Page 57 - 南京医科大学自然版
P. 57
第44卷第9期 郭 琼,唐娜娜,焦春花,等. 气囊辅助式小肠镜在诊断Meckel憩室中的应用价值[J].
2024年9月 南京医科大学学报(自然科学版),2024,44(9):1227-1231 ·1229 ·
表1 Meckel憩室合并并发症分析
Table 1 Analysis of complications associated with Meckel’s diverticulum
With complications
Without
Clinical data Gastrointestinal Intestinal P c
a b
Diverticulitis Total P complications
bleeding obstruction
Numbers[n(%)] .30(54.5) 14(25.5)0 11(20)0.0. 55 - 32 -
Sex(male/female,n) 24/6 9/5 8/3 41/14 0.545 20/12 0.273
Age[years,M(P25,P75)] 26.5(17.8,41) 38(17,67.3) 38(19,64). 29(18,52) 0.288 49.5(29.3,63) 0.003
Disease duration[d,M(P25,P75)] 0.07(3,155.8) 04(2,8)0.0 007(1,158.8) 7(2,60) 0.339 - -
Distance to ileocecal valve(cm,x ± s) 76.9 ± 25.2 62.5 ± 19.7 62.2 ± 31.5 70.2 ± 25.6 0.138 74.3 ± 28.8 0.479
MD length(cm,x ± s) 5.6 ± 2.5 5.6 ± 3.0 3.4 ± 1.5 5.2 ± 2.6 0.070 3.3 ± 1.4 0.001
MD width(cm,x ± s) 2.3 ± 1.0 2.6 ± 1.4 2.4 ± 0.9 2.4 ± 1.1 0.819 1.6 ± 0.7 0.002
Surgical rate[n(%)] .25(83.3) 14(100.0) 10(90.9)0 49(89.1) 0.316 0.18(56.3) <0.001
Preoperative diagnosis rate[n(%)] .19(76.0) 1(7.1)0 1(10.0) 21(42.9) 0.000 d 0(0) 0.001
Ectopic tissues on pathology[n(%)] .11(42.3) 2(14.3) 0(0)0.0 13(26.0) 0.019 e 0.02(13.3) 0.488
Gastric tissue[n(%)] .11(42.3) 0(0)0.0 0(0)0.0 11(22.0) 0.001 f 0(0) 0.055
Pancreatic tissue[n(%)] 0(0)0 2(14.3) 0(0)0.0 2(4.0) 0.111 0.02(13.3) 0.226
a:Diverticulitis(combined gastrointestinal perforation or not);b:P⁃value comparing intestinal obstruction,gastrointestinal bleeding,and diverticu⁃
litis;c:P⁃value comparing the groups with and without complications;d:The gastrointestinal bleeding and intestinal obstruction groups differed from
one another after multiple comparisons using Bonferroni’s method(P < 0.05);e:The gastrointestinal bleeding and diverticulitis groups differed from
one another after multiple comparisons using Bonferroni’s method(P < 0.05);f:There was a difference between the groups with gastrointestinal bleed⁃
ing and intestinal obstruction(P < 0.05)and gastrointestinal bleeding and diverticulitis(P < 0.05)after multiple comparisons using the Bonferroni’s
method.
2.3 不同检查方法对Meckel憩室的诊断价值 由此可见,气囊辅助式小肠镜对Meckel憩室的
研究评估了6种不同的检查方法对小肠Meckel 诊断灵敏度最高,仅有 2 例因进镜困难未能顺利达
憩室的诊断价值,计算各种方法的诊断灵敏度。结 到憩室位置而漏诊。此外,15例患者在小肠镜检查
果如下:腹部 CT 8.2%(4/49);小肠 CT 9.4%(3/32); 中发现憩室旁或憩室内溃疡,1 例见异位胃黏膜样
数字减影血管造影 0(0/9);核素显像 58.3%(7/12); 结构,1 例见黏膜桥,1 例见活动性出血并行内镜下
胶囊内镜 30.0%(3/10);气囊辅助式小肠镜 94.4% 钛夹止血治疗。
(34/36,表2)。 2.4 临床结局
此外,腹部 CT 有 4 例提示不明原因的肠壁增 有67例Meckel憩室患者接受手术治疗,腹腔镜
厚、1例肠腔内占位,诊断获益率为18.4%(9/49);小 手术16例,开腹手术51例,包括急诊开腹探查21例,
肠CT 发现2例肠壁增厚、1例肠腔狭窄、4例腔内占 术前仅21例明确诊断Meckel憩室。另外20例未手
位以及 1 例肠套叠梗阻,诊断获益率为 34.4%(11/ 术患者中,14例为偶然发现的无并发症的Meckel憩
32);胶囊内镜 2 例发现回肠溃疡、1 例腔内占位,诊 室患者,5例合并消化道出血,1例合并憩室炎,经保
断获益率为60.0%(6/10)。 守治疗后好转。对手术切除的 Meckel 憩室标本进
表2 不同检查方法对Meckel’s憩室诊断的价值
Table 2 The diagnostic value of different examination methods for Meckel’s diverticulum
Total Certain Meckel’s Other significant Diagnostic sensitivity Diagnostic yield
Different methods
(n) diverticulum findings [%(95%CI)] [%(95%CI)]
Abdominal CT 49 04 5 8.2(2.3-19.6) 18.4(8.8-32.0)0
CT enterography 32 03 8 9.4(2.0-25.0) 34.4(18.6-53.2)
Digital subtraction angiography 09 00 0 .0(0-33.6 ) 0(0-33.6)
Nuclide imaging 12 07 0 58.3(27.7-84.8) 58.3(27.7-84.8)
Capsule endoscopy 10 03 3 30.0(6.7-65.2)0 60.0(26.2-87.8)
Balloon⁃assisted small enteroscopy 36 34 0 94.4(81.3-99.3) 94.4(81.3-99.3)

