Page 75 - 南京医科大学自然版

第45卷第6期 徐思雨，张永杰，田 水，等. 深度学习重建算法在胰腺HASTE⁃T2WI序列中的临床应用价值［J］.
2025年6月 南京医科大学学报（自然科学版），2025，45（6）：810-815，825 ·813 ·

1 500 ***
*** BLADE⁃TSE
HASTE⁃DL

1 000
***
A B
A：BLADE⁃TSE sequence. B：HASTE⁃DL sequence. The signal is
500
missing due to the intestinal air motion artifact in A（arrow above），and
image B has slightly better artifact suppression. The lesion and pancreat⁃
ic duct in B have higher SNR and sharper contrast.
0
图4 1例胰腺导管内乳头状黏液瘤68岁女性患者病灶检测
SNRpancreas SNRlesions CNR CNRlesions/normal tissue
比较图
The SNR and CNR of HASTE⁃DL sequence was higher than that of
Figure 4 Comparison of lesion detection in a 68⁃year⁃old
BLADE⁃TSE sequence. *** P < 0.01.
图2 SNR和CNR定量比较散点柱状统计图 female patient with IPMN of the pancreas
Figure 2 Scattered ⁃ column statistical chart for quantita-
tive comparison of SNR and CNR

表2 HASTE⁃DL和BLADE⁃TSE图像定量比较
Table 2 Quantitative comparison of HASTE ⁃ DL and
BLADE⁃TSE images （x ± s）
A B
Sequence SNRpancreas SNRlesions CNRlesions/normal tissue A：BLADE⁃TSE sequence. B：HASTE⁃DL sequence. Both A and B
HASTE⁃DL 166.65±81.90 568.45±370.37 417.47±346.85 can clearly see the lesion（arrow below）；the contrast between pancreatic
BLADE⁃TSE 87.78±37.86 213.34±134.78 133.46±118.66 duct and lesion in B is sharper and the lesion boundary is clearer，which
t <9.123 <9.343 <8.230 is conducive to the display and measurement of lesion. Both sets of se⁃
P <0.001 <0.001 <0.001 quences had comparable artifact suppression（arrow above）.
图 5 1 例多发胰腺导管内乳头状黏液瘤（IPMN）34 岁女性
患者病灶检测比较图
Figure 5 Comparison of lesion detection in a 34⁃year⁃old
female patient with multiple IPMN of the pan-
creas

间，探讨 DL 在胰腺 MRI 临床应用中的价值。本研
A B 究结果显示，HASTE⁃DL⁃T2WI序列能够获得优于常
A：BLADE⁃TSE sequence. B：HASTE⁃DL sequence. The loss of sig⁃ 规 BLADE⁃TSE⁃T2WI 序列的胰腺 T2WI 图像，图像
nal interference caused by artifacts in A is slightly more serious than
SNR 和 CNR 更高，组织之间的锐利度更加优秀，伪
that in B（arrow above）. Pancreatic duct lesions in B showed sharper，
影控制两者相当，并且大幅度减少扫描时间，能够
and bile duct clarity showed better than A（arrow below）.
图3 1 例胰腺尾部囊性病灶的 45 岁男性患者病灶检测比 为不能耐受长时间检查和呼吸配合较差的患者提
较图 供另一种扫描选择，有较高的临床应用价值。
Figure 3 Comparison of lesion dection in a 45 ⁃ year ⁃ old 3.1 HASTE⁃DL 序列相比 BLADE⁃TSE 序列的扫描
male patient with a cystic lesion in the pancreatic 时间优势
tail 目前临床上胰腺 MRI 的 BLADE⁃TSE⁃T2WI 序
列为运用刀锋伪影校正（BLADE）技术的TSE 序列，
3 讨 论
BLADE技术采用螺旋桨式K空间数据填充，可以减
本研究通过比较 HASTE⁃DL 序列和 BLADE⁃ 少运动伪影、提高图像质量，但这种采集模式会增
TSE序列胰腺T2WI的图像质量，包括胰腺和病灶组 加数据采集量，重复冗余的数据采集导致扫描时间
织 SNR、病灶 CNR、总体图像质量、胰腺锐利度、胆 长 ［13］ ，特别是应用在胰腺 MRI 时，需要薄层（3 mm）
管显示清晰度、伪影以及病灶检出效能和扫描时 扫描才能满足临床诊断胰腺所需的分辨率，因此不