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第46卷第8期
               ·1242 ·                           南 京    医 科 大 学 学         报                        2026年8月


                         biomark⁃  endome⁃  antioxidant  intestinal  marker  oxi⁃  C  cel⁃  regulation  unsatu⁃  in  OE  of  me⁃  ab⁃  early
                   and                                  stress  vitamin  abnormal  altered  fluid  metabolism  in
                   Function  significance  as  ovarian  -  to  and  function  -  -  -  -  osmotic  and  forms  -  Anti ⁃ inflammatory  -  -  -
                         Identified  for  ers  triosis  Related  capacity  barrier  Oxidative  reflecting  dation  Reflects  lular  ,Saturated  rated  endometrial  tabolite  Purine  normality  phase




                         ↑  ,  [40]  ,  [42]  cells,  [25]  [30]             [40]  [42]
                   Other  samples  [25]  (CC)  (DMBS)  (EF)  ↓ (Mural  MGC)  (Feces )  -  -  -  -  -  -  (DMBS)  (EF)  -  -  -  -  -  -

                         ↓    ↓     granulosa  ↓                             ↑  ↓    [ 39        [ 39     [ 39

                   Tissue  sample  [26]  ↑  [29]  ↑  (Ⅲ,  ↑  [11]  Ⅳ)  -  -  -  -  -  -  [26]  ↑  Ⅱ) ]  (Ⅰ,  ↑  -  -  Ⅱ) ]  (Ⅰ,  ↓  Ⅱ) ]  (Ⅰ,  ↑  [29]  ↑



                    Urine  -     -        -        -  -  -       -  -  -     -        -  -     -  -        -  -

                   Peritoneal  fluid  -  -  -     [28 (Ⅰ-Ⅳ) ]  ↑  [28 (Ⅰ-Ⅳ) ]  ↑  -  -  -  -  -  -  -  -  -  -  -




                   Endometrial  fluid  -  -  -     -  -  -       -  -  -     -        -  -     -  -        -  -




                                                                                     [50]  Ⅳ)  ,(Ⅲ,
                   Follicular  fluid  -  -  -      -  -  -      [23]  ↑  [23]  ↑  -  -  (Ⅲ,  ↑  [9, 23]  ↑  ↑  [50]  Ⅳ)  [9]  ↑  -  -  [9, 23]  ↑




                    Plasma  (Ⅲ,  ↑  [51]  Ⅳ)  -  -  [35]  (Ⅲ)  ↑  -  -  -  -  [35]  (Ⅲ)  ↑  -  -  ,  ↓ [36]  [15]  ↑  -  -  -  [36]  ↑



                                                                                     [16]
                                                        [31]                            [32]
                    Serum  -     -        -        -  -  (Ⅳ)     -  -  -     -        (Ⅰ-Ⅳ)  ↓ (Ⅳ)  -  -   -  -
                                                        ↑
                                                                                      ↓

                                          derivatives                                             metabolites

                    Category                       metabolites  acids  Amino acid metabolites  acids  acids
                         Sphingolipids  Sphingolipids  acid  Amino  Lipid  acids  Fatty  Organic  Nucleosides  Nucleobases  Lipids  Amino  Amino  Nucleobases  Nucleobase  Nucleosides  Nucleobases









                    Metabolite                     Tetradecenoylcarnitine  acid Tetracosahexaenoic  acid  Trimethylamine⁃N⁃oxide



                (续表1)    Sphingomyelins  Sphingosine  Taurine  Threonic  Thymidine  Thymine  Triacylglycerols  Tyrosine  Tryptophan  Uracil  acid  Uric  Xanthosine  Xanthine
   131   132   133   134   135   136   137   138   139   140   141