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第46卷第8期
               ·1238 ·                           南 京    医 科 大 学 学         报                        2026年8月


                                     with  with                    me⁃                         PQR
                   and               correlated  correlated              glycosylation  function  increased  biomarker  peritoneal  patients
                   Function  significance  -  -  -  -  -  -  -  -  inflammatory  immune  -  -  -     -  -  in  PE

                                     Positively  FDR  Positively  FDR  ⁃  Pro  tabolite  Altered  and  of  Part  diagnostic  Elevated  of  fluid



                              [30]                     [42]    [25]
                   Other  samples  -  (Feces )  -  -  -  -  -  (EF)  -  ↑ (Cumulus  CC)  cell,  -  -  -  -  -  -  -  -  -

                               ↓                       ↓
                                                                              [11]
                   Tissue  sample  -  -  -  -  -  -  -  [26]  ↑  -  -  -  -    (Ⅳ)    -     -  -     -  -  -

                                                                               ↑
                    Urine  -   -  -  -     -     -   -  -  -  -    -     -     -      -     -  -     -  -  -

                   Peritoneal  fluid  -  -  -  -  -  -  -  -  -  -  -    -     -      -     -  -     -  -  -




                   Endometrial  fluid  -  -  -  -  -  -  -  -  -  -  -   -     -      -     -  -     -  -  -




                                                 [50]  Ⅳ)                      (Ⅰ-             (Ⅲ,
                   Follicular  fluid  -  [9]  ↑  [9]  ↑  [38]  ↓  [38]  ↓  (Ⅲ,  ↓  [23]  ↑  -  [23]  ↑  -  -  -  [9]  ↓  ,  ↓  [18]  Ⅳ)  [23]  ↑  [21]  ↑  [23]  ↓  ,  ↑  [50]  Ⅳ)  ⁃  [23]  ↑  [23]  ↑




                    Plasma  ↓ (Ⅰ-  [10]  Ⅳ)  -  -  -  -  -  -  -  -  -  [36]  ↑  (Ⅰ-  ↑  [10]  Ⅳ)  -  -  -  -  -  -  -


                                                                                              [16 17 ,  [32]  [16]

                    Serum  -   -  -  -     -     -   -  -  -  -    -     -     -      -     -  (Ⅰ-Ⅳ) , ]  (Ⅳ)  (Ⅰ-Ⅳ)  -  -


                                                                                               ↓  ↑  ↓
                         derivatives                                                  metabo⁃

                    Category  acid                        Amino acid metabolites  acids  acids  acids  acids


                         Amino  Nucleobases  Nucleosides  Carbohydrates  Carbohydrates  Hormones  Nucleosides  Lipids  Fatty  Fatty  Carbohydrates  Carbohydrates  Carbohydrate  lites  Sphingolipids  Amino  Amino  Dipeptides  Dipeptides






                    Metabolite       acid        Dehydroepiandrosterone  acid  acid   Glucose⁃1⁃phosphate  acid  arginine  phenylalanine



                (续表1)    Creatinine  Cytosine  Cytodine  D⁃galacturonic  D⁃mannosamine  Deoxyuridine  Diacylglycerols  Dihydroindole  Docosahexaenoic  Eicosatrienoic  Fucose  Glucose  Glucosylceramide  Glutamine  Glutamic  Glutamyl  Glutamyl
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