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第44卷第11期 王彦涵，张 莱，王 君，等. 心房颤动伴中度及以上心房功能性二尖瓣反流患者的临床特征［J］.
2024年11月 南京医科大学学报（自然科学版），2024，44（11）：1558-1564 ·1563 ·

表3 多因素Logistic回归分析
Table 3 Multivariate logistic regression analysis

Variable OR 95%CI P
Age 0.975 0.921-1.033 0.397
CHA2DS2⁃VASc score 1.111 0.888-1.389 0.358
Renal insufficiency 2.250 0.908-5.575 0.080
Persistent atrial fibrillation 0.835 0.303-2.299 0.726
NOAC 0.386 0.144-1.036 0.059
Serum creatinine 0.995 0.980-1.010 0.485
eGFR 0.991 0.962-1.020 0.520
NT⁃proBNP 1.000 1.000-1.000 0.522
HFpEF 1.038 0.395-2.731 0.939
Course of atrial fibrillation 0.949 0.879-1.024 0.178
Rhythm control drug 0.912 0.329-2.529 0.859
Catheter ablation 0.000 0.000-0.000 0.999
Heart rate control medication 1.656 0.267-10.259 0.588
Mild⁃to⁃moderate tricuspid regurgitation 6.571 1.362-31.705 0.019
Moderate tricuspid regurgitation 10.795 3.816-30.543 <0.001
Moderate⁃to⁃severe tricuspid regurgitation 19.525 4.593-82.999 <0.001
Severe tricuspid regurgitation 20.701 5.799-73.896 <0.001
LAD 1.067 1.002-1.137 0.044
LVEDd 1.153 1.052-1.264 0.002
LVEF 0.952 0.892-1.016 0.140
Tricuspid regurgitation was subject to no tricuspid regurgitation+mild tricuspid regurgitation as the reference.
反流、较大的左心房与左心室时应积极治疗，防止 Asian Cardiovasc Thorac Ann，2020，28（7）：421-426
AFMR进一步恶化。本研究为单中心观察性研究，研 ［5］ OKURA H，TAKADA Y，YAMABE A，et al. Prevalence
究对象为住院患者，病情较严重，可能具有选择偏倚； and correlates of physiological valvular regurgitation in
入组患者中仅4例患者无三尖瓣反流，故Logistic 回 healthy subjects［J］. Circ J，2011，75（11）：2699-2704
归分析中将三尖瓣无反流患者与三尖瓣轻度反流 ［6］ JANUARY C T，WANN L S，CALKINS H，et al. 2019
AHA/ACC/HRS focused update of the 2014 AHA/ACC/
患者合并作为参照。后期课题组将继续增加样本
HRS guideline for the management of patients with atrial
量，并追踪随访数据，以求获得更加客观、全面的研
fibrillation：a report of the American college of cardiology/
究结果。
american heart association task force on clinical practice
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