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第45卷第6期 何玉立,刘倩慧,王 瀚,等. 衰弱与老年房颤患者导管消融术后复发的相关性研究[J].
2025年6月 南京医科大学学报(自然科学版),2025,45(6):854-862 ·857 ·
表1 3组患者基线资料的比较
Table 1 Comparison of baseline data among the three groups of patients
Characteristic Non⁃frail group(n=94) Pre⁃frail group(n=138) Frail group(n=60) Statistic P
Age[years,M(P25,P75)] 067.50(65.00,69.75) 070.00(67.00,73.00) 072.00(69.00,76.00) 35.710 <0.001
a
a
Male[n(%)] 0.0058(61.70) 0.0073(52.90) 000.27(45.00) 04.269 0.118
BMI(kg/m ,x ± s) 24.51 ± 2.3340000000 24.18 ± 3.4200000000 25.11 ± 3.760000000000 01.771 0.172
2
Smoking[n(%)] 0.0027(28.72) 000.24(17.39) 000.11(18.33) 04.673 0.097
Drinking[n(%)] 0.0025(26.60) 000.22(15.94) 000.13(21.67) 03.945 0.139
The type of AF[n(%)] 06.886 0.032
a
ParoxysmalAF 0.0058(61.70) 000.82(59.42) 000.25(41.67)
a
Persistent AF 0.0036(38.30) 000.56(40.58) 000.35(58.33)
AF duration[months,M(P25,P75)] 008.00(3.00,24.00) 012.00(3.00,36.00) 012.00(4.75,36.00) 03.005 0.223
AF recurrence[n(%)] 0.0010(10.64) 000.19(13.77) 000.23(38.33) 22.110 <0.001
ab
Comorbidities[n(%)]
Hypertension 0.0055(58.51) 000.96(69.57) 000.42(70.00) 03.563 0.168
a
Diabetes 0.0009(9.57) 000.33(23.91) 000.14(23.33) 08.258 0.016
Coronary heart disease 0.0021(22.34) 000.36(26.09) 000.16(26.67) 00.530 0.767
Stroke 0.0014(14.89) 000.37(26.81) 000.17(28.33) 05.522 0.063
Serum biomarkers[M(P25,P75)]
FPG(mmol/L) 004.63(4.33,5.17) 004.80(4.19,5.37) 004.87(4.29,5.53) 01.335 0.513
HbA1c(%) 005.67(5.47,5.97) 005.83(5.55,6.36) 005.93(5.61,6.37) 06.683 0.035
Scr(μmol/L) 074.65(64.93,84.63) 074.80(65.95,83.98) 070.15(61.23,88.43) 00.398 0.819
UA(μmol/L) 344.00(300.25,396.50)317.00(271.50,395.00)345.50(293.50,421.50) 04.072 0.131
TC(mmol/L) 004.11(3.39,4.80) 003.72(3.04,4.37) 003.54(3.07,4.32) 09.155 0.010
a
a
TG(mmol/L) 001.21(0.98,1.76) 001.17(0.85,1.53) 001.13(0.92,1.67) 03.637 0.162
HDL⁃C(mmol/L) 001.15(1.01,1.29) 001.10(0.97,1.25) 001.04(0.89,1.25) 06.529 0.038
a
LDL⁃C(mmol/L) 002.57(1.91,3.05) 002.26(1.76,2.80) 002.19(1.79,2.80) 05.755 0.056
NT⁃proBNP(ng/L) 211.00(110.20,528.20)354.45(111.18,821.20)711.40(284.23,1 315.50) 26.186 <0.001
ab
a
hs⁃cTnT(ng/L) 008.99(7.00,12.13) 009.34(7.73,12.61) 011.07(8.72,15.84) ab 10.430 0.005
ALB(g/L) 039.30(37.38,41.08) 038.70(36.80,40.68) 037.75(35.45,40.00) 11.108 0.004
a
Echocardiographic parameters[M(P25,P75)]
LAD(mm) 041.00(38.00,43.00) 041.00(38.00,44.00) 043.00(41.00,45.00) 14.547 <0.001
ab
LVDd(mm) 048.00(46.00,50.00) 047.50(45.00,50.00) 048.00(45.00,50.00) 01.773 0.412
LVDs(mm) 031.00(30.00,33.00) 031.00(30.00,34.00) 032.00(30.00,33.00) 00.655 0.721
LVEF(%) 063.00(60.90,64.70) 062.25(60.90,63.70) 062.70(60.98,64.00) 00.954 0.621
Medication history[n(%)]
ACEI 00.000(0) 000.05(3.62) 000.00(0) - 0.085
ARB 0.0036(38.30) 000.55(39.86) 000.25(41.67) 00.175 0.916
Beta⁃block 0.0029(30.85) 000.55(39.86) 000.22(36.67) 01.965 0.374
CCB 0.0027(28.72) 000.51(36.96) 000.16(26.67) 02.792 0.248
Statins 0.0051(54.26) 000.84(60.87) 000.37(61.67) 01.249 0.536
Antiplatelet drugs 0.0007(7.45) 000.12(8.70) 000.07(11.67) 00.818 0.664
a
Antihyperglycemic drugs 0.0010(10.64) 000.32(23.19) 000.13(21.67) 06.157 0.046
Anticoagulant drugs 0.0090(95.74) 00.137(99.28) 000.59(98.33) - 0.157
Antiarrhythmic drugs 0.0081(86.17) 00.119(86.23) 000.54(90.00) 00.606 0.739
a:indicates that compared with the patients in the non⁃frail group,the difference is statistically significant(P < 0.05);b:indicates that compared
with the patients in the pre⁃frail group,the difference is statistically significant(P < 0.05). AF:atrial fibrillation;BMI:body mass index;FPG:fasting
plasma glucose;HbA1c:hemoglobin A1c;Scr:serum creatinine;UA:uric acid;TC:total cholesterol;TG:triglyceride;HDL⁃C:high⁃density lipoprotein
cholesterol;LDL⁃C:low⁃density lipoprotein cholesterol;NT⁃proBNP:N⁃terminal pro⁃B⁃type natriuretic peptide;hs⁃cTnT:high⁃sensitivity cardiac tropo⁃
nin T;ALB:albumin;LAD:left atrial diameter;LVDd:left ventricular diastolic dimension;LVDs:left ventricular systolic dimension;LVEF:left ventric⁃
ular ejection fraction;ACEI:angiotensin⁃converting enzyme inhibitor;ARB:angiotensin Ⅱ receptor blockers;CCB:calcium channel blocker.

