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associated pathologies[J]. Cell Mol Immunol,2015,12 geting neutrophil extracellular traps for stroke prognosis:
(1):5-23 a promising path[J]. Neurol Int,2023,15(4):1212-1226
[18]WINTERBOURN C C,KETTLE A J,HAMPTON M B. [33]FANG H J,BO Y F,HAO Z F,et al. A promising frontier:
Reactive oxygen species and neutrophil function[J]. Annu targeting NETs for stroke treatment breakthroughs[J].
Rev Biochem,2016,85:765-792 Cell Commun Signal,2024,22(1):238
[19]SADAF S,SINGH A K,AWASTHI D,et al. Augmentation [34]KANG L J,YU H L,YANG X,et al. Neutrophil extracel⁃
of iNOS expression in myeloid progenitor cells expedites lular traps released by neutrophils impair revasculariza⁃
neutrophil differentiation[J]. J Leukoc Biol,2019,106 tion and vascular remodeling after stroke[J]. Nat Com⁃
(2):397-412 mun,2020,11(1):2488
[20]CHEN S,CHEN H S,DU Q H,et al. Targeting myeloper⁃ [35]NABA A. Mechanisms of assembly and remodelling of the
oxidase(MPO)mediated oxidative stress and inflamma⁃ extracellular matrix[J]. Nat Rev Mol Cell Biol,2024,25
tion for reducing brain ischemia injury:potential applica⁃ (11):865-885
tion of natural compounds[J]. Front Physiol,2020,11:433 [36]HERNANDEZ S J,LIM R G,ONUR T,et al. An altered
[21]MOHAMUD Y A,HAGEMANN N,LUDEWIG P,et al. extracellular matrix⁃integrin interface contributes to Hun⁃
Roles of polymorphonuclear neutrophils in ischemic brain tington’s disease⁃associated CNS dysfunction in glial and
injury and post⁃ischemic brain remodeling[J]. Front Im⁃ vascular cells[J]. Hum Mol Genet,2023,32(9):1483-
munol,2021,12:825572 1496
[22]GARCIA⁃BONILLA L,SHAHANOOR Z,SCIORTINO R, [37]TABET A,APRA C,STRANAHAN A M,et al. Changes
et al. Analysis of brain and blood single ⁃ cell transcrip⁃ in brain neuroimmunology following injury and disease[J].
tomics in acute and subacute phases after experimental Front Integr Neurosci,2022,16:894500
stroke[J]. Nat Immunol,2024,25(2):357-370 [38]PIPERIGKOU Z,KYRIAKOPOULOU K,KOUTSAKIS C,
[23]CASSATELLA M A,ÖSTBERG N K,TAMASSIA N,et al. et al. Key matrix remodeling enzymes:functions and tar⁃
Biological roles of neutrophil ⁃ derived granule proteins geting in cancer[J]. Cancers,2021,13(6):1441
and cytokines[J]. Trends Immunol,2019,40(7):648-664 [39]MISHRA R R,NIELSEN B E,TRUDRUNG M A,et al.
[24]EASH K J,GREENBAUM A M,GOPALAN P K,et al. The effect of tissue inhibitor of metalloproteinases on scar
CXCR2 and CXCR4 antagonistically regulate neutrophil formation after spinal cord injury[J]. Cells,2024,13
trafficking from murine bone marrow[J]. J Clin Invest, (18):1547
2010,120(7):2423-2431 [40]GUO Y Z,DONG L D,GONG A,et al. Damage to the
[25]HERWALD H,EGESTEN A. On PAMPs and DAMPs[J]. blood ⁃ brain barrier and activation of neuroinflammation
J Innate Immun,2016,8(5):427-428 by focal cerebral ischemia under hyperglycemic condi⁃
[26]BALOG B M,SONTI A,ZIGMOND R E. Neutrophil biology tion[J]. Int J Mol Med,2021,48(1):142
in injuries and diseases of the central and peripheral ner⁃ [41]BEDDOWS C A,SHI F Y,HORTON A L,et al. Pathogenic
vous systems[J]. Prog Neurobiol,2023,228:102488 hypothalamic extracellular matrix promotes metabolic dis⁃
[27]PAPAYANNOPOULOS V. Neutrophil extracellular traps ease[J]. Nature,2024,633(8031):914-922
in immunity and disease[J]. Nat Rev Immunol,2018,18 [42]SUMMERS L, KANGWANTAS K, RODRIGUEZ ⁃
(2):134-147 GRANDE B,et al. Activation of brain endothelial cells by
[28]LI S,YING S N,WANG Y Q,et al. Neutrophil extracellu⁃ interleukin⁃1 is regulated by the extracellular matrix after
lar traps and neutrophilic dermatosis:an update review[J]. acute brain injury[J]. Mol Cell Neurosci,2013,57:93-
Cell Death Discov,2024,10(1):18 103
[29]JIMÉNEZ⁃ALCÁZAR M,KIM N,FUCHS T A. Circulat⁃ [43]VIRANI S S,ALONSO A,BENJAMIN E J,et al. Heart
ing extracellular DNA:Cause or consequence of thrombo⁃ disease and stroke statistics⁃ 2020 update:a report from
sis?[J]. Semin Thromb Hemost,2017,43(6):553-561 the American heart association[J]. Circulation,2020,141
[30]ZHAO Z Y,PAN Z R,ZHANG S,et al. Neutrophil extra⁃ (9):e139-e596
cellular traps:a novel target for the treatment of stroke[J]. [44]LIU Q,SHI K B,WANG Y J,et al. Neurovascular inflam⁃
Pharmacol Ther,2023,241:108328 mation and complications of thrombolysis therapy in
[31]DENORME F,PORTIER I,RUSTAD J L,et al. Neutro⁃ stroke[J]. Stroke,2023,54(10):2688-2697
phil extracellular traps regulate ischemic stroke brain in⁃ [45]XIE J L,PANG C Y,YU H,et al. Leukocyte indicators
jury[J]. J Clin Invest,2022,132(10):e154225 and variations predict worse outcomes after intravenous
[32]LIAPTSI E,MERKOURIS E,POLATIDOU E,et al. Tar⁃ thrombolysis in patients with acute ischemic stroke[J]. J

