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第45卷第5期 南京医科大学学报(自然科学版)
2025年5月 Journal of Nanjing Medical University(Natural Sciences) ·699 ·
·综 述·
机器人支气管镜应用进展
陈淑娟 ,方申存 ,侯志波 1,2*
1,2
1
南京医科大学附属脑科医院呼吸内科,江苏 南京 210029;南京市胸科医院内镜中心,江苏 南京 210029
1 2
[摘 要] 随着低剂量计算机断层扫描的广泛应用,肺外周病变(peripheral pulmonary lesion,PPL)的检出率正逐年提高。为进
一步明确PPL的性质,需对PPL进行组织活检以获得病理诊断。PPL远离中央气道且靠近胸膜,常规支气管镜难以到达,诊断率和
灵敏度都不理想。虽然经皮肺穿刺活检诊断率有所提高,但具有较高的并发症。机器人支气管镜(robotic⁃assisted bronchoscopy,
RAB)是用于诊断肺部病变的新技术,提高了导航的精确度,扩大了镜头的可达范围,具有更高的准确性、稳定性、灵活性等优
势,较传统支气管镜诊断率更高、安全性更大。RAB 还可作为介入平台与现有消融治疗方式结合,对肺部肿瘤进行消融治
疗。随着科技的不断完善,RAB的应用会越来越广泛,是未来支气管镜的发展趋势。
[关键词] 机器人支气管镜;肺外周病变;经支气管肺活检
[中图分类号] R562 [文献标志码] A [文章编号] 1007⁃4368(2025)05⁃699⁃08
doi:10.7655/NYDXBNSN250067
Application progress of robotic⁃assisted bronchoscopy
1
1,2
CHEN Shujuan ,FANG Shencun ,HOU Zhibo 1,2*
Department of Respiratory Medicine,the Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029;
1
2 Department of Endoscopy,Nanjing Chest Hospital,Nanjing 210029,China
[Abstract] With the widespread use of low⁃dose computed tomography,the detection rate of peripheral pulmonary lesions(PPLs)is
increasing year by year. Tissue biopsies of PPLs are required to obtain a pathological diagnosis. PPLs are far away from the central
airway and close to the pleura,making it difficult to reach with conventional bronchoscopy,resulting in suboptimal diagnostic rates and
sensitivity. Although percutaneous lung biopsy has improved diagnostic rates,it has a high rate of complications. Robotic⁃assisted
bronchoscopy(RAB)is a new technology for the diagnosis of lung lesions,improving navigation accuracy,expanding the reach of the
lens,and offering advantages of high accuracy,stability and flexibility,leading to higher diagnostic rate and safety compared to
traditional bronchoscopy. RAB can also serve as an interventional platform combined with the existing ablation therapy for tumor
ablation in the lungs. With continuous technological advancements,the application of RAB will become more widespread and
represents the future trend in bronchoscopy development.
[Key words] robotic⁃assisted bronchoscopy;peripheral pulmonary lesions;transbronchial lung biopsy
[J Nanjing Med Univ,2025,45(05):699⁃706]
随着胸部 CT 在晚期肺部疾病诊断中的应用增 断对具有高度恶性风险的 PPL 至关重要,同时可以
加以及肺癌筛查指南的放宽,肺外周病变(peripheral 避免对良性病变的过度治疗。然而影像学表现不
[1]
pulmonary lesion,PPL)的检出率逐年增加 ,经影像 足以精准区分良性和恶性病变,组织活检仍然是区
[2]
学检查发现的肺结节约95%为良性 。早发现早诊 分肺结节良恶性及制定合适治疗方案的金标准。
目前,PPL活检方法主要有CT引导下经皮肺穿刺活
检(percutaneous transthoracic needle biopsy,PTNB)、
[基金项目] 江苏省自然科学基金(BK20221184)
经支气管镜活检(transbronchial biopsy,TBB)和外科
∗
通信作者(Corresponding author),E⁃mail:zhibohou@njmu.edu.
cn(ORCID:0009⁃0009⁃1361⁃8532) 手术。PTNB 是当前诊断肺癌的重要手段,其灵敏

