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［9］ CHEN D，LIN X，ZHANG C，et al. Activated Wnt signal⁃ 1601-1607
ing promotes growth and progression of AFP ⁃ producing ［21］王晓辉，张 威，郭玉霖，等. 甲胎蛋白升高型胃癌的临
gastric cancer in preclinical models［J］. Cancer Manag 床病理特征及预后分析［J］. 中国医刊，2023，58（1）：
Res，2019，11：1349-1362 63-66
［10］HU X，CHEN R，WEI Q，et al. The landscape of alpha fe⁃ WANG X H，ZHANG W，GUO Y L，et al. Clinicopatholog⁃
toprotein in hepatocellular carcinoma：where are we?［J］. ical features and prognostic analysis of alpha⁃fetoprotein⁃
Int J Biol Sci，2022，18（2）：536-551 producing gastric cancer［J］. Chinese Journal of Medi⁃
［11］FUJIMOTO M，MATSUZAKI I，NISHINO M，et al. HER2 cine，2023，58（1）：63-66
is frequently overexpressed in hepatoid adenocarcinoma ［22］MAO X，WANG J，LUO F. Alpha⁃fetoprotein can promote
and gastric carcinoma with enteroblastic differentiation：a gastric cancer progression via upregulation of metastasis⁃
comparison of 35 cases to 334 gastric carcinomas of other associated colon cancer 1［J］. Oncol Lett，2022，23（3）：
histological types［J］. J Clin Pathol，2018，71（7）：600- 84
607 ［23］ZHAN Z，CHEN B，YU J，et al. Elevated serum alpha⁃fe⁃
［12］LU J，DING Y，CHEN Y，et al. Whole⁃exome sequencing toprotein is a significant prognostic factor for patients
of alpha⁃fetoprotein producing gastric carcinoma reveals with gastric cancer：results based on a large⁃scale retro⁃
genomic profile and therapeutic targets［J］. Nat Commun， spective study［J］. Front Oncol，2022，12：901061
2021，12：3946 ［24］WANG R，LI J，XU D，et al. Dynamic change in serum al⁃
［13］KAMEI S，KONO K，AMEMIYA H，et al. Evaluation of pha ⁃ fetoprotein level predicts treatment response and
VEGF and VEGF⁃C expression in gastric cancer cells pro⁃ prognosis of alpha⁃fetoprotein⁃producing gastric cancer
ducing α⁃fetoprotein［J］. J Gastroenterol，2003，38（6）： ［J］. Medicine，2020，99（47）：e23326
540-547 ［25］TAKAYAMA⁃ISAGAWA Y，KANETAKA K，KOBAYAS⁃
［14］KONG X X，LI X L，TIAN Y，et al. The clinicopathologi⁃ HI S，et al. High serum alpha⁃fetoprotein and positive im⁃
cal characteristics of alpha⁃fetoprotein⁃producing adeno⁃ munohistochemistry of alpha ⁃ fetoprotein are related to
carcinoma of the gastrointestinal tract⁃a single⁃center ret⁃ poor prognosis of gastric cancer with liver metastasis［J］.
rospective study［J］. Front Oncol，2021，11：635537 Sci Rep，2024，14（1）：3695
［15］WENG W，ZHANG M，NI S，et al. Decreased expression ［26］VATANSEVER S，ÖZER M K，ERDOGAN E I. Prognostic
of claudin ⁃ 18.2 in alpha ⁃ fetoprotein ⁃ producing gastric significance of α⁃fetoprotein in gastric adenocarcinoma［J］.
cancer compared to conventional gastric cancer［J］. J Gas⁃ Prz Gastroenterol，2022，17（1）：35-40
trointest Oncol，2022，13（3）：1035-1045 ［27］ZHANG F. Recurrent metastatic patterns and prognosis af⁃
［16］WANG Y K，SHEN L，JIAO X，et al. Predictive and prog⁃ ter radical surgery in patients with alpha⁃fetoprotein⁃pro⁃
nostic value of serum AFP level and its dynamic changes ducing gastric cancer：a retrospective cohort study［J］.
in advanced gastric cancer patients with elevated serum Am J Cancer Res，2024，14（5）：2124-2140
AFP［J］. World J Gastroenterol，2018，24（2）：266-273 ［28］TONG Y，ZHAO Y，SHAN Z，et al. CA724 predicts over⁃
［17］HE R，YANG Q，DONG X，et al. Clinicopathologic and all survival in locally advanced gastric cancer patients
prognostic characteristics of alpha⁃fetoprotein⁃producing with neoadjuvant chemotherapy［J］. BMC Cancer，2021，
gastric cancer［J］. Oncotarget，2017，8（14）：23817- 21：4
23830 ［29］JIN C，HU J，BALAPATTABI K，et al. Case report：a rare
［18］BOZKAYA Y，DEMIRCI N S，KURTIPEK A，et al. Clini⁃ occurrence of triple malignancy of the stomach，rectum
copathological and prognostic characteristics in patients and liver in a single patient［J］. Front Oncol，2022，12：
with AFP⁃secreting gastric carcinoma［J］. Mol Clin On⁃ 945689
col，2017，7（2）：267-274 ［30］ABE D，AKAZAWA Y，YATAGAI N，et al. Clinicopatho⁃
［19］OTA T，SAKASHITA K，SAWADA R，et al. Long⁃term logical characteristics of gastric adenocarcinoma with en⁃
survival with nivolumab followed by irinotecan after total teroblastic differentiation and gastric adenocarcinoma
gastrectomy in alpha ⁃ fetoprotein ⁃ producing gastric can⁃ with enteroblastic marker expression［J］. Virchows Ar⁃
cer：a case report and review of the literature［J］. Surg chiv，2023，483（3）：405-414
Case Rep，2023，9（1）：71 ［31］LLI M，MEI Y X，WEN J H，et al. Hepatoid adenocarcino⁃
［20］HORI S，HONDA M，KOBAYASHI H，et al. A grading ma⁃clinicopathological features and molecular characteris⁃
system for predicting the prognosis of gastric cancer with tics［J］. Cancer Lett，2023，559：216104
liver metastasis［J］. Jpn J Clin Oncol，2021，51（11）： ［32］USHIKU T，SHINOZAKI A，SHIBAHARA J，et al. SALL4