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第43卷第9期 甘宇婧,史如鹏,吴丹瑛,等. 老年脓毒症患者早期炎症因子水平及预后的相关性分析[J].
2023年9月 南京医科大学学报(自然科学版),2023,43(9):1208-1215 ·1211 ·
表2 老年脓毒症患者与青壮年脓毒症患者相关指标的比较
Table 2 The comparison of inflammatory factors between elderly group and young adult group in patients with sepsis
WBC[×10 个/L, PCT[ng/mL, CRP[mg/L, IL⁃2[pg/mL, IL⁃4[pg/mL, IL⁃6[pg/mL,
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组别
M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )]
老年组(n=98) 10.00(6.84,13.63)0.67(0.25,5.12)79.75(28.70,149.25)1.63(0.46,4.45)1.32(0.31,2.62)93.78(27.22,399.70)
青壮年组(n=37)11.52(7.66,16.67)0.45(0.12,2.65)72.90(22.75,105.50)1.64(0.19,4.00)0.66(0.01,2.48)69.78(19.31,231.58)
t/z值 -1.347 -1.815 -1.078 ⁃0.351 -1.202 -1.334
P值 -0.178 -0.690 -0.281 ⁃0.725 -0.229 -0.182
IL⁃10[pg/mL, TNF⁃α[pg/mL, IFN⁃γ[pg/mL, PLT[×10 个/L, Lym[×10 个/L, APACHE Ⅱ
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组别
M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] (分,x ± s)
老年组(n=98) 3.63(1.94,8.96) 0.82(0.23,2.17) 0.30(0.01,0.88) 127.50(94.00,190.25) 0.80(0.56,1.10) 22.37 ± 5.23
青壮年组(n=37) 3.36(1.62,7.73) 1.10(0.01,3.07) 0.09(0.01,0.96) 163.00(115.00,259.00) 1.22(0.71,1.58) 17.50 ± 4.41
t/z值 -0.397 -0.342 -0.569 -2.254 -2.548 -4.440
P值 -0.691 -0.733 -0.569 -0.024 -0.011 <0.001
表3 老年脓毒症患者脓毒症休克组与脓毒症组炎症因子比较
Table 3 The comparison of inflammatory factors between septic shock group and septic group in elderly patients with sepsis
[M(P25,P75 )]
组别 WBC(×10 个/L) PCT(ng/mL) CRP(mg/L) IL⁃2(pg/mL)
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脓毒症休克组(n=27) 09.89(7.60,19.30) 3.82(0.83,16.55) 142.00(78.70,223.00) 1.54(0.37,4.67)
脓毒症组(n=71) 10.01(6.83,13.23) 0.44(0.21,2.14) 072.70(17.90,118.00) 1.65(0.58,4.38)
t/z值 -0.871 -3.944 -3.451 -0.578
P值 -0.384 <0.001 -0.001 -0.563
组别 IL⁃4(pg/mL) IL⁃6(pg/mL) IL⁃10(pg/mL) TNF⁃α(pg/mL)
脓毒症休克组(n=27) 1.32(0.10,2.36) 241.59(23.80,740.67) 5.00(2.79,10.65) 0.48(0.02,2.05)
脓毒症组(n=71) 1.36(0.43,2.76) 073.16(27.25,293.12) 3.17(1.93,5.97) 0.94(0.30,2.53)
t/z值 -0.611 -1.332 -1.547 -1.136
P值 -0.541 -0.183 -0.122 -0.256
组别 IFN⁃γ(pg/mL) PLT(×10 个/L) Lym(×10 个/L) APACHE Ⅱ(分)
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脓毒症休克组(n=27) 0.12(0.01,0.81) 098.00(50.00,145.00) 0.88(0.54,1.09) 27.00(20.50,30.00)
脓毒症组(n=71) 0.40(0.01,1.01) 146.00(98.00,205.00) 0.77(0.57,1.11) 21.00(18.00,24.00)
t/z值 -1.408 -2.851 -0.298 -2.998
P值 -0.159 -0.004 -0.766 -0.003
表4 老年脓毒症患者存活组与死亡组炎症因子比较
Table 4 The comparison of inflammatory factors between survival group and death group in elderly patients with sepsis
WBC[×10 个/L, PCT[ng/mL, CRP[mg/L, IL⁃2[pg/mL, IL⁃4[pg/mL, IL⁃6[pg/mL,
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组别
M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )]
存活组(n=66)09.36(6.82,13.14)0.64(0.20,4.17)077.25(20.75,143.00)1.94(0.45,5.07)1.29(0.29,2.74)89.76(23.41,381.95)
死亡组(n=32)10.93(7.39,15.62)1.98(0.38,7.56)100.55(35.38,159.50)1.54(0.56,2.22)1.32(0.30,2.38)99.64(45.26,583.41)
t/z值 -0.773 -1.735 -1.402 -1.052 -0.536 -1.023
P值 -0.440 -0.083 -0.161 -0.293 -0.592 -0.306
IL⁃10[pg/mL, TNF⁃α[pg/mL, IFN⁃γ[pg/mL, PLT[×10 个/L, Lym[×10 个/L, APACHE Ⅱ
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组别
M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] M(P25,P75 )] (分,x ± s)
存活组(n=66) 3.17(1.85,5.66) 0.79(0.28,1.86) 0.34(0.01,0.83) 121.50(92.50,195.25) 0.81(0.59,1.11) 21.14 ± 5.14
死亡组(n=32) 4.43(2.21,10.46) 0.91(0.15,3.73) 0.04(0.01,1.04) 132.50(98.25,182.25) 0.77(0.49,1.09) 24.91 ± 4.52
t/z值 -1.890 -0.034 -0.648 -0.379 -0.921 -3.530
P值 -0.059 -0.973 -0.517 -0.705 -0.357 -0.001