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第43卷第9期          甘宇婧,史如鹏,吴丹瑛,等. 老年脓毒症患者早期炎症因子水平及预后的相关性分析[J].
                  2023年9月                     南京医科大学学报(自然科学版),2023,43(9):1208-1215                      ·1211 ·


                                         表2 老年脓毒症患者与青壮年脓毒症患者相关指标的比较
                  Table 2 The comparison of inflammatory factors between elderly group and young adult group in patients with sepsis
                              WBC[×10 个/L, PCT[ng/mL,      CRP[mg/L,     IL⁃2[pg/mL,  IL⁃4[pg/mL,  IL⁃6[pg/mL,
                                     9
                     组别
                               M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]
                老年组(n=98) 10.00(6.84,13.63)0.67(0.25,5.12)79.75(28.70,149.25)1.63(0.46,4.45)1.32(0.31,2.62)93.78(27.22,399.70)
                青壮年组(n=37)11.52(7.66,16.67)0.45(0.12,2.65)72.90(22.75,105.50)1.64(0.19,4.00)0.66(0.01,2.48)69.78(19.31,231.58)
                t/z值             -1.347        -1.815        -1.078        ⁃0.351      -1.202        -1.334
                P值               -0.178        -0.690        -0.281        ⁃0.725      -0.229        -0.182
                               IL⁃10[pg/mL,  TNF⁃α[pg/mL, IFN⁃γ[pg/mL,   PLT[×10 个/L,     Lym[×10 个/L, APACHE Ⅱ
                                                                                                9
                                                                                9
                     组别
                                M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]   M(P25,P75 )]    M(P25,P75 )]  (分,x ± s)
                老年组(n=98)     3.63(1.94,8.96) 0.82(0.23,2.17) 0.30(0.01,0.88) 127.50(94.00,190.25) 0.80(0.56,1.10) 22.37 ± 5.23
                青壮年组(n=37) 3.36(1.62,7.73) 1.10(0.01,3.07) 0.09(0.01,0.96) 163.00(115.00,259.00) 1.22(0.71,1.58) 17.50 ± 4.41
                t/z值              -0.397       -0.342       -0.569           -2.254          -2.548      -4.440
                P值                -0.691       -0.733       -0.569           -0.024          -0.011     <0.001


                                        表3 老年脓毒症患者脓毒症休克组与脓毒症组炎症因子比较
                Table 3 The comparison of inflammatory factors between septic shock group and septic group in elderly patients with sepsis
                                                                                                    [M(P25,P75 )]
                       组别              WBC(×10 个/L)         PCT(ng/mL)           CRP(mg/L)          IL⁃2(pg/mL)
                                               9
                 脓毒症休克组(n=27)          09.89(7.60,19.30)  3.82(0.83,16.55)   142.00(78.70,223.00)  1.54(0.37,4.67)
                 脓毒症组(n=71)            10.01(6.83,13.23)   0.44(0.21,2.14)   072.70(17.90,118.00)  1.65(0.58,4.38)
                 t/z值                      -0.871              -3.944              -3.451             -0.578
                 P值                        -0.384             <0.001               -0.001             -0.563
                       组别               IL⁃4(pg/mL)          IL⁃6(pg/mL)         IL⁃10(pg/mL)      TNF⁃α(pg/mL)
                 脓毒症休克组(n=27)          1.32(0.10,2.36)   241.59(23.80,740.67)   5.00(2.79,10.65)   0.48(0.02,2.05)
                 脓毒症组(n=71)            1.36(0.43,2.76)   073.16(27.25,293.12)   3.17(1.93,5.97)    0.94(0.30,2.53)
                 t/z值                      -0.611              -1.332               -1.547            -1.136
                 P值                        -0.541              -0.183               -0.122            -0.256
                       组别              IFN⁃γ(pg/mL)        PLT(×10 个/L)        Lym(×10 个/L)      APACHE Ⅱ(分)
                                                                                      9
                                                                  9
                 脓毒症休克组(n=27)          0.12(0.01,0.81)  098.00(50.00,145.00)   0.88(0.54,1.09)  27.00(20.50,30.00)
                 脓毒症组(n=71)            0.40(0.01,1.01)  146.00(98.00,205.00)   0.77(0.57,1.11)  21.00(18.00,24.00)
                 t/z值                     -1.408              -2.851              -0.298             -2.998
                 P值                       -0.159              -0.004              -0.766             -0.003


                                            表4 老年脓毒症患者存活组与死亡组炎症因子比较
                 Table 4 The comparison of inflammatory factors between survival group and death group in elderly patients with sepsis

                            WBC[×10 个/L, PCT[ng/mL,       CRP[mg/L,     IL⁃2[pg/mL,  IL⁃4[pg/mL,   IL⁃6[pg/mL,
                                    9
                    组别
                              M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]   M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]
                存活组(n=66)09.36(6.82,13.14)0.64(0.20,4.17)077.25(20.75,143.00)1.94(0.45,5.07)1.29(0.29,2.74)89.76(23.41,381.95)
                死亡组(n=32)10.93(7.39,15.62)1.98(0.38,7.56)100.55(35.38,159.50)1.54(0.56,2.22)1.32(0.30,2.38)99.64(45.26,583.41)
                t/z值            -0.773       -1.735         -1.402         -1.052      -0.536        -1.023
                P值              -0.440       -0.083         -0.161         -0.293      -0.592        -0.306
                              IL⁃10[pg/mL,  TNF⁃α[pg/mL,  IFN⁃γ[pg/mL,   PLT[×10 个/L,    Lym[×10 个/L, APACHE Ⅱ
                                                                                9
                                                                                                9
                    组别
                               M(P25,P75 )]  M(P25,P75 )]  M(P25,P75 )]    M(P25,P75 )]    M(P25,P75 )]  (分,x ± s)
                存活组(n=66) 3.17(1.85,5.66)  0.79(0.28,1.86) 0.34(0.01,0.83) 121.50(92.50,195.25) 0.81(0.59,1.11) 21.14 ± 5.14
                死亡组(n=32) 4.43(2.21,10.46) 0.91(0.15,3.73) 0.04(0.01,1.04) 132.50(98.25,182.25) 0.77(0.49,1.09) 24.91 ± 4.52
                t/z值             -1.890        -0.034       -0.648          -0.379          -0.921       -3.530
                P值               -0.059        -0.973       -0.517          -0.705          -0.357       -0.001
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