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trophic factor signaling in depression and antidepressant PLoS One,2011,6(4):e17600
action[J]. Biol Psychiatry,2021,90(2):128-136 [67]WU M V,SHAMY J L,BEDI G,et al. Impact of social sta⁃
[56]HAN M,ZENG D Y,TAN W,et al. Brain region⁃specific tus and antidepressant treatment on neurogenesis in the
roles of brain⁃derived neurotrophic factor in social stress⁃ baboon hippocampus [J]. Neuropsychopharmacology,
induced depressive⁃like behavior[J]. Neural Regen Res, 2014,39(8):1861-1871
2025,20(1):159-173 [68]于秀军,李 奕,台立稳,等. 糖皮质激素对成体海马神
[57]彭 薇,贾志云,龚启勇. 难治性抑郁症神经影像研究 经祖细胞的影响[J]. 中国组织工程研究,2013,17
进展[J]. 生物医学工程学杂志,2018,35(5):794-798 (19):3521-3526
PENG W,JIA Z Y,GONG Q Y. Advances in neuroimag⁃ YU X J,LI Y,TAI L W,et al. Effects of glucocorticoids
ing research of treatment⁃resistant depression[J]. Journal on neural progenitor cells in adult hippocampus[J]. Jour⁃
of Biomedical Engineering,2018,35(5):794-798 nal of China Tissue Engineering,2013,17(19):3521-3526
[58]李 敏,毕洪生,翟 亮,等. 海马及其神经环路在抑郁 [69]SNYDER J S,SOUMIER A,BREWER M,et al. Adult hip⁃
症发生机制中的研究进展[J]. 神经疾病与精神卫生, pocampal neurogenesis buffers stress responses and de⁃
2024,24(12):890-895 pressive behaviour[J]. Nature,2011,476(7361):458-461
LI M,BI H S,ZHAI L,et al. Research progress of hippo⁃ [70]SCHLOESSER R J,MANJI H K,MARTINOWICH K.
campus and its neural circuits in the pathogenesis of de⁃ Suppression of adult neurogenesis leads to an increased
pression[J]. Neurological Disorders And Mental Health, hypothalamo⁃pituitary⁃adrenal axis response[J]. Neurore⁃
2024,24(12):890-895 port,2009,20(6):553-557
[59]靳宇倡,丁美月. 产后抑郁的预测因素及神经生理 [71]CHEN H S,WANG F,CHEN J G. Epigenetic mecha⁃
机制[J]. 心理科学进展,2017,25(7):1145-1161 nisms in depression:implications for pathogenesis and
JIN Y C,DING M Y. Predictors and neurophysiological treatment[J]. Curr Opin Neurobiol,2024,85:102854
mechanisms of postpartum depression[J]. Advances in [72]SANTARELLI L,SAXE M,GROSS C,et al. Requirement
Psychological Science,2017,25(7):1145-1161 of hippocampal neurogenesis for the behavioral effects of
[60]ANTONIUK S,BIJATA M,PONIMASKIN E,et al. Chron⁃ antidepressants[J]. Science,2003,301(5634):805-809
ic unpredictable mild stress for modeling depression in ro⁃ [73]鄂 晓,张英鸽. 成年海马中神经发生及影响因素[J].
dents:meta ⁃ analysis of model reliability[J]. Neurosci 生物技术通讯,2010,21(3):443-448
Biobehav Rev,2019,99:101-116 E X,ZHANG Y G. Neurogenesis and its influencing fac⁃
[61]孙美芳. 抑郁模型大鼠海马糖皮质激素受体及海马形 tors in adult hippocampus[J]. Biotechnology Bulletin,
态的动态研究[D]. 镇江:江苏大学,2016 2010,21(3):443-448
SUN M F. Dynamic study of hippocampal glucocorticoid [74]BOLDRINI M,UNDERWOOD M D,HEN R,et al. Anti⁃
receptor and hippocampal morphology in depressed depressants increase neural progenitor cells in the human
rats[D]. Zhenjiang:Jiangsu University,2016 hippocampus[J]. Neuropsychopharmacology,2009,34
[62]HUANG Y L,ZENG N X,CHEN J,et al. Dynamic chang⁃ (11):2376-2389
es of behaviors,dentate gyrus neurogenesis and hippocam⁃ [75]REIF A,FRITZEN S,FINGER M,et al. Neural stem cell
pal miR⁃124 expression in rats with depression induced proliferation is decreased in schizophrenia,but not in de⁃
by chronic unpredictable mild stress[J]. Neural Regen pression[J]. Mol Psychiatry,2006,11(5):514-522
Res,2020,15(6):1150-1159 [76]WANG J W,DAVID D J,MONCKTON J E,et al. Chronic
[63]SURGET A,TANTI A,LEONARDO E D,et al. Antide⁃ fluoxetine stimulates maturation and synaptic plasticity of
pressants recruit new neurons to improve stress response adult ⁃ born hippocampal granule cells[J]. J Neurosci,
regulation[J]. Mol Psychiatry,2011,16(12):1177-1188 2008,28(6):1374-1384
[64]GOLDEN S A,COVINGTON H E,BERTON O,et al. A [77]DAVID D J,WANG J W,SAMUELS B A,et al. Implica⁃
standardized protocol for repeated social defeat stress in tions of the functional integration of adult⁃born hippocam⁃
mice[J]. Nat Protoc,2011,6(8):1183-1191 pal neurons in anxiety⁃depression disorders[J]. Neurosci⁃
[65]REVEST J M,DUPRET D,KOEHL M,et al. Adult hippo⁃ entist,2010,16(5):578-591
campal neurogenesis is involved in anxiety⁃related behav⁃ [78]CHEN R W,CHUANG D M. Long term lithium treatment
iors[J]. Mol Psychiatry,2009,14(10):959-967 suppresses p53 and Bax expression but increases Bcl⁃ 2
[66]PERERA T D,DWORK A J,KEEGAN K A,et al. Neces⁃ expression. A prominent role in neuroprotection against
sity of hippocampal neurogenesis for the therapeutic ac⁃ excitotoxicity[J]. J Biol Chem,1999,274(10):6039-
tion of antidepressants in adult nonhuman primates[J]. 6042

