Page 145 - 南京医科大学学报自然科学版
P. 145
第43卷第7期 张天怡,苏 芃,梁景岩,等. 齐墩果酸对缺血性卒中的神经保护作用及机制研究进展[J].
2023年7月 南京医科大学学报(自然科学版),2023,43(07):1027-1031 ·1031 ·
[7] MIOC M,MILAN A,MALITA D,et al. Recent advances cell death in ischemic stroke and their therapeutic impli⁃
regarding the molecular mechanisms of triterpenic acids: cations[J]. Med Res Rev,2022,42(1):259-305
a review[J]. Int J Mol Sci,2022,23(14):7740 [19] COULTRAP S J,VEST R S,ASHPOLE N M,et al. CaM⁃
[8] GUDOITYTE E,ARANDARCIKAITE O,MAZEIKIENE KII in cerebral ischemia[J]. Acta Pharmacol Sin,2011,
I,et al. Ursolic and oleanolic acids:plant metabolites 32(7):861-872
with neuroprotective potential[J]. Int J Mol Sci,2021,22 [20] HOU Y,QIENI X,LI N,et al. Longzhibu disease and its
(9):4599 therapeutic effects by traditional Tibetan medicine:Ershi⁃
[9] NAKATSUCHI A,INAGAKI M,SUGIYAMA M,et al. As⁃ wei Chenxiang pills[J]. J Ethnopharmacol,2020,249:
sociation of salmonella serotypes with quinolone resis⁃ 112426
tance in broilers[J]. Food Saf,2018,6(4):156-159 [21] 郑霞薇,黄丽丽,谢国民. 齐墩果酸对脑缺血再灌注大
[10] QIN C,YANG S,CHU Y H,et al. Signaling pathways in⁃ 鼠的神经保护作用及机制研究[J]. 现代实用医学,
volved in ischemic stroke:molecular mechanisms and 2021,33(12):1551-1553
therapeutic interventions[J]. Signal Transduct Target [22] ZHANG Q,JIA M,WANG Y,et al. Cell death mecha⁃
Ther,2022,7(1):215 nisms in cerebral ischemia⁃reperfusion injury[J]. Neuro⁃
[11] CHO S O,BAN J Y,KIM J Y,et al. Anti⁃ischemic activi⁃ chem Res,2022,47(12):3525-3542
ties of aralia cordata and its active component,oleanolic [23] MAO R,ZONG N,HU Y,et al. Neuronal death mecha⁃
acid[J]. Arch Pharm Res,2009,32(6):923-932 nisms and therapeutic strategy in ischemic stroke[J].
[12] RONG Z T,GONG X J,SUN H B,et al. Protective effects Neurosci Bull,2022,38(10):1229-1247
of oleanolic acid on cerebral ischemic damage in vivo and [24] DATTA A,SARMAH D,MOUNICA L,et al. Cell death
H2O2 ⁃ induced injury in vitro[J]. Pharm Biol,2011,49 pathways in ischemic stroke and targeted pharmacothera⁃
(1):78-85 py[J]. Transl Stroke Res,2020,11(6):1185-1202
[13] ZHANG F,WANG S,ZHANG M,et al. Pharmacological [25] CAI S C,LI XP,LI X,et al. Oleanolic acid inhibits neuro⁃
induction of heme oxygenase⁃1 by a triterpenoid protects nal pyroptosis in ischaemic stroke by inhibiting miR⁃186⁃
neurons against ischemic injury[J]. Stroke,2012,43(5): 5p expression[J]. Exp Neurobiol,2021,30(6):401-414
1390-1397 [26] QIN C,ZHOU L Q,MA X T,et al. Dual functions of mi⁃
[14] VAN KANEGAN M J,DUNN D E,KALTENBACH L S, croglia in ischemic stroke[J]. Neurosci Bull,2019,35
et al. Dual activities of the anti⁃cancer drug candidate PBI⁃ (5):921-933
05204 provide neuroprotection in brain slice models for [27] CHOUDHURY G R,DING S. Reactive astrocytes and
neurodegenerative diseases and stroke[J]. Sci Rep,2016, therapeutic potential in focal ischemic stroke[J]. Neurobi⁃
6:25626 ol Dis,2016,85:234-244
[15] SHI Y J,SUN L L,JI X,et al. Neuroprotective effects of [28] MA Y,WANG J,WANG Y,et al. The biphasic function of
oleanolic acid against cerebral ischemia⁃reperfusion inju⁃ microglia in ischemic stroke[J]. Prog Neurobiol,2017,
ry in mice[J]. Exp Neurol,2021,343:113785 157:247-272
[16] SAPKOTA A,CHOI J W. Oleanolic acid provides neuro⁃ [29] CALTANA L,NIETO M L,BRUSCO A. Oleanolic acid:a
protection against ischemic stroke through the inhibition promising neuroprotective agent for cerebral ischemia[J].
of microglial activation and NLRP3 inflammasome activa⁃ Neural Regen Res,2015,10(4):540-541
tion[J]. Biomol Ther,2022,30(1):55-63 [30] CALTANA L,RUTOLO D,NIETO M L,et al. Further evi⁃
[17] LIN K,ZHANG Z,ZHANG Z,et al. Oleanolic acid allevi⁃ dence for the neuroprotective role of oleanolic acid in a
ates cerebral ischemia/reperfusion injury via regulation of model of focal brain hypoxia in rats[J]. Neurochem Int,
the GSK ⁃ 3β/HO ⁃ 1 signaling pathway[J]. Pharmaceuti⁃ 2014,79:79-87
cals,2021,15(1):1 [收稿日期] 2023-03-27
[18] TUO Q Z,ZHANG S T,LEI P. Mechanisms of neuronal (本文编辑:唐 震)