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第42卷第5期                张科明,胡行前,吴益斌,等. 术前PLR和NLR预测重度胆囊炎的效用[J].
                  2022年5月                     南京医科大学学报(自然科学版),2022,42(05):719-723                       ·723 ·


                性试验验证研究结果。此外,当根据NLR临界值划                                Surg,2021,45(3):754-764
                分患者人群时,患者分布不均衡,NLR≥3.0 组包括                       [7] PROCTOR M J,MORRISON D S,TALWAR D,et al. A
                更多年龄较大的患者和男性患者。因此,年龄和性                                 comparison of inflammation⁃based prognostic scores in pa⁃
                别可能作为混杂因素,影响NLR临界值与胆囊炎的                                tients with cancer. a glasgow inflammation outcome study
                                                                      [J]. Eur J Cancer,2011,47(17):2633-2641
                严重程度独立相关的结论。因此,对于本文得出的
                                                                 [8] DUŠAN M,SANJA S,NEBOJŠA L,et al. Prognostic val⁃
                结果,应考虑患者群体组成的差异。
                                                                       ue of preoperative neutrophil⁃to⁃lymphocyte ratio for pre⁃
                    综上可知,胆囊炎患者的常规术前PLR 和术前                             diction of severe cholecystitis[J]. J Med Biochem,2018,
                NLR 值不仅提供了识别重度胆囊炎患者的简单方
                                                                       37(2):121-127
                法,而且术前NLR还可作为预测住院时间延长的替                          [9] CHAO H D,ZHANG M W,SI Y C. Neutrophil to lympho⁃
                代指标。根据入院时的PLR和NLR值,我们发现胆                               cyte ratio predict mortality and major adverse cardiac
                囊炎患者可分为重度胆囊炎低风险(PLR<129.0 或                            events in acute coronary syndrome:a systematic review
                NLR <3.0)和 重 度 胆 囊 炎 高 风 险(PLR≥129.0 或                 and meta⁃analysis[J]. Clin Biochem,2018,52:131-136
                NLR≥3.0)。这种基于术前 PLR 和术前 NLR 值确定                  [10] GORDON C G,MATTA K,JAYARAM S,et al. C⁃reac⁃
                手术优先级的方法有望成为明确重度胆囊炎的替                                  tive protein is an independent predictor of difficult emer⁃
                                                                       gency cholecystectomy[J]. Cureus,2019,11(4):e4573
                代指标,并协助完善围手术期管理。
                                                                 [11] DAVIS B,CASTANEDA G,LOPEZ J. Subtotal cholecys⁃
               [参考文献]                                                  tectomy versus total cholecystectomy in complicated cho⁃
               [1] ANDREI M B,NEVILLE A,MICHAEL B,et al. Evalua⁃       lecystitis[J]. Am Surg,2012,78(7):814-817
                    tion of neutrophil⁃to⁃lymphocyte ratio as a potential bio⁃  [12] WEI C C,YU X S,EN H W,et al. CT findings for detect⁃
                    marker for acute cholecystitis[J]. J Surg Res,2017,209:  ing the presence of gangrenous ischemia in cholecystitis
                                                                      [J]. AJR Am J Roentgenol,2016,207(2):302-309
                    93-101
               [2] JOSS R W,JULIET M L,DAVID O,et al. Comparing the  [13] MOTOMURA T,SHIRABE K,MANO Y,et al. Neutro⁃
                    diagnostic accuracy of ultrasound and CT in evaluating  phillymphocyte ratio reflects hepatocellular carcinoma re⁃
                                                                       currence after liver transplantation via inflammatory mi⁃
                    acute cholecystitis[J]. AJR Am J Roentgenol,2018,211
                    (2):W92-W97                                        croenvironment[J]. J Hepatol,2013,58(1):58-64
               [3] VESELIN S,MIROSLAV M,NIKOLA K,et al. A prospec⁃  [14] KOICHI I. Predictive factors for a long postoperative stay
                    tive cohort study for prediction of difficult laparoscopic  after emergency laparoscopic cholecystectomy using the
                    cholecystectomy[J]. Ann Med Surg(Lond),2020,60:    2013 tokyo guidelines:a retrospective study[J]. Minim
                    728-733                                            Invasive Surg,2019,2019:3942584
               [4] DAVID W DA C,NICOLIEN J S,STEFAN A B,et al. Col⁃  [15] DAVID W,NIKLAS J,JONAS Z,et al. Transferring clini⁃
                    icky pain and related complications after cholecystectomy  cally established immune inflammation markers into exer⁃
                    for mild gallstone pancreatitis[J]. HPB(Oxford),2018,  cise physiology:focus on neutrophil⁃to⁃lymphocyte ratio,
                    20(8):745-751                                      platelet⁃to⁃lymphocyte ratio and systemic immune⁃inflam⁃
                    ·
               [5] IBRAHIM M,ÇILEM B D,ŞERIFE B,et al. Correction      mation index[J]. Eur J Appl Physiol,2021,121(7):
                    to:does the preoperative platelet⁃tolymphocyte ratio and  1803-1814
                    neutrophil⁃tolymphocyte ratio predict morbidity after gas⁃  [16] SIMPSON G,SAUNDERS R,WILSON J,et al. The role
                                                                       of the neutrophil:lymphocyte ratio(NLR)and th e CRP:
                    trectomy for gastric cancer?[J]. Mil Med Res,2020,7
                    (1):12                                             albumin ratio(CAR)in predicting mortality following
               [6] MECHTELD C DE J,RADU M,SHAHAB K. Neutrophil⁃        emergency laparotomy in the over 80 age group[J]. Eur J
                    to⁃lymphocyte ratio(NLR)and platelet⁃to⁃lymphocyte ratio  Trauma Emerg Surg,2018,44(6):877-882
                    (PLR)as possible prognostic markers for patients under⁃                 [收稿日期] 2021-11-27
                                                                                                (本文编辑:唐      震)
                    going resection of adrenocortical carcinoma[J]. World J
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