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第45卷第1期           肖   宁,肖锦华,黄 海,等. COVID⁃19对前列腺增生患者逼尿肌收缩功能的影响[J].
                  2025年1月                      南京医科大学学报(自然科学版),2025,45(1):22-28                         · 27  ·


                功能的“head⁃to⁃head”研究 。                                 COVID⁃19[J]. New Eng J Med,2020,383(25):2451-60.
                                       [22]
                    本研究存在一定的局限性。首先,本研究虽然                         [4] TRISTÃO L S,BRESLER R,MODESTO V A,et al.
                纳入不同地区 2 个单位的病例,但是纳入样本数量                               Urological complications of COVID ⁃ 19 :a systematic
                仍较少,尚需开展大样本、多中心研究,研究结论供                                review[J]. Int Braz J Urol,2023,49(1):24-40
                                                                 [5] MARAND A J B,JANSSEN D,HEESAKKERS J,et al.
                临床参考。另外,本研究为回顾性研究,而且选择
                                                                       Lower urinary tract signs and symptoms in patients with
                的 BPH 患者年龄较大,普遍存在 BOO,可能已有潜
                                                                       COVID⁃19[J]. BMC Infect Dis,2021,21(1):706
                在的DU,存在样本选择偏倚风险。最后,本研究缺                          [6] 唐蓉玉,肖      宁,赵划晟,等. 女性膀胱出口梗阻的超声
                乏逼尿肌功能正常人群的对比研究,而且不能排除                                 影像尿动力学检查特点分析[J]. 中华泌尿外科杂志,
                COVID(-)组存在隐性感染可能,亟待日后更广泛                              2021,42(5):385-387
                人群的前瞻性研究取得更确实的结论。                                      Tang R Y,XIAO N,ZHAO H S. et al. Analysis of sonogra⁃
                    综上所述,结合 COVID⁃19 导致长期多器官功                          phy video urodynamics studies in characteristics of pa⁃
                能障碍的可能,“long⁃COVID”的诊治受到广泛重                            tients with female bladder outlet obstruction[J]. Chinese
                                                                       Journal of Urology,2021,42(5):385-387
                视 [23-25] 。笔者认为,BPH患者若合并COVID⁃19可能
                                                                 [7] ROSIER P F W M,SCHAEFER W,LOSE G,et al. Inter⁃
                进一步加重 DU,导致 PVR 增加甚至尿潴留,DU 可
                                                                       national continence society good urodynamics practices
                能是老年 BPH/BOO 患者“long⁃COVID”UDS 表现之                     and terms 2016:urodynamics,uroflowmetry,cystometry,
                一。因此,BPH 患者若合并 COVID⁃19,需警惕逼尿                          and pressure⁃flow study[J]. Neurourol Urodyn,2017,36
                肌收缩功能受损风险,及时评估 PVR 等指标,早期                             (5):1243-1260
                处理并发症及保护膀胱功能。                                    [8] 郭广荣. 不同体积前列腺的膀胱出口梗阻手术患者超
                   利益冲突声明:                                             声影像尿动力学研究[D]. 桂林:桂林医学院,2023
                   所有作者声明无利益冲突。                                        GUO G R. The research of sonography video urodynamics
                   Conflict of Interests:                              studies on patients with different prostate volume under⁃
                                                                       went surgery for bladder outlet obstruction[D]. Guilin:
                   The author reports no conflicts of interests in this work.
                   作者贡献声明:                                             Guilin Medical University,2023
                   肖宁、肖锦华、黄海、唐琦、赵划晟和王建峰设计研究方                     [9] GUO Y R,CAO Q D,HONG Z S,et al. The origin,trans⁃
                案;肖宁、肖锦华、唐琦、陈丹、黄秋夏、赵划晟和王建峰实施                           mission and clinical therapies on coronavirus disease
                研究方案;肖宁、肖锦华和唐琦分析数据;肖宁和肖锦华撰写                            2019(COVID⁃19)outbreak ⁃ an update on the status[J].
                和修改论文。                                                 Mil Med Res,2020,7(1):11
                   Author’s Contributions:                       [10]SINGH S J,BALDWIN M M,DAYNES E,et al. Respira⁃
                   XIAO Ning,XIAO Jinhua,HUANG Hai,TANG Qi,ZHAO        tory sequelae of COVID⁃19:pulmonary and extrapulmo⁃
                                                                       nary origins,and approaches to clinical care and rehabili⁃
                Huashen,and WANG Jianfeng designed the research;XIAO
                Ning,XIAO Jinhua,TANG Qi,CHEN Dan,HUANG Qiuxia,        tation[J]. Lancet Respir Med,2023,11(8):709-725
                ZHAO Huashen,and WANG Jianfeng performed research;  [11]DHAWAN A,GANDUBOINA R,DUTTA P,et al. COVID
                                                                       ⁃ associated cystitis:the culprit behind the bladder woes
                XIAO Ning,XIAO Jinhua,and TANG Qi analyzed data;XIAO
                                                                       post ⁃ COVID infection? A review[J]. Int Urol Nephrol,
                Ning and XIAO Jinhua wrote and revised the manuscript.
                                                                       2023,55(10):2367-2372
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