Page 18 - 南京医科大学自然版

第45卷第5期
·604 · 南 京 医 科 大 学 学 报 2025年5月

2023，24（6）：925-940 trophil PAD4/NOX ⁃ dependent cerebrovasular throm⁃
［71］EL AMKI M，GLÜCK C，BINDER N，et al. Neutrophils boinflammation［J］. Int J Biol Sci，2023，19（3）：852-
obstructing brain capillaries are a major cause of no⁃re⁃ 864
flow in ischemic stroke［J］. Cell Rep，2020，33（2）： ［83］MU Q C，YAO K，SYEDA M Z，et al. Neutrophil targeting
108260 platform reduces neutrophil extracellular traps for im⁃
［72］SUN F Y，ZHOU J，CHEN X Y，et al. No⁃reflow after re⁃ proved traumatic brain injury and stroke theranostics［J］.
canalization in ischemic stroke：from pathomechanisms to Adv Sci，2024，11（21）：e2308719
therapeutic strategies［J］. J Cereb Blood Flow Metab， ［84］BARBHUYAN T，PATEL R B，BUDNIK I，et al. Genetic
2024，44（6）：857-880 ablation of myeloid integrin α9 attenuates early athero⁃
［73］NAMAZI M，MAHMOUDI E，SAFI M，et al. The No⁃re⁃ sclerosis［J］. J Leukoc Biol，2024，116（5）：1208-1214
flow phenomenon：Is it predictable by demographic fac⁃ ［85］WANG Y C，LU Y B，HUANG X L，et al. Myeloperoxi⁃
tors and routine laboratory data?［J］. Acta Biomed，2021， dase：A new target for the treatment of stroke?［J］. Neural
92（5）：e2021297 Regen Res，2022，17（8）：1711-1716
［74］GE L，ZHOU X，JI W J，et al. Neutrophil extracellular ［86］CAO J Y，ROTH S，ZHANG S J，et al. DNA⁃sensing in⁃
traps in ischemia⁃reperfusion injury⁃induced myocardial flammasomes cause recurrent atherosclerotic stroke［J］.
no⁃reflow：therapeutic potential of DNase⁃based reperfu⁃ Nature，2024，633（8029）：433-441
sion strategy［J］. Am J Physiol Heart Circ Physiol，2015， ［87］DHANESHA N，PATEL R B，DODDAPATTAR P，et al.
308（5）：H500-H509 PKM2 promotes neutrophil activation and cerebral throm⁃
［75］ERDENER Ş E，TANG J B，KILIÇ K，et al. Dynamic cap⁃ boinflammation：therapeutic implications for ischemic
illary stalls in reperfused ischemic penumbra contribute stroke［J］. Blood，2022，139（8）：1234-1245
to injury：a hyperacute role for neutrophils in persistent ［88］CLEMENTE⁃MORAGÓN A，OLIVER E，CALLE D，et al.
traffic jams［J］. J Cereb Blood Flow Metab，2021，41（2）： Neutrophil β1 adrenoceptor blockade blunts stroke⁃associ⁃
236-252 ated neuroinflammation［J］. Br J Pharmacol，2023，180
［76］LI Y S，XU J Y，YU T T，et al. A labeling strategy for the （4）：459-478
three⁃dimensional recognition and analysis of microvascu⁃ ［89］XIE M Z，HAO Y L，FENG L S，et al. Neutrophil hetero⁃
lar obstruction in ischemic stroke［J］. Theranostics，2023， geneity and its roles in the inflammatory network after
13（1）：403-416 ischemic stroke［J］. Curr Neuropharmacol，2023，21（3）：
［77］INVESTIGATORS E A S T. Use of anti⁃ICAM⁃1 therapy 621-650
in ischemic stroke：results of the enlimomab acute stroke ［90］ABDELNASEER M M，ELFAUOMY N M，ESMAIL E H，
trial［J］. Neurology，2001，57（8）：1428-1434 et al. Matrix metalloproteinase ⁃ 9 and recovery of acute
［78］KRAMS M，LEES K R，HACKE W，et al. Acute stroke ischemic stroke［J］. J Stroke Cerebrovasc Dis，2017，26
therapy by inhibition of neutrophils（ASTIN）：an adaptive （4）：733-740
dose⁃response study of UK⁃ 279，276 in acute ischemic ［91］WŁODARCZYK L，CICHON N，KARBOWNIK M S，et
stroke［J］. Stroke，2003，34（11）：2543-2548 al. Exploring the role of MMP⁃9 and MMP⁃9/TIMP⁃1 ratio
［79］CHAI G R，LIU S，YANG H W，et al. Quercetin protects in subacute stroke recovery：a prospective observational
against diabetic retinopathy in rats by inducing heme oxy⁃ study［J］. Int J Mol Sci，2024，25（11）：5745
genase⁃1 expression［J］. Neural Regen Res，2021，16（7）： ［92］SIRAKI A G. The many roles of myeloperoxidase：from in⁃
1344-1350 flammation and immunity to biomarkers，drug metabolism
［80］NÉMETH Z，DEMETER F，DOBÓ J，et al. Complement and drug discovery［J］. Redox Biol，2021，46：102109
MASP ⁃ 1 modifies endothelial wound healing［J］. Int J ［93］NELANDER K，LAGERSTROM⁃FERMER M，AMILON
Mol Sci，2024，25（7）：4048 C，et al. Early clinical experience with AZD4831，a novel
［81］SEKHERI M，OTHMAN A，FILEP J G. β2 integrin regu⁃ myeloperoxidase inhibitor，developed for patients with
lation of neutrophil functional plasticity and fate in the heart failure with preserved ejection fraction［J］. Clin
resolution of inflammation［J］. Front Immunol，2021，12： Transl Sci，2021，14（3）：812-819
660760 ［收稿日期］ 2024-11-13
［82］ANSARI J，VITAL S A，YADAV S，et al. Regulating neu⁃ （本文编辑：陈汐敏）