Page 92 - 南京医科大学自然版
P. 92
第46卷第10期
·1522 · 南 京 医 科 大 学 学 报 2026年10月
表2 非转移和转移淋巴结的CT图像特征比较
Table 2 Comparison of CT image features between non⁃metastatic lymph nodes and metastatic lymph nodes
Training set(n=531) Validation set(n=246)
Non⁃metastatic Metastatic Non⁃metastatic Metastatic
CT image features Z/χ 2 P Z/χ 2 P
lymph node lymph node lymph node lymph node
(n=281) (n=250) (n=117) (n=129)
Size[mm,M(P25,P75)] 5.10(3.95,6.10) 6.35(4.70,8.80) 6.719 <0.001 5.00(3.65,5.80) 7.40(5.10,10.90) 6.718 <0.001
Regular shape[n(%)] .222(79.0) .162(64.8) 13.332 <0.001 0.94(80.3) 0.85(65.9) 6.465 0.011
Well⁃defined margin[n(%)] .228(81.1) .181(72.4) 5.709 0.017 0.97(83.0) 0.93(73.1) 4.080 0.043
Marked early enhancement[n(%)] .073(26.0) .200(80.0) 154.557 <0.001 0.30(25.6) .105(81.4) 77.021 <0.001
Calcification[n(%)] .001(0.4) .017(6.8) 16.776 <0.001 0.01(0.9) .025(19.4) 22.276 <0.001
Cystic change[n(%)] .000(0) .021(8.4) 24.576 <0.001 0.01(0.9) .011(8.5) 7.784 0.005
Extranodal extension[n(%)] .000(0) .007(2.8) 7.973 0.005 0.00(0) .001(0.8) 0.911 0.340
表3 非转移和转移淋巴结的DECT定量参数比较
Table 3 DECT quantitative parameters between non⁃metastatic and metastatic lymph nodes
Training set(n=531)
Quantitative parameter Z/t P
Non⁃metastatic lymph node(n=281) Metastatic lymph node(n=250)
Arterial phase IC[mg/mL,M(P25,P75)] 1.600(1.000,2.300) 3.200(2.700,4.200) 015.559 <0.001
Arterial phase NIC[M(P25,P75)] 0.161(0.104,0.218) 0.360(0.285,0.467) 015.895 <0.001
Arterial phase Zeff[M(P25,P75)] 8.300(8.015,8.645) 9.085(8.800,9.423) 015.013 <0.001
Arterial phase NZeff[M(P25,P75)] 0.729(0.697,0.757) 0.820(0.782,0.862) 015.757 <0.001
Arterial phase λHU[M(P25,P75)] 2.703(1.892,3.923) 5.690(4.255,7.641) 013.654 <0.001
Venous phaseIC[mg/mL,M(P25,P75)] 2.300(1.700,2.800) 3.000(2.400,3.600) 010.485 <0.001
Venous phase NIC[M(P25,P75)] 0.426(0.342,0.512) 0.608(0.507,0.730) 011.583 <0.001
Venous phase Zeff[M(P25,P75)] 8.600(8.440,8.800) 8.970(8.788,9.303) 011.715 <0.001
Venous phase λHU[M(P25,P75)] 3.933(3.195,4.712) 5.248(4.402,6.456) 011.050 <0.001
Venous phase NZeff(x ± s) 0.866 ± 0.040 0.922 ± 0.044 409.033 <0.001
Validation set(n=246)
Quantitative parameter Z/t P
Non⁃metastatic lymph node(n=117) Metastatic lymph node(n=129)
Arterial phase IC[mg/mL,M(P25,P75)] 1.400(1.000,1.900) 3.800(3.000,4.500) 011.395 <0.001
Arterial phase NIC[M(P25,P75)] 0.144(0.097,0.218) 0.376(0.297,0.553) 011.064 <0.001
Arterial phase Zeff[M(P25,P75)] 8.230(7.915,8.510) 9.280(8.895,9.700) 010.955 <0.001
Arterial phase NZeff[M(P25,P75)] 0.736(0.689,0.771) 0.823(0.791,0.876) 010.293 <0.001
Arterial phase λHU[M(P25,P75)] 2.403(1.462,3.788) 6.797(4.402,9.127) 010.061 <0.001
Venous phaseIC[mg/mL,M(P25,P75)] 2.300(1.750,2.850) 3.600(2.750,4.400) 008.527 <0.001
Venous phase NIC[M(P25,P75)] 0.475(0.356,0.593) 0.667(0.545,0.800) 007.284 <0.001
Venous phase Zeff[M(P25,P75)] 8.660(8.395,8.820) 9.250(8.850,9.580) 009.129 <0.001
Venous phase λHU[M(P25,P75)] 4.057(3.055,5.005) 6.140(4.902,7.620) 008.330 <0.001
Venous phase NZeff(x ± s) 0.875 ± 0.049 0.931 ± 0.047 256.011 <0.001
灰度共生矩阵相关动脉期梯度灰度共生矩阵Imc2、 调、动脉期对数σ=1.0 mm 三维灰度行程长矩阵⁃长
动脉期梯度灰度差分矩阵依赖方差、动脉期梯度灰 行程低灰度级强调、动脉期对数σ=1.0 mm三维灰度
度差分矩阵大依赖高灰度级强调度、动脉期对数灰 行程长矩阵⁃短行程低灰度级强调、动脉期小波⁃
度大小区域矩阵灰度级非均匀度归一化值、动脉期 LHL灰度尺寸区域矩阵⁃小区域低灰度级强调、动脉
对数灰度差分矩阵依赖方差、动脉期平方一阶矩偏 期小波⁃HLL 灰度共生矩阵⁃相关性、动脉期小波⁃
度、动脉期平方灰度行程长矩阵⁃短行程低灰度级强 HLH 灰度尺寸区域矩阵⁃大面积低灰度级强调、动

