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               · 74  ·                           南 京    医 科 大 学 学         报                        2022年1月


              患者较低的获卵数和妊娠率可能与其第1次ART周                                dex:analysis of 239,127 fresh autologous in vitro fertiliza⁃
              期保守治疗剂量相关,同时,肥胖组患者年龄相对较                                tion cycles from the 2008⁃2010 society for assisted repro⁃
              大,也可能是潜在原因之一,需要进一步研究分析。                                ductive technology registry[J]. Fertil Steril,2016,105
                                                                    (3):663-669
                  总之,本研究结果表明肥胖降低了第 1 次 IVF/
              ICSI 周期患者的鲜胚种植率,活产率有降低的趋势,                        [12] CHEN R,CHEN S,LIU M,et al. Pregnancy outcomes of
                                                                     PCOS overweight/obese patients after controlled ovarian
              同时流产率也有增加趋势。本研究结果有助于临床
                                                                     stimulation with the GnRH antagonist protocol and frozen
              上对超重患者的咨询和教育,指导患者进行有益的生
                                                                     embryo transfer[J]. Reprod Biol Endocrinol,2018,16
              活方式并减轻体重以达到理想的ART治疗结局。
                                                                    (1):36
             [参考文献]                                             [13] LUKE B,BROWN M B,STERN J E,et al. Female obesi⁃
                                                                     ty adversely affects assisted reproductive technology
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