Page 40 - 南京医科大学自然版
P. 40

第44卷第8期
               ·1068 ·                           南 京    医 科 大 学 学         报                        2024年8月


              动物模型验证 ME3 对 HCC 发生发展的影响及其可                            warburg effect to facilitate tumorigenesis and metastasis
              能机制。                                                   of HCC by transcriptionally activating PFKM[J]. Ther⁃
                                                                     anostics,2021,11(12):5926-5938
             [参考文献]
                                                                [11]LEE D,ZHANG M S,TSANG F H,et al. Adaptive and
             [1] QIU H B,CAO S M,XU R H. Cancer incidence,mortality,  constitutive activations of malic enzymes confer liver cancer
                   and burden in China:a time⁃trend analysis and comparison  multilayered protection against reactive oxygen species[J].
                   with the United States and United Kingdom based on the  Hepatology,2021,74(2):776-796
                   global epidemiological data released in 2020[J]. Cancer  [12]ZHANG S,CHENG Z M,YU J L,et al. Malic enzyme 2
                   Commun,2021,41(10):1037-1048                      promotes the progression of hepatocellular carcinoma via
             [2] 朱德明,孔连宝,贾文博,等. ANKRD1通过介导上皮细                        increasing triglyceride production[J]. Cancer Med,2021,
                   胞间充质转化促进肝细胞肝癌增殖与转移[J]. 南京医                        10(19):6795-6806
                   科大学学报(自然科学版),2023,43(4):484-491              [13]MIHARA Y,AKIBA J,OGASAWARA S,et al. Malic
             [3] HANAHAN D,WEINBERG R A. Hallmarks of cancer:        enzyme 1 is a potential marker of combined hepatocellular
                                                                     cholangiocarcinoma ,subtype with stem ⁃ cell features ,
                   the next generation[J]. Cell,2011,144(5):646-674
                                                                     intermediate ⁃ cell type[J]. Hepatol Res,2019,49(9):
             [4] POFF A,KOUTNIK A P,EGAN K M,et al. Targeting the
                   Warburg effect for cancer treatment:ketogenic diets for  1066-1075
                   management of glioma[J]. Semin Cancer Biol,2019,56:  [14]EDIRIWEERA M K,TENNEKOON K H,SAMARA⁃
                                                                     KOON S R. Role of the PI3K/AKT/mTOR signaling
                   135-148
                                                                     pathway in ovarian cancer:Biological and therapeutic
             [5] WANG Y P,SHARDA A,XU S N,et al. Malic enzyme 2
                   connects the Krebs cycle intermediate fumarate to mito⁃  significance[J]. Semin Cancer Biol,2019,59:147-160
                                                                [15]LIEN E C,DIBBLE C C,TOKER A. PI3K signaling in
                   chondrial biogenesis[J]. Cell Metab,2021,33(5):1027-
                                                                     cancer:beyond AKT[J]. Curr Opin Cell Biol,2017,45:
                   1041
                                                                     62-71
             [6] LEE W C,JI X,NISSIM I,et al. Malic enzyme couples
                                                                [16]ZHANG Y,LIU S,MA J L,et al. Apocynumvenetum leaf
                   mitochondria with aerobic glycolysis in osteoblasts[J].
                                                                     extract alleviated doxorubicin ⁃ induced cardiotoxicity
                   Cell Rep,2020,32(10):108108
                                                                     through the AKT/Bcl⁃2 signaling pathway[J]. Phytomedi⁃
             [7] ZHANG Q,LI J,TAN X P,et al. Effects of ME3 on the
                                                                     cine,2022,94:153815
                   proliferation,invasion and metastasis of pancreatic cancer
                                                                [17] TIAN L Y,SMIT D J,JÜCKER M. The role of PI3K/
                   cells through epithelial⁃mesenchymal transition[J]. Neo⁃
                   plasma,2019,66(6):896-907                         AKT/mTOR signaling in hepatocellular carcinoma metab⁃
             [8] 陈    曦,韩    秀,唐   宇,等. 苹果酸酶 3(ME3)对人脑               olism[J]. Int J Mol Sci,2023,24(3):2652
                   胶质瘤细胞的增殖、迁移、侵袭及间质转换的影响[J].                   [18]REN J G,SETH P,CLISH C B,et al. Knockdown of malic
                   中国细胞生物学学报,2018,40(6):867-875                      enzyme 2 suppresses lung tumor growth,induces differen⁃
             [9] SHAH M M,MEYER B I,RHEE K,et al. Conditional        tiation and impacts PI3K/AKT signaling[J]. Sci Rep,
                   survival analysis of hepatocellular carcinoma[J]. J Surg  2014,4:5414
                   Oncol,2020,122(4):684-690                                              [收稿日期] 2023-11-27
             [10] ZHOU Y M,LIN F R,WAN T,et al. ZEB1 enhances                                 (本文编辑:戴王娟)
   35   36   37   38   39   40   41   42   43   44   45