时影影 2,3* ,胡建利 1,2,3,4*
1
2,3
2,3
2,3
1
南京医科大学公共卫生学院,江苏 南京 211166;江苏省疾病预防控制中心急性传染病防制所,国家卫生健康委员会肠道病
1 2 3
4
原微生物重点实验室,江苏省卫生应急工程研究中心,江苏 南京 210009
[摘 要] 目的:分析江苏省传染病突发公共卫生事件的流行特征,为防控工作开展提供科学依据。方法:采用joinpoint回归
模型分析时间维度变化趋势,采用时空重排扫描探测时空聚集性。结果:2004—2022年累计报告传染病突发事件3 641起,累
计报告发病 131 880 例,死亡 73 例,涉及 25 种法定传染病突发事件 1 868 起,其中甲类 76 起、乙类 391 起、丙类 1 401 起;涉及
8 种其他传染病突发事件 1 773 起。Joinpoint 回归分析显示全省事件数呈增加趋势[平均年度变化百分比(average APC,
AAPC)=16.28,P < 0.05)],甲类自2006年呈下降趋势(AAPC=-18.23,P < 0.05),乙类、丙类、其他均呈增加趋势(AAPC>0,P <
0.05),苏南、苏中、苏北各区域事件数全局均呈增加趋势(AAPC>0,P < 0.05),苏南分为“快速增加—慢速增加—快速增加—减
少”4个阶段,苏中事件数单调增加,苏北分为“增加—慢速减少—快速增加—减少”4个阶段。2006年、2015年、2018年为主要
转折点。时空重排扫描共探测出8个时空聚集区,按发生顺序分别分布在苏中+苏南—苏北—苏南—苏南+苏北。结论:江苏
省传染病突发事件总体呈现增加趋势,苏南和苏北聚集,苏中相对分散,重点地区需做好水痘、流行性感冒、手足口病等重点传
染病的疫情监测和防控。
[关键词] 传染病;突发公共卫生事件;joinpoint回归模型;时空重排扫描;趋势分析
[中图分类号] R181.2 [文献标志码] A [文章编号] 1007⁃4368(2024)08⁃1146⁃09
doi:10.7655/NYDXBNSN231105
Analysis of the trend of public health emergencies of infectious diseases in Jiangsu
Province from 2004 to 2022
1 1 2,3 2,3 2,3 2,3* 1,2,3,4*
CHEN Ziying ,LIU Xin ,LIU Wendong ,SHEN Wenqi ,WU Ying ,SHI Yingying ,HU Jianli
1 School of Public Health,Nanjing Medical University,Nanjing 211166;Acute Infectious Disease Prevention and
2
4
Control Institute,National Health Commission(NHC)Key Laboratory of Enteric Pathogenic Microbiology,Jiangsu
3
Provincial Health Emergency Engineering Research Center,Jiangsu Provincial Center for Disease Control and
Prevention,Nanjing 210009,China
[Abstract] Objective:To analyze the epidemic characteristics of public health emergencies of infectious disease in Jiangsu
Province,and to provide scientific basis for prevention and control efforts. Methods:Joinpoint regression model was used to analyze the
temporal trends,and space⁃time permutation scan was employed for spatiotemporal cluster detection and exploration. Results:From
2004 to 2022,a total of 3 641 emergencies were reported,with 131 880 cases and 73 deaths. There were 1 868 emergencies involving
25 notifiable infectious diseases,including 76 Class A,391 Class B,and 1 401 Class C diseases. Additionally,1 773 emergencies of 8
other non⁃notifiable infectious diseases were involved. Joinpoint regression analysis revealed that the number of emergencies in Jiangsu
Province showed an increasing trend[average APC(AAPC)=16.28,P < 0.05)]. Class A showed a declining trend since 2006
(AAPC =-18.23,P < 0.05),while Class B,Class C,and others exhibited increasing trends(AAPC>0,P < 0.05). Emergencies in
Southern of Jiangsu,Middle of jiangsu,and Northern of Jiangsu all showed increasing trend(AAPC>0,P < 0.05). In Southern of
Jiangsu,the trend was characterized by 4 stages:rapid increase,slow increase,rapid increase,and decrease. In Middle of Jiangsu,
Emergencies showed a monotonic increase. In Northern of Jiangsu,the trend was characterized by 4 stages:increase,slow decrease,
[基金项目] 十四五江苏省科教能力提升工程—江苏省流行病学重点学科(ZDXK202250);2023年江苏省卫健委定向委托研
究重点项目—“新冠高强度流行后再感染风险和影响因素研究”(DX202302)
∗
通信作者(Corresponding author),E⁃mail:episyy@163.com;jshjl@jscdc.cn

