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第45卷第11期
·1630 · 南 京 医 科 大 学 学 报 2025年11月
表2 高TyG指数与低TyG指数患者的超声心动图参数对比
Table 2 Comparison of echocardiographic parameters between patients with high and low TyG index (x ± s)
Echocardiographic parameters Total(n=103) High TyG(n=52) Low TyG(n=51) t/z P
LAD(mm,x ± s) 33.45 ± 4.33 34.58 ± 4.21 32.29 ± 4.18 2.763 <0.01
LVD(mm,x ± s) 47.17 ± 3.80 47.19 ± 3.62 47.16 ± 4.00 0.047 <0.963
LVEF(%,x ± s) 67.02 ± 3.90 66.28 ± 4.12 67.78 ± 3.54 -1.989 <0.049
Septal thickness(mm,x ± s) 0 9.74 ± 1.41 10.17 ± 1.41 0 9.29 ± 1.27 3.322 <0.05
Posterior wall thickness(mm,x ± s) 0 9.14 ± 0.98 0 9.38 ± 0.99 0 8.88 ± 0.91 2.676 <0.01
GLS(%,x ± s) -18.70 ± 2.64 -17.60 ± 2.65 -19.82 ± 2.12 4.678 <0.01
GWI(mmHg%,x ± s) 1 801.06 ± 321.21 1 672.33 ± 308.58 1 932.31 ± 280.26 -4.474 <0.01
GCW(mmHg%,x ± s) 2 147.87 ± 355.59 1 999.46 ± 324.11 2 299.20 ± 323.32 -4.698 <0.01
GWW[mmHg%,M(P25,P75)] 100.23(60.02,153.00) 101.51(61.76,155.32) 98.02(58.91,150.98) 0.410 <0.357
GWE(%,x ± s) 94.37 ± 2.84 93.90 ± 3.48 94.84 ± 1.91 -1.694 <0.093
E(m/s,x ± s) 0 0.71 ± 0.18 0 0.68 ± 0.20 0 0.74 ± 0.16 -1.657 <0.101
A(m/s,x ± s) 0 0.77 ± 0.17 0 0.78 ± 0.18 0 0.77 ± 0.16 0.330 <0.742
E/A 0 0.96 ± 0.34 0 0.91 ± 0.33 0 1.01 ± 0.35 -1.437 <0.154
Septale’(cm/s,x ± s) 0 7.33 ± 2.56 0 6.48 ± 2.00 0 8.20 ± 2.80 -3.586 <0.01
Laterale’(cm/s,x ± s) 10.55 ± 3.28 0 9.62 ± 3.08 11.51 ± 3.23 -3.047 <0.01
E/e’(x ± s) 0 8.69 ± 2.15 0 9.20 ± 2.21 0 8.17 ± 1.98 2.495 <0.05
LVMI(g/m ,x ± s) 0 85.67 ± 14.08 0 86.43 ± 12.84 0 84.90 ± 15.34 0.547 <0.585
2
RWT(x ± s) 0 0.39 ± 0.05 00 0.40 ± 0.050 0 0.37 ± 0.05 2.762 <0.01
LAD:left atrialdimension;LVD:left ventricularend diastolic dimension;LVEF:left ventricular ejection fraction;GLS:global longitudinal strain;
GWI:global work index;GCW:global constructive work;GWW:global wasted work;GWE:global work efficiency;LVMI:left ventricular mass index.
A B
C D
A:LV GLS(-21.4%)corresponding to a low TyG index(TyG=7.8). B:LV GLS(-16.2%)corresponding to a high TyG index(TyG=9.0). C:LV
pressure⁃strain loop curve corresponding to a low TyG index(TyG=7.8). D:LV pressure⁃strain loop curve corresponding to a high TyG index(TyG=9.0).
图1 TyG指数对应的左心室GLS与左室心肌做功牛眼图
Figure 1 Representative left ventricular GLS and myocardial work polar maps stratified by TyG index
AUC=0.725(95% CI:0.622~0.828,最 佳 截 断 值 为 AUC=0.697(95% CI:0.595~0.799,最 佳 截 断 值 为
8.656,特异度为60.6%,灵敏度为75%,P < 0.001,图 8.656,特异度为 68.6%,灵敏度为 69.2%,P=0.001,
2A)。TyG 指数是预测 GWI 降低的独立危险因素, 图2B)。TyG指数是预测GCW降低的独立危险因素

