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第45卷第6期          何玉立,刘倩慧,王 瀚,等. 衰弱与老年房颤患者导管消融术后复发的相关性研究[J].
                  2025年6月                     南京医科大学学报(自然科学版),2025,45(6):854-862                        ·857 ·


                                                    表1   3组患者基线资料的比较
                                    Table 1 Comparison of baseline data among the three groups of patients
                          Characteristic       Non⁃frail group(n=94) Pre⁃frail group(n=138)  Frail group(n=60)  Statistic  P
                Age[years,M(P25,P75)]          067.50(65.00,69.75) 070.00(67.00,73.00) 072.00(69.00,76.00)  35.710 <0.001
                                                                                                 a
                                                                               a
                Male[n(%)]                     0.0058(61.70)    0.0073(52.90)     000.27(45.00)      04.269 0.118
                BMI(kg/m ,x ± s)               24.51 ± 2.3340000000 24.18 ± 3.4200000000 25.11 ± 3.760000000000 01.771 0.172
                       2
                Smoking[n(%)]                  0.0027(28.72)    000.24(17.39)     000.11(18.33)      04.673 0.097
                Drinking[n(%)]                 0.0025(26.60)    000.22(15.94)     000.13(21.67)      03.945 0.139
                The type of AF[n(%)]                                                                 06.886 0.032
                                                                                            a
                  ParoxysmalAF                 0.0058(61.70)    000.82(59.42)     000.25(41.67)
                                                                                            a
                  Persistent AF                0.0036(38.30)    000.56(40.58)     000.35(58.33)
                AF duration[months,M(P25,P75)]  008.00(3.00,24.00)  012.00(3.00,36.00)  012.00(4.75,36.00)  03.005 0.223
                AF recurrence[n(%)]            0.0010(10.64)    000.19(13.77)     000.23(38.33)      22.110 <0.001
                                                                                            ab
                Comorbidities[n(%)]
                  Hypertension                 0.0055(58.51)    000.96(69.57)     000.42(70.00)      03.563 0.168
                                                                          a
                  Diabetes                     0.0009(9.57)     000.33(23.91)     000.14(23.33)      08.258 0.016
                  Coronary heart disease       0.0021(22.34)    000.36(26.09)     000.16(26.67)      00.530 0.767
                  Stroke                       0.0014(14.89)    000.37(26.81)     000.17(28.33)      05.522 0.063
                Serum biomarkers[M(P25,P75)]
                  FPG(mmol/L)                  004.63(4.33,5.17)  004.80(4.19,5.37)  004.87(4.29,5.53)  01.335 0.513
                  HbA1c(%)                     005.67(5.47,5.97)  005.83(5.55,6.36)  005.93(5.61,6.37)  06.683 0.035
                  Scr(μmol/L)                  074.65(64.93,84.63) 074.80(65.95,83.98) 070.15(61.23,88.43)  00.398 0.819
                  UA(μmol/L)                   344.00(300.25,396.50)317.00(271.50,395.00)345.50(293.50,421.50)  04.072 0.131
                  TC(mmol/L)                   004.11(3.39,4.80)  003.72(3.04,4.37)  003.54(3.07,4.32)  09.155 0.010
                                                                                               a
                                                                             a
                  TG(mmol/L)                   001.21(0.98,1.76)  001.17(0.85,1.53)  001.13(0.92,1.67)  03.637 0.162
                  HDL⁃C(mmol/L)                001.15(1.01,1.29)  001.10(0.97,1.25)  001.04(0.89,1.25)  06.529 0.038
                                                                                               a
                  LDL⁃C(mmol/L)                002.57(1.91,3.05)  002.26(1.76,2.80)  002.19(1.79,2.80)  05.755 0.056
                  NT⁃proBNP(ng/L)              211.00(110.20,528.20)354.45(111.18,821.20)711.40(284.23,1 315.50) 26.186 <0.001
                                                                                                    ab
                                                                                 a
                  hs⁃cTnT(ng/L)                008.99(7.00,12.13)  009.34(7.73,12.61)  011.07(8.72,15.84) ab  10.430 0.005
                  ALB(g/L)                     039.30(37.38,41.08) 038.70(36.80,40.68) 037.75(35.45,40.00)  11.108 0.004
                                                                                                 a
                Echocardiographic parameters[M(P25,P75)]
                  LAD(mm)                      041.00(38.00,43.00) 041.00(38.00,44.00) 043.00(41.00,45.00)  14.547 <0.001
                                                                                                 ab
                  LVDd(mm)                     048.00(46.00,50.00) 047.50(45.00,50.00) 048.00(45.00,50.00)  01.773 0.412
                  LVDs(mm)                     031.00(30.00,33.00) 031.00(30.00,34.00) 032.00(30.00,33.00)  00.655 0.721
                  LVEF(%)                      063.00(60.90,64.70) 062.25(60.90,63.70) 062.70(60.98,64.00)  00.954 0.621
                Medication history[n(%)]
                  ACEI                         00.000(0)        000.05(3.62)      000.00(0)            -    0.085
                  ARB                          0.0036(38.30)    000.55(39.86)     000.25(41.67)      00.175 0.916
                  Beta⁃block                   0.0029(30.85)    000.55(39.86)     000.22(36.67)      01.965 0.374
                  CCB                          0.0027(28.72)    000.51(36.96)     000.16(26.67)      02.792 0.248
                  Statins                      0.0051(54.26)    000.84(60.87)     000.37(61.67)      01.249 0.536
                  Antiplatelet drugs           0.0007(7.45)     000.12(8.70)      000.07(11.67)      00.818 0.664
                                                                          a
                  Antihyperglycemic drugs      0.0010(10.64)    000.32(23.19)     000.13(21.67)      06.157 0.046
                  Anticoagulant drugs          0.0090(95.74)    00.137(99.28)     000.59(98.33)        -    0.157
                  Antiarrhythmic drugs         0.0081(86.17)    00.119(86.23)     000.54(90.00)      00.606 0.739
                   a:indicates that compared with the patients in the non⁃frail group,the difference is statistically significant(P < 0.05);b:indicates that compared
                with the patients in the pre⁃frail group,the difference is statistically significant(P < 0.05). AF:atrial fibrillation;BMI:body mass index;FPG:fasting
                plasma glucose;HbA1c:hemoglobin A1c;Scr:serum creatinine;UA:uric acid;TC:total cholesterol;TG:triglyceride;HDL⁃C:high⁃density lipoprotein
                cholesterol;LDL⁃C:low⁃density lipoprotein cholesterol;NT⁃proBNP:N⁃terminal pro⁃B⁃type natriuretic peptide;hs⁃cTnT:high⁃sensitivity cardiac tropo⁃
                nin T;ALB:albumin;LAD:left atrial diameter;LVDd:left ventricular diastolic dimension;LVDs:left ventricular systolic dimension;LVEF:left ventric⁃
                ular ejection fraction;ACEI:angiotensin⁃converting enzyme inhibitor;ARB:angiotensin Ⅱ receptor blockers;CCB:calcium channel blocker.
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