Page 114 - 南京医科大学自然版
P. 114

第46卷第5期
              ·736 ·                             南 京    医 科 大 学 学         报                        2026年5月


             [22]BOUSHEY C J,BERESFORD S A,OMENN G S,et al.          mice[J]. Am J Cardiovasc Dis,2017,7(2):33-47
                   Lowering blood homocysteine with folic acid based sup⁃  [35]DONG W B,ZHOU M Y,DONG M,et al. Keto acid me⁃
                   plements:meta ⁃ analysis of randomised trials[J]. BMJ,  tabolites of branched⁃chain amino acids inhibit oxidative
                   1998,316(7135):894-898                            stress⁃induced necrosis and attenuate myocardial ischemia⁃
             [23]孔    娟. 高同型半胱氨酸血症诊疗专家共识[J]. 肿瘤                      reperfusion injury[J]. J Mol Cell Cardiol,2016,101:90-
                   代谢与营养电子杂志,2020,7(3):283-288                       98
                   KONG J. Expert consensus on diagnosis and treatment of  [36]NEWGARD C B. Interplay between lipids and branched⁃
                   hyperhomocysteinemia[J]. Electronic Journal of Tumor  chain amino acids in development of insulin resistance[J].
                   Metabolism and Nutrition,2020,7(3):283-288        Cell Metab,2012,15(5):606-614
             [24]WU X Y,HAN Z Y,LIU B N,et al. Gut microbiota con⁃  [37]ALQUDAH A,QNAIS E,WEDYAN M,et al. Amino acid
                   tributes to the methionine metabolism in host[J]. Front  profiles:exploring their diagnostic and pathophysiological
                   Microbiol,2022,13:1065668                         significance in hypertension[J]. Mol Biol Rep,2024,51
             [25]SELHUB J,TROEN A M. Sulfur amino acids and athero⁃  (1):200
                   sclerosis:a role for excess dietary methionine[J]. Ann N  [38]CZIBIK G,MEZDARI Z,MURAT ALTINTAS D,et al.
                   Y Acad Sci,2016,1363:18-25                        Dysregulated phenylalanine catabolism plays a key role
             [26]BLACHIER F,ANDRIAMIHAJA M,BLAIS A. Sulfur ⁃         in the trajectory of cardiac aging[J]. Circulation,2021,
                   containing amino acids and lipid metabolism[J]. J Nutr,  144(7):559-574
                   2020,150(Suppl 1):2524-2531                  [39]JAUHIAINEN R,VANGIPURAPU J,LAAKSO A,et al.
             [27]GREEN C R,WALLACE M,DIVAKARUNI A S,et al.           The association of 9 amino acids with cardiovascular
                   Branched ⁃ chain amino acid catabolism fuels adipocyte  events in Finnish men in a 12⁃year follow⁃up study[J]. J
                   differentiation and lipogenesis[J]. Nat Chem Biol,2016,  Clin Endocrinol Metab,2021,106(12):3448-3454
                   12(1):15-21                                  [40]周曼丽,钱舒乐,胡伊蕾,等. 冠心病心血瘀阻证大鼠心
             [28]NILSSON M,HOLST J J,BJÖRCK I M. Metabolic effects   肌代谢组学研究[J]. 中医杂志,2022,63(10):968-975
                   of amino acid mixtures and whey protein in healthy sub⁃  ZHOU M L,QIAN S L,HU Y L,et al. Study on myocardi⁃
                   jects:studies using glucose⁃equivalent drinks[J]. Am J  al metabolomics of rats with coronary heart disease of
                   Clin Nutr,2007,85(4):996-1004                     blood stasis syndrome in traditional Chinese medicine[J].
             [29]NEWGARD C B,AN J,BAIN J R,et al. A branched ⁃       Journal of Traditional Chinese Medicine,2022,63(10):
                   chain amino acid⁃related metabolic signature that differ⁃  968-975
                   entiates obese and lean humans and contributes to insulin  [41]SUDAR ⁃ MILOVANOVIC E,GLUVIC Z,OBRADOVIC
                   resistance[J]. Cell Metab,2009,9(4):311-326       M,et al. Tryptophan metabolism in atherosclerosis and dia⁃
             [30]CUMMINGS N E,WILLIAMS E M,KASZA I,et al. Res⁃       betes[J]. Curr Med Chem,2022,29(1):99-113
                   toration of metabolic health by decreased consumption of  [42]OH C M,PARK S,KIM H. Serotonin as a new therapeutic
                   branched⁃chain amino acids[J]. J Physiol,2018,596(4):  target for diabetes mellitus and obesity[J]. Diabetes
                   623-645                                           Metab J,2016,40(2):89-98
             [31]MAHENDRAN Y,JONSSON A,HAVE C T,et al. Genetic  [43]NEINAST M,MURASHIGE D,ARANY Z. Branched
                   evidence of a causal effect of insulin resistance on  chain amino acids[J]. Annu Rev Physiol,2019,81:139-164
                   branched ⁃ chain amino acid levels[J]. Diabetologia,  [44]FU X M,LU H W,GAO M,et al. Nitric oxide in the cardio⁃
                   2017,60(5):873-878                                cerebrovascular system:source,regulation and applica⁃
             [32]WANG Q ,HOLMES M V ,DAVEY SMITH G ,et al.           tion[J]. Nitric Oxide,2024,152:48-57
                   Genetic support for a causal role of insulin resistance on  [45]MORRIS S M Jr. Enzymes of arginine metabolism[J]. J
                   circulating branched ⁃ chain amino acids and inflamma⁃  Nutr,2004,134(10 Suppl):2743-2747
                   tion[J]. Diabetes Care,2017,40(12):1779-1786  [46]WARD M E,TOPORSIAN M,SCOTT J A,et al. Hypoxia
             [33]MAHBUB M H,YAMAGUCHI N,HASE R,et al. Plasma         induces a functionally significant and translationally effi⁃
                   branched ⁃ chain and aromatic amino acids in relation to  cient neuronal NO synthase mRNA variant[J]. J Clin In⁃
                   hypertension[J]. Nutrients,2020,12(12):3791       vest,2005,115(11):3128-3139
             [34]BRUCKBAUER A,BANERJEE J,CAO Q,et al. Leucine⁃  [47]HONG F F,LIANG X Y,LIU W,et al. Roles of ENOS in
                   nicotinic acid synergy stimulates AMPK/Sirt1 signaling  atherosclerosis treatment[J]. Inflamm Res,2019,68(6):
                   and regulates lipid metabolism and lifespan in Caenorhab⁃  429-441
                   ditis elegans,and hyperlipidemia and atherosclerosis in  [48]ADAMS S,CHE D S,QIN G X,et al. Novel biosynthesis,
   109   110   111   112   113   114   115   116   117   118   119