Page 85 - 南京医科大学学报自然科学版

第42卷第12期 李晓慧，陈旭锋，汪 璇，等. 核心梗死体积对大血管闭塞性急性缺血性脑卒中早期临床预后的
2022年12月 预测价值［J］. 南京医科大学学报（自然科学版），2022，42（12）：1716-1721，1727 ·1721 ·

究中，将扩大样本量，寻找更多的预后不佳的危险因 farct volume post thrombectomy：characteristics，out⁃
素。本文选取的时间窗为发病4.5 h内，但在实际临 comes，and predictors［J］. World Neurosurg，2020，139：
床中，还有更多患者发病于醒后或没有十分清楚的发 e748-e753
［12］ SARRAJ A，HASSAN A E，SAVITZ S，et al. Outcomes of
病时间，希望基于CTP的核心梗死体积对预后的预测
endovascular thrombectomy vs medical management
价值能扩展应用到此类患者，从而使更多患者受益。
alone in patients with large ischemic cores：a secondary
［参考文献］ analysis of the optimizing patient's selection for endovas⁃
cular treatment in acute ischemic stroke（SELECT）study
［1］ SWEID A，HAMMOUD B，RAMESH S，et al. Acute isch⁃
［J］. JAMA Neurol，2019，76（10）：1147-1156
aemic stroke interventions：large vessel occlusion and be⁃
［13］ KIMMEL E R，AL K S，HARVEY J B，et al. Absence of
yond［J］. Stroke Vasc Neurol，2020，5（1）：80-85
［2］ 汪琛栋，贾振宇，施海彬. 急性缺血性脑卒中颅内血栓 collaterals is associated with larger infarct volume and
的研究进展［J］. 南京医科大学学报（自然科学版）， worse outcome in patients with large vessel occlusion and
mild symptoms［J］. J Stroke Cerebrovasc Dis，2019，28
2022，42（1）：137-141
（7）：1987-1992
［3］ OSPEL J M，KAPPELHOF M，KASHANI N，et al. Effect
［14］ NANNONI S，CEREDA C W，SIRIMARCO G，et al. Col⁃
of age and baseline ASPECTS on outcomes in large⁃ves⁃
laterals are a major determinant of the core but not the
sel occlusion stroke：results from the HERMES collabora⁃
penumbra volume in acute ischemic stroke［J］. Neuroradi⁃
tion［J］. J Neurointerv Surg，2021，13（9）：790-793
ology，2019，61（9）：971-978
［4］ HELDNER M R，CHALOULOS⁃IAKOVIDIS P，PANOS
［15］ VAGAL A，MENON B K，FOSTER L D，et al. Association
L，et al. Outcome of patients with large vessel occlusion in
between CT angiogram collaterals and CT perfusion in the
the anterior circulation and low NIHSS score［J］. J Neu⁃
interventional management of stroke Ⅲ trial［J］. Stroke，
rol，2020，267（6）：1651-1662
2016，47（2）：535-538
［5］ RAZA S A，BARREIRA C M，RODRIGUES G M，et al.
［16］ SONG D，YOO J，BAEK J H，et al. Infarct core expansion
Prognostic importance of CT ASPECTS and CT perfusion
on computed tomography before and after intravenous
measures of infarction in anterior emergent large vessel
thrombolysis［J］. Yonsei Med J，2018，59（2）：310-316
occlusions［J］. J Neurointerv Surg，2019，11（7）：670-674
［17］ YOSHIMOTO T，INOUE M，TANAKA K，et al. Identify⁃
［6］ LIN L，BIVARD A，KRISHNAMURTHY V，et al. Whole⁃
ing large ischemic core volume ranges in acute stroke that
brain CT perfusion to quantify acute ischemic penumbra
can benefit from mechanical thrombectomy［J］. J Neuroin⁃
and core［J］. Radiology，2016，279（3）：876-887
terv Surg，2021，13（12）：1081-1087
［7］ ZAIDI S F，AGHAEBRAHIM A，URRA X，et al. Final in⁃
［18］ GILGEN M D，KLIMEK D，LIESIROVA K T，et al. Young⁃
farct volume is a stronger predictor of outcome than recan⁃
er stroke patients with large pretreatment diffusion⁃weight⁃
alization in patients with proximal middle cerebral artery
ed imaging lesions may benefit from endovascular treat⁃
occlusion treated with endovascular therapy［J］. Stroke，
ment［J］. Stroke，2015，46（9）：2510-2516
2012，43（12）：3238-3244 ［19］ NAWABI J，FLOTTMANN F，HANNING U，et al. Futile
［8］ ALBERS G W，GOYAL M，JAHAN R，et al. Relation⁃
recanalization with poor clinical outcome is associated
ships between imaging assessments and outcomes in soli⁃
with increased edema volume after ischemic stroke［J］.
taire with the intention for thrombectomy as primary en⁃ Invest Radiol，2019，54（5）：282-287
dovascular treatment for acute ischemic stroke ［J］. ［20］ GANESH A，AL⁃AJLAN F S，SABIQ F，et al. Infarct in a
Stroke，2015，46（10）：2786-2794 new territory after treatment administration in the ES⁃
［9］ SENERS P，BEN H W，LAPERGUE B，et al. Prediction CAPE randomized controlled trial（endovascular treat⁃
of early neurological deterioration in individuals with mi⁃ ment for small core and anterior circulation proximal oc⁃
nor stroke and large vessel occlusion intended for intrave⁃ clusion with emphasis on minimizing CT to recanalization
nous thrombolysis alone［J］. JAMA Neurol，2021，78（3）： times）［J］. Stroke，2016，47（12）：2993-2998
321-328 ［21］ DHILLON P S，BUTT W，PODLASEK A，et al. Perfusion
［10］ ZI W，WANG H，YANG D，et al. Clinical effectiveness imaging for endovascular thrombectomy in acute ischemic
and safety outcomes of endovascular treatment for acute stroke is associated with improved functional outcomes in
anterior circulation ischemic stroke in China［J］. Cerebro⁃ the early and late time windows［J］. Stroke，2022，53（1）：
vasc Dis，2017，44（5⁃6）：248-258 1-9
［11］ TONETTI D A，DESAI S M，HUDSON J，et al. Large in⁃ （下转第1727页）