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第44卷第8期 裴桐忻，张克忠，鲁 严. 一氧化氮在神经精神疾病中作用的研究进展［J］.
2024年8月 南京医科大学学报（自然科学版），2024，44（8）：1155-1164 ·1163 ·

phenylpropenoyl⁃l⁃amino acids as potent and selective in⁃ ord，2020，38：101873
ducible nitric oxide synthase inhibitors for Parkinson’s ［66］WIGNER P，DZIEDZIC A，SYNOWIEC E，et al. Varia⁃
Disease［J］. J Med Chem，2021，64（11）：7760-7777 tion of genes encoding nitric oxide synthases and antioxi⁃
［54］AGRAWAL S，KUMARI R，SOPHRONEA T，et al. De⁃ dant enzymes as potential risks of multiple sclerosis devel⁃
sign and synthesis of benzo［d］thiazol⁃2⁃yl⁃methyl⁃4⁃（sub⁃ opment：a preliminary study［J］. Sci Rep，2022，12（1）：
stituted）⁃piperazine⁃1⁃carbothioamide as novel neuronal 10603
nitric oxide inhibitors and evaluation of their neuropro⁃ ［67］BÖ L，DAWSON T M，WESSELINGH S，et al. Induction
tecting effect in 6⁃OHDA⁃induced unilateral lesioned rat of nitric oxide synthase in demyelinating regions of multi⁃
model of Parkinson’s disease［J］. Biomed Pharmacother， ple sclerosis brains［J］. Ann Neurol，1994，36（5）：778-
2022，156：113838 786
［55］SANTOS⁃LOBATO B L，BORTOLANZA M，PINHEIRO ［68］SCHEPERS M，PAES D，TIANE A，et al. Selective PDE4
L C，et al. Levodopa⁃induced dyskinesias in Parkinson’s subtype inhibition provides new opportunities to inter⁃
disease increase cerebrospinal fluid nitric oxide metabo⁃ vene in neuroinflammatory versus myelin damaging hall⁃
lites’levels［J］. J Neural Transm，2022，129（1）：55-63 marks of multiple sclerosis［J］. Brain Behav Immun，
［56］BARMAKI H，MOROVATI A，EYDIVANDI Z，et al. The 2023，109：1-22
association between serum oxidative stress indexes and ［69］LIU J S，ZHAO M L，BROSNAN C F，et al. Expression of
pathogenesis of Parkinson’s disease in the northwest of inducible nitric oxide synthase and nitrotyrosine in multi⁃
Iran［J］. Iran J Public Health，2021，50（3）：606-615 ple sclerosis lesions［J］. Am J Pathol，2001，158（6）：
［57］BREMBATI V，FAUSTINI G，LONGHENA F，et al. 2057-2066
Changes in α⁃synuclein posttranslational modifications in ［70］GIOVANNONI G. Cerebrospinal fluid and serum nitric
an AAV⁃based mouse model of Parkinson’s disease［J］. oxide metabolites in patients with multiple sclerosis［J］.
Int J Mol Sci，2023，24（17）：13435 Mult Scler，1998，4（1）：27-30
［58］YU Z，XU X，XIANG Z，et al. Nitrated alpha⁃synuclein in⁃ ［71］MALABENDU J ，KALIPADA P. Down ⁃ regulation of
duces the loss of dopaminergic neurons in the substantia myelin gene expression in human oligodendrocytes by
nigra of rats［J］. PLoS One，2010，5（4）：e9956 nitric oxide：implications for demyelination in multiple
［59］朱睿放，张 宇，卢应梅. 小胶质细胞及其介导的神经 sclerosis［J］. J Clin Cell Immunol，2013，4：10
炎症在帕金森病中的作用［J］. 南京医科大学学报（自 ［72］TANG X，LAN M，ZHANG M，et al. Effect of nitric oxide

然科学版），2023，43（4）：569-576 to axonal degeneration in multiple sclerosis via downregu⁃
［60］KIM J，HAN J Y，LEE Y，et al. Genetic deletion of nitric lating monocarboxylate transporter 1 in oligodendro⁃
oxide synthase 2 ameliorates Parkinson’s disease pathology cytes［J］. Nitric Oxide，2017，67：75-80
and neuroinflammation in a transgenic mouse model of ［73］BONILLA⁃JAIME H，SANCHEZ⁃SALCEDO J A，ESTE⁃
synucleinopathy［J］. Mol Brain，2023，16（1）：7 VEZ⁃CABRERA M M，et al. Depression and pain：use of
［61］ARA J，PRZEDBORSKI S，NAINI A B，et al. Inactivation antidepressants［J］. Curr Neuropharmacol，2022，20（2）：
of tyrosine hydroxylase by nitration following exposure to 384-402
peroxynitrite and 1⁃methyl⁃4⁃phenyl⁃1，2，3，6⁃tetrahydro⁃ ［74］BASKIN V，EROGLU E，HARMANCI N，et al. Antinoci⁃
pyridine（MPTP）［J］. Proc Natl Acad Sci U S A，1998，95 ceptive，anxiolytic，and depression⁃like effects of hydro⁃
（13）：7659-7663 gen sulfide，nitric oxide，and carbon monoxide in rats and
［62］ZHONG Y，LI X，DU X，et al. The S⁃nitrosylation of par⁃ the role of opioidergic and serotonergic systems in antino⁃
kin attenuated the ubiquitination of divalent metal trans⁃ ciceptive activity［J］. Fundam Clin Pharmacol，2022，36
porter 1 in MPP ⁃treated SH⁃SY5Y cells［J］. Sci Rep， （4）：674-686
+
2020，10（1）：15542 ［75］YANG T，WANG J，HUANG J，et al. Long⁃term exposure
［63］MARCUS R. What is multiple sclerosis?［J］. JAMA，2022， to multiple ambient air pollutants and association with in⁃
328（20）：2078 cident depression and anxiety［J］. JAMA Psychiatry，
［64］AMIN M，HERSH C M. Updates and advances in multi⁃ 2023，80（4）：305-313
ple sclerosis neurotherapeutics［J］. Neurodegener Dis ［76］OSHNOKHAH M，BAGHERI M，GHANEIALVAR H，et
Manag，2023，13（1）：47-70 al. The role of oxidant⁃antioxidant status in suicide beha⁃
［65］ABDEL N M，RABAH A M，RASHED L A，et al. Gluta⁃ vior in kurdish ethnicity［J］. Basic Clin Neurosci，2021，
mate and nitric oxide as biomarkers for disease activity in 12（5）：667-674
patients with multiple sclerosis［J］. Mult Scler Relat Dis⁃ ［77］MCNEILL R V，KEHRWALD C，BRUM M，et al. Unco⁃