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第44卷第2期                           南京医科大学学报(自然科学版)
                  2024年2月                   Journal of Nanjing Medical University(Natural Sciences)     ·205 ·


               ·临床研究·

                急性A型主动脉夹层术后主动脉远端TEVAR的效果分析



                沈 健 ,倪布清 ,李明辉          2*
                              2
                      1
                南京医科大学第一附属医院麻醉科,心脏大血管外科,江苏                      南京   210029
                1                           2


               [摘   要] 目的:探讨 Stanford A 型主动脉夹层(type A aortic dissection,TAAD)术后主动脉远端扩张及支架所致的新发破口
               (stent induced new entry,SINE)的患者采取胸主动脉腔内血管修复术(thoracic endovascular aortic repair,TEVAR)治疗的安全性
                及有效性。方法:回顾性分析南京医科大学第一附属医院2018年1月—2023年3月连续收治的27例TAAD术后支架象鼻远端
                再次TEVAR治疗的患者,统计分析27例患者孙氏手术(主动脉全弓替换+降主动脉术中支架置入术)术中资料,孙氏手术后早

                期随访结果、TEVAR 术中资料以及术后随访结果。结果:TEVAR 术后随访率 92.3%,随访时间为(35±21)个月。远期死亡 2
                例,病死率7.4%,无主动脉相关死亡病例。TEVAR术后均未出现支架内漏、移位、下肢截瘫、新发透析(TEVAR术后新发肾功
                能不全)、肠缺血或坏死等后遗症。在随访的病例中,成功收集术前及术后复查胸腹部大血管计算机断层扫描血管造影(com⁃
                puted tomographic angiography,CTA)25例(92.3%),术后6个月复查CTA提示支架象鼻远端破口均覆盖完全,胸主动脉覆膜支
                架远端真腔打开程度均满意,内脏区及下肢血管通畅程度为100%,术后1年随访患者19例,其中胸主动脉覆膜支架周围段完
                全血栓化13例(68.4%),部分血栓化6例(31.6%),真腔有效打开,支架覆盖区域真腔明显增大,假腔缩小。结论:急性A型主
                动脉夹层术后主动脉远端TEVAR治疗效果显著,无明显不良事件发生,是值得推广的手术方案。
               [关键词] A型夹层;胸主动脉腔内血管修复术;主动脉重塑
               [中图分类号] R654.2                   [文献标志码] A                       [文章编号] 1007⁃4368(2024)02⁃205⁃05
                doi:10.7655/NYDXBNSN230779


                Effect of distal aortic TEVAR after acute type A aortic dissection surgery

                                   2
                         1
                SHEN Jian ,NI Buqing ,LI Minghui 2*
                                           2
                1 Department of Anesthesiology,Department of Cardiovascular Surgery,the First Affiliated Hospital of Nanjing
                Medical University,Nanjing 210029,China

               [Abstract] Objective:To investigate the safety and efficacy of thoracic endovascular aortic repair(TEVAR)in patients with stent
                induced new entry(SINE)in the distal aortic dilation following surgical repair of type A aortic dissection(TAAD). Methods:A
                retrospective analysis was performed on 27 consecutive patients who underwent TEVAR for stent graft⁃induced distal aortic dilation in
                Nanjing Medical University First Affiliated Hospital from January 2018 to March 2023. The intraoperative data of 27 patients with Sun’s
                surgery(total aortic arch replacement plus stented elephant trunk implantation),early postoperative follow⁃up results of Sun’s surgery,

                intraoperative data of 27 patients with TEVAR and postoperative follow⁃up results were statistically analyzed. Results:The follow⁃up
                rate after TEVAR was 92.3%,with a mean follow⁃up time of(35±21)months. There were two cases of long⁃term mortality,resulting in a
                mortality rate of 7.4%,with no deaths related to aortic complications. No stent graft leak,displacement,paraplegia,new⁃onset dialysis
               (post⁃TEVAR new⁃onset renal dysfunction),intestinal ischemia,or necrosis was observed after TEVAR. Among the follow⁃up cases,

                preoperative and postoperative computed tomographic angiography(CTA)of the thoracoabdominal vessels were successfully obtained
                in 25 cases(92.3%). At 6 months postoperatively,CTA revealed that the rupture was completely covered,the distal true cavity opening
                of the thoracic aorta was satisfactory,and the vascular patency of the internal organs and lower limbs was 100%. 19 patients were
                followed up 1 year after surgery. Among them,there were 13 cases(68.4%)of complete thrombolysis and 6 cases(31.6%)of partial
                thrombolysis,the true lumen was effectively opened,the true lumen of the stent covered area was significantly enlarged,and the false
                lumen was reduced. Conclusion:TEVAR treatment of distal aorta after acute type A aortic dissection is effective without significant

               [基金项目] 国家自然科学基金(82200340)
                ∗
                通信作者(Corresponding author),E⁃mail:lmh0221@163.com
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