Page 30 - 南京医科大学自然版
P. 30

第46卷第4期
               ·498 ·                            南 京    医 科 大 学 学         报                        2026年4月


             [46]CHEN X Y,SAIYIN H,LIU Y,et al. Human striatal       Circuit mechanisms of neurodegenerative diseases:a new
                   organoids derived from pluripotent stem cells recapitulate  frontier with miniature fluorescence microscopy[J]. Front
                   striatal development and compartments[J]. PLoS Biol,  Neurosci,2019,13:1174
                   2022,20(11):e3001868                         [53]CRITTENDEN J R,GRAYBIEL A M. Basal ganglia disor⁃
             [47]LIU C Y,FU Z X,WU S S,et al. Mitochondrial HSF1 trig⁃  ders associated with imbalances in the striatal striosome
                   gers mitochondrial dysfunction and neurodegeneration in  and matrix compartments[J]. Front Neuroanat,2011,5:59
                   Huntington’s disease[J]. EMBO Mol Med,2022,14(7):  [54]QUADRATO G,NGUYEN T,MACOSKO E Z,et al. Cell
                   e15851                                            diversity and network dynamics in photosensitive human
             [48]WU S S,HONG Y,CHU C,et al. Construction of human    brain organoids[J]. Nature,2017,545(7652):48-53
                   3D striato⁃nigral assembloids to recapitulate medium spiny  [55]VELASCO S,KEDAIGLE A J,SIMMONS S K,et al. Indi⁃
                   neuronal projection defects in Huntington’s disease[J].  vidual brain organoids reproducibly form cell diversity of
                   Proc Natl Acad Sci USA,2024,121(22):e2316176121   the human cerebral cortex[J]. Nature,2019,570(7762):
             [49]FAN P,LIU Y Q,LIU C Y,et al. NEDD4L induces mito⁃   523-527
                   chondrial dysfunction and neurodegeneration by promo ⁃  [56]XU L,DING H B,WU S S,et al. Artificial meshed vessel⁃
                   ting LIPT2 degradation in Huntington’s disease[J]. Proc  induced dimensional breaking growth of human brain
                   Natl Acad Sci USA,2025,122(29):e2503342122        organoids and multiregional assembloids[J]. ACS Nano,
             [50]LIU Y,CHEN X Y,MA Y L,et al. Endogenous mutant      2024,18(38):26201-26214
                   Huntingtin alters the corticogenesis via lowering Golgi re⁃  [57]ZHU Y J,ZHANG X X,SUN L Y,et al. Engineering hu⁃
                   cruiting ARF1 in cortical organoid[J]. Mol Psychiatry,  man brain assembloids by microfluidics[J]. Adv Mater,
                   2024,29(10):3024-3039                             2023,35(14):e2210083
             [51]LISOWSKI P,LICKFETT S,RYBAK⁃WOLF A,et al. Mu⁃  [58]SUN X Y,JU X C,LI Y,et al. Generation of vascularized
                   tant huntingtin impairs neurodevelopment in human brain  brain organoids to study neurovascular interactions[J].
                   organoids through CHCHD2 ⁃ mediated neurometabolic  Elife,2022,11:e76707
                   failure[J]. Nat Commun,2024,15(1):7027        (收稿:2025-08-18;修回:2025-09-29;录用:2025-10-11)
             [52]WERNER C T,WILLIAMS C J,FERMELIA M R,et al.                                  (本文编辑:陈汐敏)







                                                                                                            




                             我刊现已启用网上稿件管理系统,作者登陆


                           http:∥jnmu.njmu.edu.cn/即可在线投稿并查询

                           稿件审理情况。






                     
   25   26   27   28   29   30   31   32   33   34   35