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中,远端切除范围一般不超精阜,这也是勃起神经 century[J]. Am J Clin Exp Urol,2015,3(1):36-42
集中的位置。通常,电切或汽化引起的组织损伤深 [7] LI P,WANG C,TANG M,et al. Holmium laser enucle⁃
度是有限的,如果没有发生包膜穿孔,热能对神经 ation of prostate by using en⁃bloc and bladder neck pres⁃
的影响很小,这可能是包括 TURP 和 HoLEP 等在内 ervation technique:technical consideration and influence
on functional outcomes[J]. Transl Androl Urol,2021,10
的多种手术方式对勃起功能没有造成明显损伤的
(1):134-142
原因 [22] 。在本研究中观察到术后 IIEF 和 EHGS 评
[8] MÜHLSTÄDT S,FRIEDL A,MOHAMMED N,et al. Five⁃
分与术前相比略有改善,但差异不显著。 这些数据
year experience with the adjustable transobturator male
表明,在大多数患者中,HoLEP 可以有效地保护勃
system for the treatment of male stress urinary inconti⁃
[23]
起功能,这一结论与其他的报道相吻合 。 nence:a single⁃center evaluation[J]. World J Urol,2017,
在本研究术后有正常顺行射精功能的患者中, 35(1):145-151
44.8%的 HoLEP 组患者精液量较术前减少,而在 [9] ALTINBAS N K,HAMIDI N. Penile Doppler ultrasonogra⁃
TURP 组中这一比例为22.8%。 前列腺液是精液的 phy and elastography evaluation in patients with erectile
重要成分,精液量减少与切除增生的腺体有关。 dysfunction[J]. Pol J Radiol,2018,83:e491-e499
HoLEP 是一种解剖性摘除术,其切除的组织量明显 [10] TEO J S,LEE Y M,HO H S S. An update on transurethral
surgery for benign prostatic obstruction[J]. Asian J Urol,
大于 TURP,因此精液量的减少也更加明显。另外,
2017,4(3):195-198
虽然我们试图保留完整的膀胱颈,但手术仍然会对
[11] BEARELLY P,AVELLINO G J. The role of benign pros⁃
内括约肌的结构造成一定的破坏,因此在表现为顺
tatic hyperplasia treatments in ejaculatory dysfunction
行射精的患者中仍有可能存在一定程度的精液逆
[J]. Fertil Steril,2021,116(3):611-617
行进入膀胱的情况,造成了射精量的减少。 [12] BRUNOCILLA E,SCHIAVINA R,BORGHESI M,et al.
综上所述,本研究初步证实,改良的整块法Ho⁃ Preservation of the internal vesical sphincter and proxi⁃
LEP具有创伤小、切除效率高、并发症发生率低等优 mal urethra during retropubic radical prostatectomy may
点,术中采用保留膀胱颈的技术,可有效减少逆行 improve earlier recovery of continence in selected patients
射精的发生,对于相对年轻的BPH患者是一种安全 [J]. Actas Urol Esp,2014,38(7):421-428
有效的手术方式。同时本研究也有一定局限性,包 [13] LEONG J Y,PATEL A S,RAMASAMY R. Minimizing
sexual dysfunction in BPH surgery[J]. Curr Sex Health
括其回顾性研究的属性以及采用的主观评估模式。
Rep,2019,11(3):190-200
[参考文献] [14] LIM NG K,BARBER N. Prostatic hydroablation(Aquab⁃
[1] VUICHOUD C,LOUGHLIN K R. Benign prostatic hyper⁃ lation):a new effective ultrasound guided robotic waterjet
plasia:epidemiology,economics and evaluation[J]. Can J ablative surgery for treatment of benign prostatic hyper⁃
Urol,2015,22:1-6 plasia[J]. Arch Esp Urol,2019,72(8):786-793
[2] BOUHADANA D,NGUYEN D D,ZORN K C,et al. Pa⁃ [15] HERRMANN T R W,GRAVAS S,DE LA ROSETTE J J,
tient perspectives on benign prostatic hyperplasia sur⁃ et al. Lasers in transurethral enucleation of the prostate⁃
gery:a focus on sexual health[J]. J Sex Med,2020,17 do we really need them[J]. J Clin Med,2020,9(5):1412
(10):2108-2112 [16] ZHANG J,OU Z,ZHANG X,et al. Holmium laser enucle⁃
[3] YILMAZ M,ESSER J,SUAREZ ⁃ IBARROLA R,et al. ation of the prostate versus thulium laser enucleation of
Safety and efficacy of laser enucleation of the prostate in the prostate for the treatment of large⁃volume prostates >
elderly patients⁃a narrative review[J]. Clin Interv Aging, 80 ml:18 ⁃ month follow ⁃ up results[J]. World J Urol,
2022,17(8):15-33 2020,38(6):1555-1562
[4] LEE M S,ASSMUS M,AGARWAL D,et al. Contempo⁃ [17] LARGE T,KRAMBECK A E. Evidence⁃based outcomes
rary practice patterns of transurethral therapies for benign of holmium laser enucleation of the prostate[J]. Curr
prostate hypertrophy:results of a worldwide survey[J]. Opin Urol,2018,28(3):301-308
World J Urol,2021,39(11):4207-4213 [18] KIM J K,CHO M C,SON H,et al. Patient perception of
[5] YU J,JEONG B C,JEON S S,et al. Comparison of effica⁃ ejaculatory volume reduction after holmium laser enucle⁃
cy of different surgical techniques for benign prostatic ob⁃ ation of the prostate(HoLEP)[J]. Urology,2017,99:
struction[J]. Int Neurourol J,2021,25(3):252-262 142-147
[6] MICHALAK J,TZOU D,FUNK J. HoLEP:the gold stan⁃ [19] KUEBKER J M,MILLER N L. Holmium laser enucleation
dard for the surgical management of BPH in the 21(st) of the prostate:patient selection and outcomes[J]. Curr

